Organic Halides

<p>Applications 4-Amino-2-fluorophenol is an reagent used in various synthetic preparations such as the synthesis of Amodiaquine (A634200), an antimalarial agent.<br>References O’Neill, P.M., et al.: J. Med. Chem., 37, 1362 (1994); Berg, S.S., et al.: J. Chem. Soc., 642 (1949);<br></p>

<p>Applications 4-(Bromomethyl)-2-fluorobenzonitrile is a useful building block for the preparation and optimization of the highly selective GLUT1 inhibitor, BAY-876.<br>References Siebeneicher, H., et al.: ChemMedChem, 11, 2261-2271 (2016);<br></p>

<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Chlorobutanal Dimethyl Acetal 90% is a compound useful in organic synthesis and other chemical processes. It is used as an intermediate in the synthesis of aripiprazole, buspirone, and NAN-190 via reductive alkylation of piperazine derivatives with aldehydes<br>References Kowalski, P., et al.: Archiv der Pharmazie, 345, 81 (2012)<br></p>

<p>Applications 4-Bromo-2-nitroaniline is used for the synthesis of reagents such as ethyltriphenylphosphonium tribromide;<br>References Jamir, L., et al.: Synthetic. Comm., 41, 147 (2011); Reuter, R., et al.: Euro. J. Org. Chem., 32, 5647 (2009);<br></p>

<p>Applications Phosphorodichloridic Acid is an intermediate used in the synthesis of Cefotiam Dihydrochloride-13C, 15N2 (C243007), which is labelled Cefotiam Dihydrochloride (C243005), which is an antibiotic product used in injections to treat bacterial infections. Cefotiam Dihydrochloride can also reduce allergic reactions and mixed with pharmaceutical carriers for medical formulations.<br>References Jiang, C., et al.: Faming Zhuanli Shenqing, CN 105646539 A, 20160608 (2016); Liu, X.: Faming Zhuanli Shenqing, CN 105193819 A, 20151230, (2015); Weng, Y., et al.: Faming Zhuanli Shenqing, CN 103601737 A. 20140226 (2014)<br></p>

<p>Applications 4-Morpholin-4-yl-but-2-enoic acid hydrochloride (cas# 1807940-64-2) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 2,4,6-Trifluorobenzene-1,3,5-tricarbonitrile (cas# 3638-97-9) is a useful research chemical.<br></p>

<p>Applications Ethyl 3,5-dichloro-4-hydroxybenzoate (cas# 17302-82-8) is a useful research chemical.<br></p>

<p>Applications O-(2-Bromo-6-chlorophenyl) O-Ethyl S-Propyl Phosphorothioate is a useful intermediate.<br></p>

<p>Applications 4-Pentylbromobenzene is a derivative of Valerophenone (V091450), which is an aromatic ketone that is often used as a tool in the study of various photochemical processes. Valerophenone is also an inhibitor of the enzyme carbonyl reductase.<br>References Lewis, F.D.: Mol. Photochem., 4, 49 (1972); Turro, N.J. et al.: Photochem. Photobiol., 26, 413 (1977); Imamura,Y. et al.: J. Enzyme Inhib. Med. Chem., 22, 105 (2007);<br></p>

<p>Applications SIB 1553A hyrdrochloride is a novel cognitive enhancer with selectivity for neuronal nicotinic acetylcholine receptors (nAChR).<br>References Vernier, J.M., et al.: J. Med. Chem., 42, 1684 (1999)<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Fluorobenzoyl Chloride is used in the synthesis of tryphostins which act as inhibitors of EGF receptor and Erb82/neu tyrosine kinases. Also used in the synthesis of 1,2,4-triazole-3-thiones as antidepressant agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gazit, A. et al.: J. Med. Chem., 34, 1896 (1991); Kane, J. et al.: J. Med. Chem.,<br></p>