Deuterated Compounds

Applications 5-Bromo-2,4-pyrimidinedione-13C,15N2 is the isotope labelled analogue of Bromouracil, a halogenated nitrogenous base on RNA nucleosides.
References Morinaga, H., et al.: Bioorg. Med. Chem., 21, 466 (2013);

Applications Carcinogenic compound commonly found in hair dyes and henna ink, also a commonly used synthetic intermediate
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mulyono; T., et al.: J. Biosci. Bioeng., 103, 147 (2007), Mosley-Foreman, C., et al.: Food Chem. Toxicol., 46, 3780 (2008), Patel, A.K., et al.: J. Agric. Food Chem., 56, 9236 (2008), Akyuz, M., et al.: J. Pharm. Biomed. Anal., 47, 68 (2008),

Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).
References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),

Applications (±)-1-Amino-2-propanol-1,1,2,3,3,3-d6 (CAS# 1219795-13-7) is a useful isotopically labeled research compound.

Applications 2-(4-Nitrophenyl-d4)propane (CAS# 1219803-36-7) is a useful isotopically labeled research compound.

Applications Choline-d9 Bromide (N,N,N-trimethyl-d9) (CAS# 285979-71-7) is a useful isotopically labeled research compound.

Applications Labelled analogue of Potassium Cyanide, a reagent widely used in organic synthesis for the preparation of nitriles and carboxylic acids, particularly in the von Richter reaction.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kollenz, G. et al.: Org. Prep. Proc. Int., 12, 244 (1980); Subramanian, L. R.: Sci. Synth., 19, 173 (2004);

Applications n-Tetracontane-d82 (CAS# 1219802-99-9) is a useful isotopically labeled research compound.

Applications Ethylene Glycol Monostearate-d4 is a deuterated version of Ethylene Glycol Monostearate (E917480), a polymer chain used in the synthesis of PEG chains which may act as vesicles in the transport of drugs.
References Takeoka, S. et al.: J. Am. Chem. SOc., 122, 7927 (2000)

Applications Undecanoic-11,11,11-d3 Acid (CAS# 1219802-11-5) is a useful isotopically labeled research compound.

Applications 4-Hydroxypiperidine-D4 is an isotope labelled form of 4-Hydroxypiperidine (H950845), a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.
References Yang, D. et al.: Macromol., 35, 5304 (2002); Harrison, R.J. et al.: Bioorg. Med. Chem. Lett., 9, 2463 (1999);

Applications Isobutylsuccinic Acid-d9 is labelled Isobutylsuccinic Acid (I780660) which was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.
References Groutas, W., et al.: Bioorg. Med. Chem., 3, 375 (1995);

Applications (±)-2-Ethylhexyl-d17 Acetate (CAS# 1219802-70-6) is a useful isotopically labeled research compound.

Stability Volatile
Applications Isotope labelled Acetonitrile is used as a polar aprotic solvent in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hu, H.H., et al.: Phy. Chem. Phys., 15, 7666 (2013); Kim, J.Y., et al.: J. Mater. Chem. A., et al.: 1, 5982 (2013);

Applications Phenyl-d5-acetylene (CAS# 25837-46-1) is a useful isotopically labeled research compound.

Applications n-Butylamine-ND2 DCl (CAS# 156235-87-9) is a useful isotopically labeled research compound.
Chemical Name: n-Butylamine-ND2 DCl (CAS# 156235-87-9) is a useful isotopically labeled research compound.

Applications A labelled metabolite of Pantoprazole, an antiulcerative, gastric pump inhibitor.

Applications Cyclopropane-d5-carboxylic Acid (CAS# 1219804-09-7) is a useful isotopically labeled research compound.

Applications Benzyl-2,3,4,5,6-d5 Acetate (CAS# 1398065-57-0) is a useful isotopically labeled research compound.

Applications 1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium-d5 Chloride is an intermediate used in the synthesis of Girard’s Reagent P-d5 (G388502), which is a labeled girard’s reagent used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents.
References Mirzaei, H. et al.: J. Chrom. A, 1134, 122 (2007); Kanofsky, J.R. et al.: Photochem. Photobiol., 73, 349 (2001);

Applications 3-Ethyl-d5-toluene is labelled 3-Ethyltoluene which is a useful synthetic intermediate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Acetamide-d5 (CAS# 33675-83-1) is a useful isotopically labeled research compound.

Applications 3-(Cyclohexylamino)-1-propanesulfonic-d17 Acid (CAS# 1219804-15-5) is a useful isotopically labeled research compound.

Applications 2-Tetradecylcyclobutanone-D29 is a labelled analogue of 2-Tetradecylcyclobutanone (T291540).

Applications 1-Bromotetradecane-d29 is the isotope labelled analog of 1-Bromotetradecane (B688015); a compound that is part of a group of bromoalkanes that have high potential to cause allergic contact dermatitis (ACD) in humans. 1-Bromotetradecane is also a useful synthetic intermediate.
References Basketter, D., et al.: Contact Dermatitis, 27, 137 (1992); Fedorowicz, A., et al.: Chem. Res. Toxicol., 18, 954 (2005); Siegel, P., et al.: Toxicol. Sci., 107, 78 (2009)

Applications 1-Bromooctane-3,3,4,4-d4 (CAS# 1219803-37-8) is a useful isotopically labeled research compound.

Applications N-Methyl Lacosamide-d3 is the labeled analogue of N-Methyl Lacosamide (M315210), a methly analogue of Lacosamide (L098500), a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997); Barton, M., et al.: Epilepsy Res., 47, 217 (2001); Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006); Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007)

Applications 1-[5-Chloro-2-(2,4-dichlorophenoxy)phenylethanone]-d2 Major (cas# 1189477-14-2) is a compound useful in organic synthesis.

Applications 1-Chlorohexane-d13 (CAS# 1219798-45-4) is a useful isotopically labeled research compound.

Applications 4-Chlorobenzonitrile-d4 (CAS# 1219794-82-7) is a useful isotopically labeled research compound.

Applications Styrene-alpha,beta,beta-d3 (CAS# 3814-93-5) is a useful isotopically labeled research compound.

Applications 4-Aminobenzoic-​2,​3,​5,​6-​d4 Acid Methyl Ester is an intermediate in the synthesis of DMABA-d4 NHS Ester (D678402), which is a labelled DMABA NHS ester (D678400). DMABA NHS ester is a reagent that reacts with the primary amine group of PE lipids. DMABA NHS ester has been used in combination with DMABA NHS ester-d4, -d6, and -d10 to study relative changes in PE lipid abundance before and after radical oxidation.
References Wester, H., et al.: Nucl. Med. Bio., 23, 365 (1996), Frees, D., et al.: Mol. Microbiol., 48, 1565 (2003), Michel, A., et al.: J. Bacteriol., 188, 5783 (2006), Voelker, T., et al.: Bioorg. Med. Chem., 17, 2047 (2009),

Applications 2-Phenylpropane-1,1,1,3,3,3-d6 (CAS# 20201-29-0) is a useful isotopically labeled research compound.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Labeled 1,4-cyclohexanedione with high isotopic purity.
References Stibbe, W.; et al.: J. Labelled Compounds Radiopharmaceuticals, 16, 567 (1979),