Toxicology

<p>Applications Prosulfuron is one of the 309 mostly pesticide active chemicals.<br>References Judson, R., et al.: Environ. Health Perspect., 118, 485 (2010).<br></p>

<p>Applications Labelled Mecoprop (M203052). Herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gagne, F., et al.: Environ. Res., 103, 238 (2007), LaChapelle, A., et al.: Reprod. Toxicol., 23, 20 (2007),<br></p>

<p>Applications A metabolite of Duloxetine.<br>References Lantz, R.J., et al.: Drug Dispos. Metab., 31, 1142 (2003), Detke, M., et al.: J. Clin Psy., 63, 308 (2002), Bymaster, F.P., et al.: Bioorg. Med., Chem. Lett., 13, 4477 (2003),<br></p>

<p>Applications Fenchlorphos-D6 is a labelled analogue of Fenchlorphos (F247402). Fenchlorphos is an organophosphorus pesticide that is used to maintain pest control. Fenchlorphos is highly toxic, and is known to exhibit toxic effects on animals such as rats.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Curini, M., et al.: Talanta, 27, 45 (1980); Johnson, W. &amp; Langford, G.: J. Econ. Entomol., 53, 477 (1960); McCollister, D., et al.: J. Agr. Food Chem., 7, 689 (1959); Sulinski, A., et al.: Neuro. Pols., 14, 451 (1976)<br></p>

<p>Stability Hygroscopic<br>Applications Labelled Amisulpride (A633250). Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>

<p>Applications 2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates.<br>References Laha, J. K.; et al.: J. Org. Chem., 82, 7346 (2017).<br></p>

<p>Stability Hygroscopic<br>Applications Ractopamine-d5 Hydrochloride is the isotope labelled analog of Ractopamine Hydrochloride (R071400); a β-adrenergic agonist and repartitioning agent.<br>References Eisemann, J.H., et al.: J. Nutr., 128, 504 (1998); Shelver, W.L., et al.: J. Agric. Food Chem., 48, 4020 (2000); Apple, J.K., et al.: J. Anim. Sci., 86, 2711 (2008)<br></p>

<p>Applications Spinosyn D is a potent insecticide for pathogens of crops.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light Sensitive<br>Applications Amidotrizoic Acid Dihydrate is used as a density gradient reagent for blood cell seperation. Diagnostic aid (radiopaque medium).<br>References Kalmer, J.R., et al., J. Immunol. Methods, 110, 275 (1988), Wang, Y., et al.: Br. J. Radiol., 170, 1229 (1997), Wong, V., et al.: Eur. J. Pharmacol., 433, 135 (2001).<br></p>

<p>Applications Nonsteroidal anti-inflammatory agent (NSAID).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>

<p>Applications Labelled Nizatidine. Histamine H2-receptor antagonist related to Ranitidine (R120000). Antiulcerative.<br>References Callaghan, J.T., et al.: Clin. Pharmacol. Ther., 37, 162 (1985), Secor, J.W., et al.: Br. J. Clin. Pharmacol., 20, 710 (1985), Knadler, M.P., et al.: Drug Metab. Dispos., 14, 175 (1986), Wozniak, T.J., et al.: Anal. Profiles Drug Subs., 19, 397(1990)<br></p>

<p>Applications A by-product of Fluorescein.<br>References Ames, B., et al.: Mutation Res., 31, 347 (1975),<br></p>

<p>Applications A new benzodiazepine derivative as a new anti-anxiety drug. Ethyl Loflazepate and its metabolite were compared with those of Diazepam (D416855), Nitrazepam (N490140) and Lorazepam (L469850). The anticonflict effect of Ethyl Loflazepate was slightly more potent than that of Diazepam and much more potent than that of Lorazepam. Controlled substance.<br>References Cano J.P., et al.: J. Chromatogr., 226, 413 (1981), Tanaka M., et al.: Clin. Neuropharmacology, (1985), 8,  271 (1985),<br></p>

<p>Applications β-(4-Chlorophenoxy)-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol is a agricultural fungicide that is systemically active against powdery mildews and rusts of grains.<br>References Echeverria-Saenz, S., et al.: Sci. Total. Environ., 440, 106 (2012); Hrouzkova, S., et al.: Int. J. Environ. Anal. Chem., 92, 1546 (2012); Loos, M., et al.: Environ. Sic. Technol., 46, 9830, (2012);<br></p>

<p>Applications Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.<br>References Barchas, et al.: Nature, 214, 919 (1967), Glass, J.D., et al.: Science, 214, 821 (1981),<br></p>

<p>Applications A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sadhale, P.P., et al.: J. Biol. Chem., 279, 33716 (2004), Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006),<br></p>

<p>Applications 3-Hydroxystearoylcarnitine Hydrochloride is found in overweight patients.<br>References Rodriguez-Gutierrez, R., et. al.: J. Int. Society Sports Nutrition, 9, 22, (2012)<br></p>