
Toxicology
Found 13550 products of "Toxicology"
Isolopinavir
CAS:Controlled ProductApplications Isolopinavir is a metabolite of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral.
References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998); Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999); Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)Formula:C38H50N4O5Color and Shape:NeatMolecular weight:642.827(4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid(Dolutegravir Impurity)
CAS:Controlled ProductFormula:C14H16N2O6Color and Shape:NeatMolecular weight:636.823N4-Triazolyl Terconazole
Controlled ProductFormula:C26H31Cl2N5O3Color and Shape:NeatMolecular weight:532.462Chloroquine N-Oxide
CAS:Controlled ProductApplications Chloroquine N-oxide is a metabolite of Chloroquine (C379965), a standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ.
References Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),Formula:C18H26ClN3OColor and Shape:NeatMolecular weight:335.872(3R,4R,5R)-Ethyl 4-Acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate
CAS:Controlled ProductFormula:C16H28N2O4Color and Shape:NeatMolecular weight:312.4041R-Hydroxy-5-keto Tiamulin
Controlled ProductFormula:C28H47NO4SColor and Shape:NeatMolecular weight:493.7422-Methyl-3-(4-(3-methylbutan-2-yl)phenyl)propan-1-ol
Controlled ProductFormula:C15H24OColor and Shape:NeatMolecular weight:220.351Desfluoro Tedizolid Phosphate Ester
Controlled ProductFormula:C17H17N6O6PColor and Shape:NeatMolecular weight:432.327Emtricitabine Isopropyl Carbamate
Controlled ProductApplications Emtricitabine Isopropyl Carbamate is a derivative of Emtricitabine (E525000). Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner.
References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)Formula:C12H16FN3O5SColor and Shape:NeatMolecular weight:333.336Ampicillin Amino-benzeneacetaldehyde-N-butenoic Acid Methyl Ester
Controlled ProductFormula:C29H32N4O7SColor and Shape:NeatMolecular weight:580.652Eicosapentaenoyl Ethanolamide
CAS:Controlled ProductApplications Eicosapentaenoyl Ethanolamide inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes.
References Lucanic, M., et al.: Nature, 473, 226 (2011)Formula:C9H14ClNO5Color and Shape:NeatMolecular weight:251.6649-Chloro-6-cyclopropyl-2,2-difluoro-4-oxo-8-(piperazin-1-yl)-4,6-dihydro-2H-[1,3,2]dioxaborinino[5,4-c]quinolin-1-ium-2-uide
Controlled ProductFormula:C17H17BClF2N3O3Color and Shape:NeatMolecular weight:395.596Posaconazole Di-glucuronide (M5)
Controlled ProductFormula:C37H42F2N8O4•2(C6H9O7)Color and Shape:NeatMolecular weight:893.36454Sulfisoxazole Acetyl
CAS:Controlled ProductFormula:C13H15N3O4SColor and Shape:NeatMolecular weight:309.342-Mercaptobenzoic Acid Hydrazide
CAS:Controlled ProductFormula:C7H8N2OSColor and Shape:NeatMolecular weight:168.216Cloxacillin Thiol Carboxylate Benzathine
CAS:Controlled ProductFormula:C19H18ClN3O4S2·C16H20N2Color and Shape:NeatMolecular weight:692.29BCX 4430
CAS:Controlled ProductApplications BCX 4430 is an antiviral drug, an adenosine analog). It is developed by BioCryst Pharmaceuticals with funding from NIAID, originally intended as a treatment for Hepatitis C, but subsequently developed as a potential treatment for deadly filovirus infections such as Ebola virus disease and Marburg virus disease.
References Warren, T., et al.: Nature, 508, 7496 (2014); Kamat, S., et al.: Biochem., 52, 7366 (2013)Formula:C11H15N5O3·ClHColor and Shape:NeatMolecular weight:301.729
