Deuterated Compounds

Applications Labelled Ibuprofen alcohol (I140045). Ibuprofen alcohol is an impurity of Ibuprofen (I140000). Ibuprofen impurity P as per EP.
References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),

Applications 3-Nitro-1-pyrenol is an nitroarene which may contribute to genotoxicity associated with air pollution. This is the labeled analog.
References Kameda, T., et al.: J. Health. Sci., 57, 372 (2011); Van, B., et al.: Chem. Biol. interact., 117, 15 (1999);

Applications 2-Bromoaniline-d4 is the labeled analogue of 2-Bromoaniline (B679950), a reagent used in the synthesis of substituted 2-carboxanilides as herbicides and antibacterials. Also used in the synthesis of benzisothiazol-3-one derivatives as caspase-3 inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kos, J. et al.: Molecules, 18, 7977 (2013); Liu, D. et al.: Bioorg. Med. Chem., 21, 2960 (2013)

Applications N-Descarbo(1,4-benzodioxine), N-Acetyl Doxazosin-d8 Hydrochloride is the isotope analog of N-Descarbo(1,4-benzodioxine), N-Acetyl Doxazosin Hydrochloride. N-Descarbo(1,4-benzodioxine), N-Acetyl Doxazosin Hydrochloride is an impurity of doxazosin, which is used in biological studies to evaluate the structure activity or prazosin pharmacophore for Transport-P inhibition.
References Zunszain, P.A., et al.: Bioorg. Med. Chem., 13, 3681 (2005); Al-Damluji, S., et al.: J. Pharmacol., 124, 693 (1998)

Applications Ethyl 2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate is an intermediate in the synthesis of Bezafibrate-d4 (B341002), a labeled antilipemic agent.
References Zimmerman, R., et al.: Atherosclerosis 29, 477 (1978); Monk, J.P., et al.: Drugs, 33, 539 (1987)

Applications 1-(2,6-Dichlorophenyl)piperazine-d8 Hydrochloride is the isotope analog of 1-(2,6-Dichlorophenyl)piperazine Hydrochloride. 1-(2,6-Dichlorophenyl)piperazine Hydrochloride is used in the preparation of pyrazolopyrimidones and pyrazolopyridones as tankyrase inhibitors which are useful in the treatment of cancer.
References Feng, J., et al.: PCT Int. Appl., 2013:1906020 (2013)

Applications n-Octylbenzene-2,3,4,5,6-d5 (CAS# 1219799-23-1) is a useful isotopically labeled research compound.

Applications 21-(3-Carboxy-1-oxopropoxy)-17-hydroxy-pregn-4-ene-3,20-dione-d4 Monosodium Salt is deuterium labelled 21-(3-Carboxy-1-oxopropoxy)-17-hydroxy-pregn-4-ene-3,20-dione Monosodium Salt (a derivative of Cortisol) and exhibits multi-site antiglucocorticoid activity in vivo.
References Duncan, M. R. and Duncan, G. R. J. Steroid Biochem. 10, 245 (1979)

Applications 4-Cyano-4'-n-pentyl-d11-biphenyl (CAS# 57078-20-3) is a useful isotopically labeled research compound.

Applications Hexachloroethane-13C1 (CAS# 93952-15-9) is a useful isotopically labeled research compound.

Applications Methyl 5-Hydroxy-2-benzimidazolecarbamate-d3, is a labeled analogue of Methyl 5-Hydroxy-2-benzimidazolecarbamate (M312585), which is a derivative of Carbendazim (C175900).
References Zeng, Z., et al.: J. Agric. Food Chem., 44, 3374 (1996), Lewis, D., et al.: Xenobiotica, 28, 235 (1998), Hodgson, E., et al.: J. Biochem. Mol. Toxicol., 21, 182 (2007),

Applications Bromoethane-1,1,2,2-d4 (CAS# 25854-32-4) is a useful isotopically labeled research compound.

Applications o-Tolunitrile-d7 (CAS# 1138681-69-2) is a useful isotopically labeled research compound.

Applications (1E)-1-(4-Chlorophenyl)-4,4-dimethyl-1-penten-3-one-D9 is an intermediate in the synthesis of Isotope labelled Tebuconazole (T013002), which is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.

Applications (4-Fluorophenyl)acetic-alpha,alpha-d2 Acid (CAS# 113715-48-3) is a useful isotopically labeled research compound.