Organic Halides

<p>4,5-Dichloro-1-(4-nitrophenyl)imidazole is a unsymmetrical aryl halide that has been used for the synthesis of various ligands. This compound can be synthesized by reacting an imidazole with an aryl chloride in the presence of copper as catalyst. 4,5-Dichloro-1-(4-nitrophenyl)imidazole yields are low and it is soluble in organic solvents. It has been shown to have luminescence properties. The compound has been used for research purposes.</p>

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<p>2-(2,4-Dichlorophenoxy)acetohydrazide (2,4-DAH) is a phenacyl analogue that has been shown to have anti-cancer and anti-inflammatory activities. It inhibits the cyclooxygenase enzyme, which is involved in the synthesis of prostaglandins. This inhibition leads to a decrease in production of inflammatory mediators such as prostaglandin E2 and leukotriene B4. 2,4-DAH also potently inhibits human fibroblast cells and cancer cells with IC50 values of 3.7 μM and 10 μM respectively. The most common side effects are nausea, vomiting, headache, dizziness, lightheadedness, and diarrhea.</p>

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4-Iodobenzaldoxime is an isoxazoline, phenyl derivative that forms a 4-iodobenzaldehyde oxime from a 4-bromobenzaldehyde or 4-chlorobenzaldehyde. This compound has been used for the synthesis of organic compounds and pharmaceuticals. The reaction is catalyzed by acid or base in water or alcohol.

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Flunarizine is a drug that blocks voltage-gated calcium channels. It is used as an anticonvulsant, antiemetic, and to treat migraine headaches. Flunarizine is often called the prototypical l-type calcium channel blocker. It was discovered in 1957 by scientists at the Bristol-Myers Company and has been marketed since 1961 under the trade name of "Akineton". Flunarizine binds to voltage-gated calcium channels in nerve cells and prevents the entry of calcium ions into these cells. This inhibits neurotransmitter release from neurons, which prevents pain signals from being sent to the brain. Flunarizine has been shown to be active against inflammatory pain, but not mechanical pain or neuropathic pain. Flunarizine has also been shown to be an inhibitor of ruthenium complexes with phenyl groups.

Please enquire for more information about 4-(4-Bromophenyl)-2-(3-methyl-5-oxo-1-phenyl(2-pyrazolin-4-yl))-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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