Biochemicals and Reagents

<p>Gastrin-1 Rat.</p>

<p>Peptide Octanoyl-RWKFGGFKWR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Boc-LGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Purified native Human Myoglobin protein (Cardiac)</p>

<p>Haemagglutinin (HA) peptide YPYDVPDYA – HA Tag</p>

<p>RSV antibody was raised in mouse using fusion protein of RSV, types A and B as the immunogen.</p>

<p>H-LGKRGSKPK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LGKRGSKPK-OH is provided at greater that &gt;98% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LGKRGSKPK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LGKRGSKPK-OH at the technical inquiry form on this page</p>

<p>H-NYMNLGATL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-NYMNLGATL-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-NYMNLGATL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-NYMNLGATL-OH at the technical inquiry form on this page</p>

<p>Influenza B antibody was raised in mouse using a nuclear protein from the Singapore strain of influenza B as the immunogen.</p>

<p>Peptide Ac-ETFG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Angiotensin II is a peptide hormone that is secreted by the kidneys. It stimulates the release of aldosterone and causes vasoconstriction, leading to an increase in blood pressure. Angiotensin II is also involved in other physiological functions such as the regulation of fluid balance, electrolyte levels, and blood coagulation. The drug is used to treat congestive heart failure and high blood pressure. Sar1-Angiotensin II has been shown to inhibit transcriptional regulation by binding to the angiotensin receptor type 1 (AT1). This binding disrupts conformational changes in the receptor, preventing signal transduction from occurring and decreasing the activity of enzymes such as protein kinase A, which are needed for activation of transcription factors.</p>

<p>Lenalidomide is a thalidomide derivative that is used to treat multiple myeloma and anemia. This drug exerts immunomodulatory effects by altering cytokine production. Lenalidomide also directly inhibits the cullin ring E3 ubiquitin ligase complex.</p>

<p>Peptide H-NSILTETLHR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Lamin B1 (15-26) is derived from the nuclear envelope protein, Lamin B1 which plays a role in the regulation of epigenetic chromatin. The arginine residue at position 12 is isotopically labelled with carbon-13 (6) and nitrogen-15 (4).</p>

<p>Peptide derived from the Sialokinin neuropeptide which is involved in smooth muscle contraction. It is homologous to mammalian Substance P and was first identified in mosquito Ae. Aegypti.</p>

<p>Influenza B antibody was raised in mouse using Influenza B as the immunogen.</p>

<p>Ara h 3 is one of the major allergens from peanut (Arachis hypogaea) out of approximately 13 potentially important allergens described. The Ara h 3 allergen is recognised by serum IgE from approximately 45% of peanut allergy patients.The peanut (Arachis hypogaea) is a member of the legume (Leguminosae) family, which includes beans and peas. Ara h 3 belongs to the glycinin family of legume storage proteins (S11 plant storage proteins) and is extensively proteolytically processed. This peptide represents a trypic peptide of Ara h 3.</p>

<p>Peptide H-LCDSGELVAIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SGFSSVSVSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-FAKKFAKKFKKFAKKFAKFAFAF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Imiquimod is a toll-like receptor 7 agonist drug that is used for the treatment of genital warts, basal cell carcinoma and condyloma acuminata. This drug works by relieving and controlling wart production. Studies in mice have shown that this drug may induce cytokines such as interleukins. Imiquimod helps to increase apoptosis of diseased tissues and an infiltration of lymphocytes into tumor lesions.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>H-VLQNLLTIEER-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VLQNLLTIEER-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VLQNLLTIEER-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VLQNLLTIEER-OH at the technical inquiry form on this page</p>

<p>Peptide H-LSTSEIASHLPTK^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>IL-6 Mouse is a recombinant protein that belongs to the cytokine family. It has been shown to activate IL-6 receptor. This receptor is a member of the GPCR family and possesses seven transmembrane domains with a large extracellular loop between TM2 and TM3. The extracellular domain contains binding sites for two different classes of ligands, including peptides and proteins. IL-6 Mouse is an antibody against IL-6 receptor that can be used as a research tool in pharmacology, protein interactions, cell biology, or immunology.<br>IL-6 Mouse is produced by high purity process and it contains no detectable levels of endotoxin or pyrogens.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Ac-CKGPNVAAIVGGTVV-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CKGPNVAAIVGGTVV-NH2 is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CKGPNVAAIVGGTVV-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CKGPNVAAIVGGTVV-NH2 at the technical inquiry form on this page</p>

<p>Factor VIII antibody was raised in mouse using purified human factor VIII as the immunogen.</p>

<p>Peptide Met-Enkephalin is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Cell-penetrating peptides (CPPs) have the ability to cross cell membrane bilayers without causing lethal membrane damage. CPPs themselves can exert biological activity and can be formed endogenously, or alternatively they can enhance transport of different cargoes across cell membranes. Vascular endothelial-cadherin-derived peptide (pVec) is an amphipathic CPP, these are characterised by both hydrophobic and hydrophilic regions. The charged region interacts with the cell membrane, while the hydrophobic region causes membrane perturbation, enabling translocation. pVec is derived from vascular endothelial cadherin, which is able to cross the blood brain barrier. Peptide is labelled with an N-terminal 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.</p>

<p>This peptide sequence corresponds to the peptide bond between mammalian Lys6- (K6) linked Ub proteins- where (GG) corresponds to the C-terminus of the side chain appended Ub. K6-linked Ub chains have been liked to DNA damage response and to the E3 Ub ligase BRCA1. K6 chains have also been shown to be important for mitophagy. The RING-in-between-RING (RBR) E3 ligases RNF144A and RNF144B assemble K6-linked chains in vitro. The homologous to the E6AP carboxyl terminus (HECT) E3 ligase HUWE1 also assembles K6-linked chains in vitro.</p>

<p>Thyroglobulin protein is a target molecule that plays a crucial role in the synthesis and storage of thyroid hormones. It is a large glycoprotein that is produced by the thyroid gland and released into the bloodstream. Thyroglobulin protein has been shown to interact with various proteins, including β-catenin, which is involved in cell adhesion and signaling pathways. Monoclonal antibodies targeting thyroglobulin protein have been developed for diagnostic purposes in thyroid cancer patients. These antibodies can specifically bind to thyroglobulin protein, allowing for the detection of residual or recurrent thyroid cancer cells. In addition to its diagnostic applications, thyroglobulin protein has also been investigated as a potential therapeutic target. Monoclonal antibodies against thyroglobulin protein have demonstrated cytotoxic effects on thyroid cancer cells in preclinical studies. Furthermore, anti-mesothelin monoclonal antibodies conjugated with radioactive isotopes have shown promising results in targeted radiotherapy for mesothelioma. Th</p>

<p>Nicorandil is an ATP-dependent potassium channel activator. It activates mitochondrial ATP-dependent potassium (KATP) channels and inhibits the TLR4/MyD88/NF-κB/NLRP3 pathway, which reduces myocardial infarction-induced pyroptosis. Pyroptosis is an inflammatory cell death process that regulates cardiomyocyte loss after myocardial infarction. These findings suggest that nicorandil may be a potential therapy for ischemic heart disease due to its cardioprotective effects.</p>

<p>Peptide Ac-CVQHHRERKRASKSSKHSMS-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Duck liver-derived peptide 3 is a novel bioactive peptide with high antioxidant activity. The antioxidant activity is attributed to forming hydrogen bonds between their amino acid residues and free radical molecules. Duck liver-derived peptide 2 increases the activities and mRNA expression levels of intracellular antioxidant enzymes (SOD, CAT, and GSH-Px) in HepG2 oxidative damage cell models. Duck liver-derived peptide 3 can reduce the content of malondialdehyde (MDA) and reactive oxygen species (ROS) accumulation, thereby inhibiting intracellular oxidative damage. Duck liver-derived peptide 3 has the following activity: immunomodulation, ACE inhibitor, dipeptidyl peptidase IV inhibitor, and antioxidant. This peptide may be used in the research for food-derived bioactive peptides for modified-food development.Of the identified duck-liver derived peptides, this is the only peptide in this group that has a proposed site of action as a HLA class I histocompatibility antigen.</p>

<p>Peptide H-NSVVLGKKQRFHSWG-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.</p>

<p>Peptide Biot-YARAAARQARA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EL^AGIGILTV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-GAPVNISSSDLTGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Beta-2 Microglobulin, Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Beta-2 Microglobulin, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Sakamototide is phosphorylated by members of the 5'-adenosine monophosphate-activated protein kinase (AMPK) family of kinases as is therefore ideal for use in kinase assays to test the activity of AMPK family members. The AMPK family includes- salt inducible kinases (SIKs), NUAK, sucrose non-fermenting (Snf1)-related kinase (SNRK), microtubule affinity regulating kinases (MARKs) and brain specific kinase/BR serine/threonine kinase (BRSK). The kinase activity of AMPK and AMPK-related kinases, is dependent on its phosphorylation at Thr175 by the upstream kinase LKB1 (also known as STK11).</p>

<p>Syntide-2 is a substrate peptide which was specifically designed to be homologous to site 2 in glycogen synthase. Syntide-2 is therefore phosphorylated by Ca2+ calmodulin-dependent protein kinase II as well as other calcium dependant kinases and protein kinase C. Synthase-2 can also be phosphorylated by CAMP-dependent protein kinase and to a lesser extent- phosphorylase kinase, but not by myosin light chain kinase.</p>

<p>Peptide H-ATLTLVSQETR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>SARS-CoV-2 Membrane protein (172-188)</p>

<p>Peptide H-KVLEYVIKV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SRTPSLPTPPTREPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Ac-CTRLFEQKLDIGARYS-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CTRLFEQKLDIGARYS-NH2 is provided at greater that &gt;85% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CTRLFEQKLDIGARYS-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CTRLFEQKLDIGARYS-NH2 at the technical inquiry form on this page</p>