Deuterated Compounds

<p>Applications 2-Ethyl-3,4,5,6-tetrahydropyridine Hydrochloride-d3 is the isotope labelled analog of 2-Ethyl-3,4,5,6-tetrahydropyridine Hydrochloride (E926330); a compound that is produced by lactic acid bacteria (LAB) and can cause mousy off-flavor in wines.<br>References Snowdon, E.M., et al.: J. Agr. Food Chem., 54, 6465 (2006); Costello, P.J., et al.: J. Agr. Food Chem., 50, 7079 (2002); Craig, J.T., et al.: Am. J. Enol. Viticult., 35, 46 (1984)<br></p>

<p>Applications (+)-cis-Vincaminic Acid Ethyl-d5 Ester is labelled (+)-cis-Vincaminic Acid Ethyl Ester (V314210) which is a derivative of Vinpocetine (D448350). It has been shown that under stressed conditions, vinpocetine equilibrates with Vincaminic Acid Ethyl Ester and hydrolyzes to Apovincaminic Acid (A729250).<br>References Muhammad, N., et al.: J. Pharmaceu. Sci., 77, 126 (1988); Han, et al.: J. Biol. Chem., 274, 22337 (1999), O’Donnell, et al.: Pharmacol. Biochem. Behav., 63, 185 (1999);<br></p>

<p>Applications Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide. Used in Pesticide detection.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dorough, W.H., et al.: J. Agric. Food Chem., 16, 319 (1968),<br></p>

<p>Applications Chlorobenzene-3,4,5-d3 (CAS# 59164-11-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Methyl(4-methylnaphthalen-1-ylmethyl)amine-d3 is the isotope analog of Methyl(4-methylnaphthalen-1-ylmethyl)amine. Methyl(4-methylnaphthalen-1-ylmethyl)amine is a reagent in the preparation of heterocyclic compounds as enoyl-acyl carrier protein reductase FabI inhibitors and antibacterial agents.<br>References Stuetz, A., et al.: J. Med. Chem., 29, 112 (1986); Berman, J., et al.: PCT Int. Appl., 2004:515512 (2004)<br></p>

<p>Applications 2-Chloropropane-2-d1 (CAS# 53778-42-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-1-Butyl-d9-1-demethylethyl Torsemide is labelled N-1-Butyl-1-demethylethyl Torsemide (B692375) which is an impurity of Torsemide (T548750), diuretic.<br>References Lesne, M., et al.: In. J. Clin. Pharmacol. Ther. Toxicol., 20, 382 (1982), Brater, D.C., et al.: Clin. Pharmacol. Ther., 42, 187 (1987),<br></p>

<p>Applications 1,5-Dibromopentane-d10 (CAS# 1219802-90-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Eicosanoic-20,20,20-d3 Acid (CAS# 202480-70-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications N,N-Dimethyl-d3-glycine HCl (N-methyl-d3) (CAS# 1219795-14-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methyl-d3-epsilon-caprolactam (CAS# 203645-60-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Fmoc-(13C9,15N)-L-Tyrosine O-Tertbutyl Ether is the isotope labelled protected form of L-Tyrosine (T899975), an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.<br>References Gülçin, ?.: Amino Acids, 32, 431 (2007); Langen, K., et al.: Nuc. Med. Biol., 29, 625 (2002); Schallreuter, K., et al.: J. Invest. Derm., 104, 953 (1995); Zhang, W., et al.: Neuropharmacology, 47, 438 (2004)<br></p>

<p>Applications Methyl trans-Cinnamate-d5 (phenyl-d5) (CAS# 61764-82-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications p-Xylene-alpha,alpha,alpha-d3 (CAS# 26204-18-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Dichlorobenzene (D4, 98%) (cas# 2199-70-4) is a useful research chemical.<br></p>

<p>Applications Benzyl Octyl Adipate-d17, is the labeled analogue of Benzyl Octyl Adipate (B285580), which is used as plasticizer. It can also be used for the synthesis of orally effective acid prodrugs of the β-Lactamase inhibitor Sulbactam (S699185).<br>References Sorokin, G. A., Plasticheskie Massy, 25 (1976); Kraus, A., Farbe + Lack,60, 185 (1954); English, A. R., et al.: J. Med. Chem., 33, 344 (1990);<br></p>