Organic Halides

<p>Applications 4-Chlorobenzenesulfonic acid is an aromatic compound that is used to synthesize a variety of sulfonyl azides. 4-Chlorobenzenesulfonic acid is also used for its effectivenes in promoting para-selective reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bovonsombat, P., et al.: Tetrahedron, 66, 6928 (2010); Kiani, A., et al.: J. Sulf. Chem., 35, 119 (2014)<br></p>

<p>Applications 3-bromo-N1,N1-dimethylbenzene-1,4-diamine (cas# 107100-00-5) is a useful research chemical.<br></p>

<p>Applications tert-Butylhydrazine Hydrochloride is a a hydrazine compound used in organic synthesis for aromatic nucleophilic N-N exchange reaction. tert-Butylhydrazine Hydrochloride is also used in the preparation of insect growth regulator.<br>References Hojo, M. et al.: Synthesis, 6, 481 (1990); Zhang, J. et al.: Huax. Shijie, 36, 576 (1995);<br></p>

<p>Stability Very Moisture Sensitive<br>Applications Chlorotriphenylstannane is used in the synthesis of nanoparticles which bear triamide ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shariatinia, Z. et al.: Beil. J. Nanotech., 4, 94 (2013);<br></p>

<p>Applications 2,3,4-Trichlorophenylboronic acid (cas# 352530-21-3) is a useful research chemical.<br></p>

<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>

<p>Applications METHYL PERFLUOROHEXANOATE (cas# 424-18-0) is a useful research chemical.<br></p>

<p>Applications Fluorinert FC 40 is a colorless, thermally stable, fully- fluorinated liquid. A useful modifier for the design of soft porous polymers.<br>References Turani-i-Belloto, A., et al.: Polymers (Basel, Switzerland), 12, 1008 (2020)<br></p>

<p>Applications 2-Amino-N-(2-aminoethyl)benzamide hydrochloride is used in biological studies for immunization with recombinantly expressed glycan antigens from Schistosoma mansoni which induces glycan-specific antibodies against parasite.<br>References Prasanphanich, N. S., et al.: Glycobiology, 24, 619 (2014);<br></p>

<p>Applications Bromonitromethane is used in the preparaton of [2,3-d]pyrimidines as inhibitors of Lck which can be used in the treatment of diseases where T-cell proliferation is unwanted. It is also used in the synthesis of isoxazoline N-oxides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References DiMauro, E. et al.: Bioorg. Med. Chem. 17, 2305 (2007); Kunetsky, R. et al.: Org. Lett., 5, 4907 (2003);<br></p>

<p>Applications 2,4-Dichloro-3,5-dinitrobenzotrifluoride is a reagent used in the synthesis of kinesin spindle protein inhibitors. Potential use as an alternative to neurotoxic MT inhibitors.<br>References Dong, J. et al.: Eur. J. Med. Chem., 70, 427 (2013);<br></p>

<p>Applications Trimethyl-tetradecylammonium chloride,99% (cas# 4574-04-3) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Pentachloroacetone is a disinfection byproduct.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jeong, C., et al.: Environ. Sci. Technol., 46, 12120 (2012); Colman, J., et al.: Toxicol. Appl. Pharm., 254, 100 (2011)<br></p>

<p>Applications 3-Iodobenzoic Acid (cas# 618-51-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Methoxyacetyl chloride<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Allyl Bromide is used as a reagent in the synthesis of Resveratrol derivatives. Resveratrol (R150000) is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression.<br> E0<br>References Powell, R.G., et al.: Phytochemistry, 35, 335 (1994), Jeandet, P., et al.: J. Phytopathol., 143, 135 (1995), Mattivi, F., et al.: J. Agric. Food Chem., 43, 1820 (1995); Mulakayala, C. et al.: J. Mol. Graph. Model., 41, 43 (2013);<br></p>

<p>Applications 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.<br>References Deng, J. et alJ. App. Polym., 108, 2023 (2008); Zhu, Y. et al.: New. J. Chem., 37, 890 (2013);<br></p>

<p>Applications 3-Chlorophenol is a halophenol with antifungal activity. 3-Chlorophenol is commonly used as a building block in the preparation of variety of biologically active compounds. Studies suggest that 3-Chlorophenol can be used in the regeneration of vegetal activated carbons.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gershon, H. et al.: Monatsh. Chem., 126, 1161 (1995); Dranca, I.: Environ. Eng. Man. J., 5, 203 (2006);<br></p>

<p>Applications An oxidizing agent, especially in steroid synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications CHLOROFLUOROACETAMIDE (cas# 431-09-4) is a useful research chemical.<br></p>

<p>Applications 2-Amino-4-chlorobenzoic Acid is used in the preparation of quinazolinone derivatives observed to be useful in the treatment of Alzheimer’s disease. Also it aids in the synthesis of non-nucleoside, thumb pocket 2 HCV NS5B polymerase inhibitors used in Hepatitis C therapy.<br>References Stammers, T. et al.: Bioorg, Med, Chem. Lett., 23, 2585 (2013);<br></p>

<p>Applications Methyl 6-aminohexanoate is used as a reagent to synthesize straight chain hydroxamates, compounds that act as inhibitors of Human Histone Deacetylase (HDAC) that have the potential to treat cancer. Methyl 6-aminohexanoate is also sometimes used as a spacer unit for peptide synthesis.<br>References Matthews, S., et al.: J. Chem. Soc. Chem. Commun., 17, 1809 (1995); Remiszewski, S., et al.: J. Med. Chem., 45, 753 (2002)<br></p>

<p>Applications 4-Chloro-1,1’-biphenyl (cas# 2051-62-9) is a compound useful in organic synthesis.<br></p>

<p>Applications (3-Azidopropyl)triphenylphosphonium Bromide (cas# 127611-39-6) is a compound useful in organic synthesis.<br></p>

<p>Applications An intermediate for the preparation of Brimonidine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Benzyl 2-Chloroethyl Ether is used in the synthesis of phosphane ligands with novel linker units that are complexed with rhodium to be used as building blocks for dendrimer catalysts. Also used in the formation of 2,6-diphenylpyrazine molecule derivatives which display cytotoxic properties.<br>References Findeis, R. et al.: Eur. J. Inorg. Chem., 1, 99 (2003); Dias, N. et al.: Eur. J, Med. Chem., 40, 1206 (2005);<br></p>

<p>Applications 2-(2-bromo-4,5-dimethoxyphenyl)ethan-1-amine hydrochloride (cas# 103275-23-6) is a useful research chemical.<br></p>

<p>Applications 2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. 2-(2-Chloroethoxy)ethanol is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).<br>References McClay, K. et al.: Appl. Environ. Microbiol., 73, 6870 (2007); David, F<br></p>

<p>Applications 9-(2-Chloro-ethyl)-9H-purin-6-ylamine (cas# 19255-48-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,1-Dichloro-2-propanone is a disinfection byproduct in drinking water. It may cause bladder cancer and other adverse health effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Farre, M., et al.: Water Sci. Tehnol., 12, 573 (2012); Catherine, M., et al.: Water Res., 47, 3231 (2013); Neale, P., et al.: Environ. Sci. Technol., 46, 10317 (2012)<br></p>

<p>Applications 2-Fluorobenzamide (cas# 445-28-3) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Trichloromethyl chloroformate is used as a reagent to prepare diisocyanates (e.g. Tolylene 2,4-Diisocyanate [T536710]) with benzene or Furan (F863650) rings. Trichloromethyl chloroformate is also used as a dehydrating agent in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mai, K. &amp; Patil, G.: Tetrahedron Lett., 27, 2203 (1986); Nowakowski, J.: Prak. Chem.-Chem. Ztg., 334, 187 (1992)<br></p>

<p>Stability Volatile<br>Applications 1,2-Dichlorotrifluoroethyl trifluoromethyl ether (cas# 2356-53-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light and Moisture Sensitive<br>Applications A photoaffinity reagent.<br>References Hatanaka, Y. et al: Bioorg. Med. Chem., 2, 1367 (1994); Hatanaka, Y. et al: J. Org. Chem., 59, 383 (1994); Hatanaka, Y. et al: Bioorg. Med. Chem. 2, 1367 (1994)<br></p>

<p>Applications 2-Amino-3,5-dibromobenzoic acid (cas# 609-85-8) is a useful research chemical.<br></p>

<p>Applications 4-(2-Chlorophenyl)-cyclohexanone is used in the synthetic preparation of cyclohexyl pyridylpiperazines as Δ8-Δ7 sterol isomerase ligands with antiproliferative activity.<br>References Berardi, F., et al.: J. Med. Chem., 51, 7523 (2008)<br></p>

<p>Applications Bromocyclobutane<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-[(2-Chlorophenyl)(methylimino)methyl]cyclopentanol has potential use as a component of household cleaning solution products. IT is also an intermediate in the production of the cyclohexanone analogue.Ketamine (K165300) related compound.<br></p>

<p>Applications Ethylenebis(tetrabromophthalimide) is an additive fire retardant that is added to a polymer mixture to produce a blend. Ethylenebis(tetrabromophthalimide) is used in high impact polystyrene (HIPS), polyethylene, polypropylene, thermoplastic polyesters, polyamide, ethylene propylene-diene terpolymers (EPDM rubbers) and other synthetic rubbers, polycarbonate, ethylene copolymers, ionomer resins, epoxies, and textile treatments.<br>References Clausen, E., et al.: Anal. Chem., 327, 297 (1987);<br></p>

<p>Applications 2-Amino-6-fluorobenzothiazole is a useful research chemical. An intermediate for the synthesis of benzothiazoles and aminobenzothiazoles with antimicrobial activity.<br>References Defrenza, I., et al.: J. Heterocycl. Chem., 52, 1705 (2015); Catalano, A., et al.: Eur. J. Med. Chem., 64, 357 (2013)<br></p>

<p>Applications 2,2,2-Trifluoroethyl Tosylate is a trifluoroethylation agent used in the preparation of 2,2,2-trifluoroethyl phenyl sulfone, a potential 2,2,2-trifluoroethyl pronucleophile.<br>References Zhang, W., et. al.: Tetrahedron Lett., 53, 6565 (2012)<br></p>

<p>Applications An intermediate in the manufacturing of Nylon.<br></p>

<p>Stability Moisture Sensitive<br>Applications Tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate (cas# 19186-97-1) is a useful research chemical.<br></p>

<p>Applications 5-Bromo-2-thiophenecarboxaldehyde is used in biological studies as anti-inflammatory and anti-tumor activity of the marine mangrove Rhizophora apiculata.<br>References Prabhu, V.V., et al.: J. Immunotoxicol., 9, 341 (2012);<br></p>

<p>Applications 2-Bromoethanol is an widely used intermediate in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tian, Z., et al.: Int. J. Quant. Chem., 111, 631 (2011); Thayer, F.K., et al.: Org. Syntheses., 6, (1926);<br></p>

<p>Applications 1H,1H,2H,2H-Perfluorodecyltriethoxysilane is used in making thin film transistors, polyethersulfone membranes, and a superwettable Janus membrane.<br>References Zhu, Zhigao, et al.: J. of Membrane Sci., 563, 602-609 (2018); Khan, Aftab A., et al.: Separation and Purification Tech., 210, 20-28 (2019); Shih, Andy, et al.: MRS Adv., 3(33), 1877-1882 (2018)<br></p>

<p>Applications 9,​9-​Bis(methoxymethyl)​-​9H-​fluorene is a compound involved in the preparation of polypropylene by heterogeneous Ziegler-Natta catalyst.<br>References Luo, Z., et al.: Ind. Eng. Chem. Res., 54, 11247-11250 (2015)<br></p>