Organic Halides

<p>Applications 6-Bromohexanoic Acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosen, D. B., et al.: PCT Int. Appl. (2020), WO 2020254617 A1<br></p>

<p>Applications (2,3-Dichloro-4-oxyphenyl)-2-thienylmethanone (cas# 40180-03-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-one is an intermediate used to prepare aminothiazoles as therapeutic leads for prion diseases. It is also used in the synthesis of pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.<br>References Gallardo-Godoy, A., et al.: J. Med. Chem., 54, 1010 (2011); Keith, J., et al.: Bioorg. Med. Chem. Lett., 17, 2603 (2007)<br></p>

<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>

<p>Applications 4-(Bromomethyl)-2-fluorobenzonitrile is a useful building block for the preparation and optimization of the highly selective GLUT1 inhibitor, BAY-876.<br>References Siebeneicher, H., et al.: ChemMedChem, 11, 2261-2271 (2016);<br></p>

<p>Applications 1-Bromopentadecane is a building block that has been used in the preparation of 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromide as antibacterial and antioxidant agents.<br>References Kahriman, N., et. al.: Eur. J. Med. Chem., 69, 348 (2013)<br></p>

<p>Applications 3-​Amino-​5-​bromobenzotrifluorid​e is a general chemical reagent used in the synthesis of is a general chemical reagent used in the synthesis of trifluoromethylphenyl derivatives of methylguanidines as PET radioligands.<br>References aumiec, G. et al.: J. Med. Chem., 58, 9722 (2015);<br></p>

<p>Applications 9-Fluorenylmethyl tosylate is a useful reagent in the synthesis of Se-​(9-​Fluorenylmethyl) selenoesters and amino thioacids.<br>References Crich, D., et al.: Org. Lett., 9, 4423-26 (2007); Fecourt, F., et al.: Org. Lett., 15, 3758-61 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications O-Acetylsalicyloyl chloride is used in the derivatisation of amines, and also improve electrochemical detection of these amines when they are run through high-performance liquid chromatography. O-Acetylsalicyloyl chloride is also used as a reagent to synthesize benzimidazole derivatives, compounds that inhibit leukotriene synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Banoglu, E., et al.: Bioorg. Med. Chem., 20, 3728 (2012); Smith, R., et al.: J. Chromatogr. A, 455, 349 (1988)<br></p>

<p>Applications 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propionyl chloride, rech grade<br></p>

<p>Applications 2-Amino-5-chloro-4-fluoro-benzoic acid (cas# 351367-77-6) is a useful research chemical.<br></p>