Organic Halides

Applications 7-bromohept-1-yne (cas# 81216-14-0) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1,2,4,5-Tetrafluorobenzene (cas# 327-54-8) is a useful research chemical.

Applications 2,6-Dichloro-1,4-phenylenediamine is an aromatic amine that can be found in azo dyes. It was studied for potential mutagenic and toxic properties.
References Crettaz, S., et al.: J. Verbrauch. Lebensm., 15, 49 (2020)

Applications N-Fluorobenzenesulfonimide is a mild electrophilic fluorinating reagent

Applications 2-(2,2,2-Trifluoroethoxy)phenol is a reactant used for the preparation of phenyl acetate compounds with short sedative and hypnotic effect.

Applications Phenylsulfenyl Chloride is an intermediate used in the synthesis of Tabanone (T003450), which is found in oils of Trifolium pratense L. and is a potential natural anti-oxidant.
References Vlaisavljevic, S., et. al.: Molecules, 19, 713 (2014)

Applications 1-(4-Bromophenyl)ethane-1,2-diol is used as a reactant in the regioselective palladium-catalyzed O,S rearrangement of cyclic thiocarbonates.
References Mahy, William, et al.: Euro. J. of Org. Chem., 2017(43), 6441-6444 (2017)

Stability Air Sensitive
Applications 4-IODO-2-NITROANILINE (cas# 20691-72-9) is a useful research chemical.

Applications 4-Bromo-2-(trifluoromethyl)benzoic acid

Impurity Budesonide EP Impurity J
Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.
References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)

Stability Unstable in Solution
Applications 4-Chloro-3,5-dinitrobenzonitrile is a reagent used in the synthesis of lodoxamide (L469365). Lodoxamide is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.
References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)

Applications 1,2-Dichloro-4-nitrobenzene is an intermediate in the synthesis of agrochemicals. Studies have been conducted to use 1,2-Dichloro-4-nitrobenzene as an organic intermediate for the synthetic preparation of ciprofloxacin (C482500).
References Lu, C.S., et al.: Adv. Mater. Res., 396, 2379 (2012); Suzuki, H., et al.: Synthesis., 841 (1994); Wang, P.C., et al.: Cataly. Commun., 14, 42 (2011);

Applications 4-Aminocatechol Hydrochloride is an acidic salt form of 4-Aminocatechol (A603280). 4-Aminocatechol is a phenol derivative with inhibitory activity against matrix metalloproteinase (MMP).
References Rubino, M.T. et al.: Arch. Pharm., 344, 557 (2011);

Applications Difluoro Atorvastatin Acetonide tert-Butyl Ester is a useful synthetic intermediate in the synthesis of Difluoro Atorvastatin (D445660); an Atorvastatin impurity.
References Dart, A., et al.: Am. J. Cardiol., 80, 39 (1997)

Applications 6-Fluoronicotinic acid

Applications 2-Bromo-6-morpholinobenzonitrile (cas# 1129540-65-3) is a useful research chemical.

Applications 2-(2-(4-Chlorophenoxy)phenyl)acetic acid is used in the preparation of tri-substituted thiazoles as RAGE antagonists in Alzheimer treatments.
References Lee, Y. et al.: Bioorg. Med. Chem. Lett., 22, 7555 (2012);

Applications 5-(Aminomethyl)-2,3-dihydro-1H-inden-1-one Hydrochloride is a useful research chemical for organic synthesis.

Applications Methyl 3-chloro-3-oxopropionate is a reagent that is used in the synthesis of pyrrolopiperidinone acetic acids as CRTh2 antagonists/
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Andres, M., et al.: Bioorg. Med. Chem. Lett., 24, 5111 (2014);

Applications Bromochlorophen (cas# 15435-29-7) is a useful research chemical.

Applications 1,3,6,8-Tetrabromopyrene is used as a reactant in the synthesis of pyrene-centered starburst oligofluorenes which display good film forming ability and sky blue fluroescence and used in electroluminescent devices.
References Liu, F., et al.: Macromol. Rapid Comm., 29, 659 (2008);

Applications 2-Amino-1-(4-trifluoromethoxyphenyl)ethanone Hydrochloride is a reagent for the preparation of 4-phenylimidazole-2-thiones as tyrosinase inhibitors, their pharmaceutical and cosmetics compositions for the treatment or the prevention of the pigmentary disorders.
References Boiteau, J. G., et al.: From Fr. Demande (2008), FR 2917087 A1 20081212

Applications 4-Borono-2-(trifluoromethyl)benzoic acid

Applications 2-Fluoro-4-hydroxyphenylboronic acid

Applications 5,6-dibromonicotinic acid (cas# 29241-64-3) is a useful research chemical.

Applications 1-(2-Chloro-3-fluorophenyl)ethanone was used to prepare novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
References Steinig, A., et al.: Bioorg. Med. Chem. Lett., 23, 4381 (2013)

Applications 3-Bromo-2,6-dihydroxybenzoic Acid (cas# 26792-49-4) is a compound useful in organic synthesis.
References Norman, M., et al.: J. Med. Chem., 39, 1172 (1996),

Applications 1,2-Difluorobenzene is used in electrochemical analysis of transition metal complexes. 1,2-difluorobenzene is also a potent inhibitor of NMDA receptor.
References O'toole, T.R. et al.: Inorg. Chem., 28, 3923 (1989); Eger, E.I. et al.: Anesth. Analg., 102, 1397 (2006);