Biochemicals and Reagents

<p>Peptide H-EQVTNVGGAVVTGVTAVAQK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>EDNRB antibody was raised in sheep using C-terminal peptide KANDHGYDNFRSSNN of rat ET(B) Receptor corresponding to amino acids 424 to 437 conjugated to KLH as the immunogen.</p>

<p>BX471 hydrochloride is a selective antagonist of the C-C chemokine receptor type 1 (CCR1), which is synthesized through rigorous chemical processes. It operates by inhibiting the binding of chemokines to the CCR1 receptor, thus interfering with the signaling pathways that lead to inflammation and immune responses. This mechanism is specifically effective in modulating immune system functions and controlling pathophysiological responses in various tissue types.</p>

<p>Adenovirus antibody was raised in mouse using hexon group antigen of many ADV serotypes as the immunogen.</p>

<p>R-(-)-Arundic acid is a chiral compound, which is a derivative of arundic acid specifically designed for enantiomeric purity. It is sourced through synthetic organic chemistry processes, allowing for precise control over its stereochemistry. The mode of action of R-(-)-Arundic acid involves the inhibition of astrocyte activation by modulating the synthesis of certain cytokines and inflammatory mediators. This mechanism provides a neuroprotective effect, making it a valuable tool in the study of neurodegenerative diseases and brain injuries.</p>

<p>Melatonin is a neurotransmitter produced by the pineal gland that is involved in the regulation of sleep-wake cycles. It can be used to treat several conditions like shift work disorders, insomnia, jet lag, and alterations of the circadian rhythm. Some authors also proposed the use of melatonin against cognitive disorders. In an interesting research conducted on zebrafish, it was found that memory formation occurs better during daytime compared to nighttime, suggesting a role of melatonin in this process. When melatonin was administered during the daytime it caused reduced memory formation. On the contrary, removing the pineal gland or treating the fish with a melatonin antagonist significantly improves nighttime memory formation.</p>

<p>H-Phe-Trp-OH is an inhibitor of protein phosphatase 2A and is used in the diagnosis of kidney cancer. Magnetic resonance spectroscopy (MRS) is a technique that can be used to measure the concentration of phosphate groups in tissues. Hypophosphatemia, or low phosphate levels in the body, is associated with a number of diseases, including kidney cancer. This molecule inhibits the activity of phosphatase 2A and can be used as a diagnostic marker for such conditions. The enzyme has been shown to have an inhibitory effect on vitamin D3-induced synthesis of calcitriol (1,25-dihydroxyvitamin D3), which may be due to its ability to sequester phosphate groups. H-Phe-Trp-OH binds to proteins and has been shown to have an inhibitory effect on other enzymes such as histidine phosphatase and glutamine phosphatase.</p>

<p>Purified Chicken IgG FITC conjugate</p>

<p>The rank ligand is a research tool for the study of protein interactions. It can be used to inhibit or activate ion channels, such as sodium channels and potassium channels. Rank ligands are small peptides that bind to receptors. The rank ligand is an inhibitor of the CAS No. 207621-35-0, which is an ion channel with a pore diameter of 0.2 nm in length and 0.3 nm in width that conducts sodium ions at a rate of 2 x 10^9 ions/s. <br>The rank ligand has high purity and can be used to study protein interactions involved in cell biology and pharmacology, as well as other life science applications such as biochemistry, genetics, and molecular biology.</p>

<p>Insulin antibody was raised in mouse using human insulin as the immunogen.</p>

<p>Peptide H-ARTKQTARKSTGGKAPRKQLA^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-KGSTAENAEYLRV-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Acid Red 357 is a basic dye, which is used in the treatment of wastewater. It binds to the surface of particles and reacts with sodium carbonate to form a hydroxide precipitate. This reaction leads to removal of colorants from the water. Acid Red 357 is also reactive, nucleophilic, and has high values for both kinetic data and transfer mechanism.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Fibrinopeptide B is a peptidic, biologically active peptide with the sequence Glu-Lys-Arg-Val. It is an epitope of the fibrinogen protein and has been reported to be involved in various biological processes such as cell proliferation, inflammation, and coagulation. Fibrinopeptide B is also a mass spectrometry standard for calibrating mass spectrometers. Biochemicals such as peptides and proteins can be identified by using this peptide. Fibrinopeptide B may also play a role in cancer metastasis and atherosclerosis.</p>

<p>S100 antibody was raised in mouse using human brain S-100 protein as the immunogen.</p>

<p>Inhibitor of VEGF receptors</p>

<p>Purified Sheep IgG HRP conjugate</p>

<p>AP 1903 is a synthetic small molecule, which acts as a dimerizer ligand. It is derived from the modification of the macrolide antibiotic rapamycin to remove its immunosuppressive effects, thus enabling targeted control of cellular processes. The mode of action involves binding to engineered receptors on the cell surface that contain drug-dependent domains. This binding triggers the dimerization of these receptors, leading to downstream signaling and subsequent cellular responses.</p>

<p>Des-n-Octanoyl-[Ser3]-Ghrelin (Human, 1-14) is a non-Acylated Analog of Ghrelin (Human, 1-14), amino acids 1-14 of the peptide hormone Ghrelin. This peptide does not contain the unique N-octanoyl group which is linked to Ghrelin's third serine residue covalently and which allows Ghrelin to associate with the growth hormone secretagogue receptor (GHS-R). Through interaction with the GHS-R, Ghrelin can exert its various effects on the body such as stimulating appetite, nutrient sensing, meal initiation and the regulation of insulin resistance, diabetes and obesity. Its wider functions are also associated with glucose homeostasis, energy homeostasis, cardio-protective effects, bone metabolism and its potential to be a target for cancer means that it can be used to develop therapies for a whole spectrum of diseases. This molecule is used as a research tool for studying cell biology and pharmacology.</p>

<p>Formyl peptide receptor-1 (FPR-1) antagonist</p>

<p>Mouse monoclonal CYP2B1B2 antibody</p>

<p>EGFR protein is a monoclonal antibody that targets the epidermal growth factor receptor (EGFR). It has been shown to have a high affinity for EGFR and can effectively bind to it, inhibiting its activity. This protein plays a crucial role in cell signaling pathways, including cell proliferation, survival, and differentiation. By targeting EGFR, this monoclonal antibody can block the activation of downstream signaling molecules such as caspase-9 and chemokines, thereby preventing the progression of diseases associated with EGFR dysregulation.</p>

<p>H-IGPGGDGPGG-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-IGPGGDGPGG-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-IGPGGDGPGG-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-IGPGGDGPGG-OH at the technical inquiry form on this page</p>

<p>Conjugated Morphine-HRP hapten</p>

<p>Peptide H-DIDEVSSLLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DEAL^NNR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Androgen receptor (AR) antagonist</p>

<p>H-GVLYVGSKTKE-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-GVLYVGSKTKE-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-GVLYVGSKTKE-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-GVLYVGSKTKE-OH at the technical inquiry form on this page</p>

<p>ÎŽ opioid receptor agonist; anti-nociceptive; anti-depressant</p>

<p>Purified Rat IgG (Fab'2) HRP conjugate</p>

<p>Anastrozole is a non-steroidal drug that belongs to the class of aromatase inhibitors. It inhibits the production of estrogen by blocking the conversion of androgens to estrogens in peripheral tissues. The drug has been shown to be effective in treating breast cancer in postmenopausal women. In vitro assays have shown that Anastrozole can inhibit tumor growth as well as induce apoptosis in human serum cells, which suggests that it may be effective against a variety of cancers.</p>

<p>Peptide H-TLAQLNPESSLFIIASK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-TARKSTGGC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Rhod-VPMLKE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-IQSFLGGAPTEDLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Neisseria Gonorrhoeae Antibody is a monoclonal antibody known as trastuzumab that specifically targets Neisseria gonorrhoeae, the bacteria responsible for causing gonorrhea. This antibody is designed to bind to specific antigens on the surface of the bacteria, leading to their destruction by the immune system. It has been shown to be effective in neutralizing the bacteria and preventing their growth and spread. This antibody can be used in diagnostic tests to detect the presence of Neisseria gonorrhoeae in human serum samples. Additionally, it can be conjugated with streptavidin or other molecules for use in research applications such as immunohistochemistry or flow cytometry. The Neisseria Gonorrhoeae Antibody offers a reliable and accurate tool for the detection and study of this common sexually transmitted infection.</p>

<p>Encequidar is a small-molecule inhibitor, which is a synthetic chemical compound with the ability to modulate the activity of efflux transporters. It specifically targets P-glycoprotein (P-gp), an ATP-binding cassette transporter widely expressed in tissues such as the intestine, kidney, liver, and blood-brain barrier. By inhibiting P-gp, Encequidar enhances the oral bioavailability of co-administered therapeutic agents that are typically P-gp substrates, thereby improving their systemic absorption and therapeutic efficacy.</p>

<p>Fmoc-His(Trt)-Wang Resin (100-200 mesh) 1% DVB is a resin for peptide synthesis that contains Fmoc-His(Trt) and 1% DVB. It is used to synthesize peptides with Fmoc chemistry.</p>

<p>BMP7 is a protein that belongs to the TGF-β superfamily. It is a potent inhibitor of bone resorption in vitro and in vivo. BMP7 also has been shown to inhibit the synthesis of collagenase and other proteases by osteoclasts, leading to decreased bone resorption. This protein activates receptors for insulin-like growth factor and activin, which are proteins produced by bone cells (osteoblasts) that regulate bone formation. BMP7 can also be used as a research tool for studying receptor activation, ligand binding, or ion channel function.</p>

<p>Diflunisal is a nonsteroidal anti-inflammatory drug (NSAID), which is a synthetic derivative of salicylic acid. It is primarily sourced through chemical synthesis rather than extraction from natural elements. Diflunisal functions by inhibiting the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which play a crucial role in the biosynthesis of prostaglandins. This inhibition results in reduced production of prostaglandins, compounds involved in inflammation and pain signaling pathways.</p>

<p>H-LLWTLVVLL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LLWTLVVLL-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LLWTLVVLL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LLWTLVVLL-OH at the technical inquiry form on this page</p>

<p>HSV 1/2 antibody was raised in mouse using HSV1/2 as the immunogen.</p>

<p>Penicillin Antibody is a monoclonal antibody that specifically targets and neutralizes the effects of penicillin. It is widely used in the field of life sciences for various applications. This antibody has been extensively tested and validated using luciferase assays, electrochemical impedance spectroscopy, and other techniques. It has been shown to effectively bind to penicillin molecules, preventing their interaction with target receptors and inhibiting their biological activity. Additionally, Penicillin Antibody has been found to reduce the levels of interleukin-6 (IL-6) and cortisol concentration in test subjects, indicating its potential as an anti-inflammatory agent. With its high specificity and potency, this antibody offers a valuable tool for researchers studying penicillin-related phenomena in both academic and industrial settings.</p>

<p>A highly potent antagonist of group II metabotropic glutamate receptors (IC50 values = 21 nM and 14 nM at human mGluR2 and mGluR3 respectively). LY 341495 also inhibits group I and III mGluRs with lower potencies (IC50 values = 0.17, 7.8 and 8.2 µM at mGluR8, mGluR1a and mGluR5a respectively). There has been contradicting findings on the antidepressant and anxiolytic activities of this compound. Enhanced cognitive function and locomotor activity have also been described for LY 341495.</p>

<p>VEGFR2 a tyrosine kinase receptor inhibitor; antineoplastic</p>

<p>H-ISQGTSGGAT-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ISQGTSGGAT-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ISQGTSGGAT-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ISQGTSGGAT-OH at the technical inquiry form on this page</p>

<p>Peptide LCBiot-PSQGKGRGLSLSRFSWGALTLGEFLKL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>RIPK2 protein kinase inhibitor; EGFR inhibitor</p>