Toxicology

<p>Applications A vasodilator.<br>References Varga, J., et al.: Mol. Immunol., 28, 641 (1991), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005),<br></p>

<p>Applications Dichlorobenzenamine is used in the synthesis of effective inhibitors of plant δ1-pyrroline-4-carboxylate reductase. Also used in the preparation of anti-tumor agents based upon diaryl urea derivatives.<br>References Forlani, G. et al.: J. Agri. Food Chem., 61, 6792 (2013); Zhai, X. et al.: Molecules, 18, 2904 (2013);<br></p>

<p>Stability Hygroscopic<br>Applications Pirlimycin Hydrochloride (Mixture of Diastereomers) is a semi-synthetic lincosaminide antibiotic; structural analog of Clindamycin. Antibacterial.<br>References Ahonkhai, V.I., et al.: Antimicrob. Agents Chemother., 21, 902 (1982); Qadri, S.M.H., et al.: J. Antibiot., 36, 42 (1983); Birkenmeyer, R.D., et al.: J. Med. Chem., 27, 216 (1984);<br></p>

<p>Applications Fluoxetine (F597100) derivative.<br>References Cashman, J. et al.: Bioorgan Med. Chem. 17, 337 (2009)<br></p>

<p>Applications Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wiseman, E., et al.: Biochem. Pharmacol., 21, 2323 (1972), Schmid, J., et al.: Drug Metab. Dispos., 23, 1206 (1995), Marnett, L., et al.: J. Biol. Chem., 274, 22903 (1999), Ji, T., et al.: Chem. Res. Toxicol., 20, 701 (2007),<br></p>

<p>Applications Dexmedetomidine is an α2-Adrenergic agonist; (+)-isomer of Medetomidine; sedative; analgesic.<br>References Rajala, R., et al.: Eur. J. Pharm. Sci., 1, 219 (1994), Jalonen, J., et al.: Anesthesiology, 86, 331 (1997), Talke, P., et al.: Anesth. Analg., 85, 1136 (1997), Bhana, N., et al.: Drugs, 59, 263 (2000),<br></p>

<p>Stability Light Sensitive<br>Applications trans-Permethrinic acid is a potent insecticide used in the agricultural industry to eliminate unwanted pests from crops. trans-Permethrinic acid is also metabolite of pyrethroid compounds, a group of pesticides that are relatively low toxicity (to organisms that are not intended to be targeted) and biodegradable.<br>References Kale, M., et al.: Toxicol. Lett., 105, 197 (1999); Leszczynski, J., et al.: J. Am. Chem. Soc., 115, 5891 (1993); Sodurlund, D. &amp; Bloomquist, J.: Ann. Rev. Entomol., 34, 77 (1989)<br></p>

<p>Applications Isotope labelled (+)-Isomenthone is an isomer of (-)-Menthone. (-)-Menthone is a constituent of the essential oils of pennyroyal, peppermint, Pelargonium geraniums, and others. It is also a naturally occurring pesticide.<br>References Zhang, Q., et al.: Pest Management Science, 69, 542 (2013); Weimin, Y., Shijie Nongyao, 30, 33 (2008);<br></p>

<p>Stability Hygroscopic<br>Applications Analgesic (narcotic). Controlled substance (opiates).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gruber, G.M., et al.: J. Pharmacol. Exp. Ther., 99, 312 (1950), Abdel-Monem, M.M., et al.: J. Med. Chem., 15, 494 (1972),<br></p>

<p>Stability Hygroscopic<br>Applications Hydrochloride Salt of 2-Methyl-3-isothiazolone-d3, a pesticidal substituted 3-isothiazolinone.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Thierse, H., et al.: J. Immunol., 172, 1926 (2004), Nilsson, A., et al.: Chem. Res. Toxicol., 18, 308 (2005), Nitsche, J., eet al.: J. Pharm. Sci., 95, 649 (2006),<br></p>

<p>Applications Streptozotocin is used in the treatment metastatic cancer of the pancreatic islet cells. Streptozotocin has a highlrisk of toxicity and is generally limited to cancers that are inoperable.<br>References Meyer, D.J. et al.: Am. J. Vet. Res., 37, 1221 (1976); Kouvaraki, M.A. et al.: J. Clin. Oncol., 22, 4762 (2004); Moore, A.S. et al.: Am. Vet. Med. Assoc., 221, 811 (2002):<br></p>

<p>Stability Light Sensitive<br>Applications Cannabigerorcin acts as a potential fungicide for use as a crop protection agent. Synthetic cannabinoid. Antimicrobial.<br>References Eisohly, H. et al : J. Pharm. Sci., 71, 1319 (2012); Tanaka, H. et al.: Forens. Sci. Int., 106, 135 (1999);<br></p>

<p>Applications Labelled Fludioxonil, nonsystemic phenylpyrrole fungicide structurally related to pyrrolnitrin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chang, C.-H., et al.: Biochemistry 30, 5352 (1991),<br></p>

<p>Applications Labelled Rupatadine (R701650). Rupatadine is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine is used as an antihistaminic.<br>References Merlos, M., et al.: J. Pharmacol. Exp. Ther., 280, 114 (1997), Guadano, E.M., et al.: Allergy, 59, 766 (2004),<br></p>

<p>Applications Fosetyl Aluminum is a fungicide. It is highly inhibitory in vitro against several species of Phytophthora.<br>References Fenn, M., et al.: Phytopathology, 74, 606 (1984); Matheron, M., et al.: Plant Disease, 84, 454 (2000)<br></p>

<p>Applications Zinc Thiozole is a fungicide.<br>References Domagalina, E., et al.: Fresenius' Zeitschrift fuer Analytische Chemie, 207, 411-14 (1965);<br></p>

<p>Stability Light Sensitive<br>Applications Carvone is useful for the treatment of various metabolic disorders and GI related disorders.<br>References Shabi, M. M., et al.: Res. J. Pharm. Biol. Chem. Sci., 8, 328 (2017)<br></p>

<p>Applications Octyl Decyldimethyl Ammonium Chloride is used as a wood preservative and sanitizing agent against bacterium on high density polyethylene surfaces.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yang, H. et al.: J. Food Prot., 72, 990 (2009); Butcher, J. et al.: Forest Prod. J., 27, 19 (1977);<br></p>