Biochemicals and Reagents

<p>Peptide H-VTSIQDWV^QK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Ac-GAGVARGGAGGGPSGD-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-GAGVARGGAGGGPSGD-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-GAGVARGGAGGGPSGD-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-GAGVARGGAGGGPSGD-OH at the technical inquiry form on this page</p>

<p>Fmoc-γ-Abu-OH is a fatty acid that belongs to the group of neurotrophic factors. It has been shown to have neuroprotective properties in vitro and in vivo, and its mechanism may be related to its inhibition of apoptotic cell death. Fmoc-γ-Abu-OH also has pharmacokinetic properties, which are dependent on the route of administration. This compound is absorbed through the gastrointestinal tract and distributed throughout the body with a half-life of approximately 12 hours. Fmoc-γ-Abu-OH binds to β-catenin and inhibits its degradation by proteasomes, thereby increasing its levels in cells.</p>

<p>Fmoc-D-Glu(OtBu)-OH is an amino acid that is used in peptide synthesis. It can be used as a building block or as a tool for peptide synthesis. Fmoc-D-Glu(OtBu)-OH has the following characteristics:</p>

<p>Boc-D-Pro-OH is a model compound for the synthesis of peptides. Boc-D-Pro-OH has been used in many surface-enhanced Raman spectroscopy studies to investigate the stereochemistry of glycosidic bonds. It has also been used in pharmacokinetic studies to investigate the drug's absorption, distribution, metabolism, and excretion (ADME) properties. The solute is soluble in water due to its hydrophilic nature. Boc-D-Pro-OH is an enantiomer of Boc-L-Pro-OH and a functional group that contains a trifluoromethyl group. This chemical can be used in Tools for Peptide Synthesis with other compounds to form peptides with specific amino acid sequences.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Anti-Per3 antibody</p>

<p>Peptide H-NEALIALLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>6-Thioguanine is a purine analog used in the therapy for leukemia and for remission consolidation in patients with acute nonlymphocytic anemia. This drug also has antimetabolite action. It replaces guanine during DNA replication. This substitution disrupts the accurate pairing of DNA bases, leading to errors in DNA replication and hinders cell division.</p>

<p>Peptide H-IPLNDLFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>CGRP (Rat) product with the disulfide Bonds: Cys2-Cys7 and available as a 0.1 mg vial. CGRP is the calcitonin gene-related peptide (CGRP), a neuropeptide that plays an important role in the regulation of vascular tone and blood flow, as well as pain perception, inflammation, and neurogenic inflammation. It is a potent vasodilator and has been implicated in a wide range of physiological and pathophysiological processes.<br>This product has the potential for use in the study of the physiological and pathological roles of CGRP and to investigate the effects of CGRP on blood vessels, neurons, and other tissues. It has also been used to develop models of migraine headaches and other conditions associated with CGRP dysfunction.</p>

<p>Larazotide acetate is a drug that inhibits the activity of zonulin, a protein found in the intestines and believed to be involved in the regulation of tight junctions between cells. Larazotide acetate has been shown to reduce symptoms and disease activity in patients with inflammatory bowel disease (IBD). In a study involving human proteins, larazotide acetate was found to bind to actin filaments, which may have implications for its pharmacological use. Larazotide acetate has been shown to inhibit protease activity in various non-clinical studies. This drug is being developed as a potential treatment for autoimmune diseases and other inflammatory diseases.</p>

<p>Peptide H-SGEATDGARPQAL^PEPMQESK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-CLLAQAEGEPSYIRDSGV-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-CLLAQAEGEPSYIRDSGV-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-CLLAQAEGEPSYIRDSGV-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-CLLAQAEGEPSYIRDSGV-OH at the technical inquiry form on this page</p>

<p>H-CLESIMNTLES-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-CLESIMNTLES-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-CLESIMNTLES-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-CLESIMNTLES-OH at the technical inquiry form on this page</p>

<p>Fmoc-Phe-OH is a natural compound that has been shown to have antimicrobial properties. The biological properties of Fmoc-Phe-OH are not well understood, but it has been shown to have anticancer effects in some cases and to inhibit axonal growth when combined with the protein laminin. Fmoc-Phe-OH can be synthesized by the reaction of pheine with trifluoroacetic acid followed by treatment with h9c2 cells. The analytical method for determining the concentration of Fmoc-Phe-OH is based on intramolecular hydrogen exchange between hydrogen atoms on the amide group and hydrogens on neighboring methylene groups. This process releases heat, which is detected by a thermometer.<br>END&gt;</p>

<p>Luteinizing Hormone (LH) Mouse Monoclonal Antibody is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Luteinizing Hormone (LH) Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>CA-074 is a research tool that can be used to study protein interactions. CA-074 is a small, synthetic peptide and a potent inhibitor of the ion channel TRPC1. It has been shown to inhibit the calcium currents in HEK293 cells expressing TRPC1 channels. CA-074 inhibits the kinase activity of PLCγ2, which leads to reduced phosphoinositide levels and a decrease in cell proliferation. CA-074 also inhibits PKCδ and PKCε, which are members of the protein kinase C family.<br>The inhibition of these enzymes by CA-074 causes an increase in the intracellular concentration of diacylglycerol (DAG) and inositol triphosphate (IP3). These two molecules are involved in G protein signaling pathways that regulate cell proliferation, differentiation, and survival.</p>

<p>H-Ser-Leu-Ile-Gly-Lys-Val-NH2 is a synthetic peptide that is a cyclase inhibitor. It binds to the receptor for neurokinin 1, which has been shown to inhibit lacrimal gland function in rats. The compound also inhibits the synthesis of epidermal growth factor and has been shown to have anti-inflammatory effects in mouse models. H-Ser-Leu-Ile-Gly-Lys-Val-NH2 has also been shown to inhibit protease activity in rat prostate cells and can be used as a chemical inhibitor for proteases.</p>

<p>Boc-Ala-OH is a peptide that is used in the treatment of skin cancer. It has been shown to have antitumor properties, as well as antiviral and antifungal effects. Boc-Ala-OH has been shown to inhibit proteolytic enzymes, such as collagenase and elastase, which are involved in the development of inflammatory diseases. This peptide also binds to human serum albumin with high affinity, which may be an important factor in its therapeutic effect. Boc-Ala-OH inhibits the enzyme activities of neutrophils by binding to their membranes and changing the permeability of these cells, which causes them to release cytotoxic granule contents. This peptide also inhibits squamous cell carcinoma and other types of cancerous cells.</p>

<p>Peptide 5TAMRA-QEPEPPEPFEYIDD-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>TBTU Reagent is a combination of two reagents that are used for peptide synthesis and purification. TBTU is an amide coupling reagent that reacts with the carboxyl group of an ester to form a reactive intermediate, which then reacts with the amino group of an amide. This reaction forms an amide bond between the carboxyl group of the ester and the amino group of the amide. TBTU Reagent has been used in vitro assays to measure pharmacological activities such as anti-inflammatory effects and antimicrobial effects. TBTU Reagent has also been used to prepare mouse monoclonal antibodies against toll-like receptor 4 (TLR4).</p>

<p>Peptide LCBiot-GRPRTTSFAE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Endoglin is a protein that is encoded by the ENG gene and is expressed in most tissues. It has been shown to be an antagonist of angiopoietin-1 and angiopoietin-2, which are proteins that regulate the growth of blood vessels and act as a tumor suppressor. Endoglin has also been found to be expressed in neoplastic cells, including cancer cells. The physiological role of endoglin is not well understood, but it may play a role in cell migration and invasion, angiogenesis, or other cellular functions.</p>

<p>H-NVYMLATTVSSK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-NVYMLATTVSSK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-NVYMLATTVSSK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-NVYMLATTVSSK-OH at the technical inquiry form on this page</p>

<p>Pan-class I phosphatidylinositide 3-kinase (PI3K) inhibitor (IC50 = 3, 33, 3 and 75 nM at catalytic subunits p110α, p110β, p110δ and p110γ respectively). Inhibits proliferation in several cancer cell lines, such as glioblastoma, breast and prostate cancer cells. Has synergistic anti-cancer effect in combination with MEK/ERK kinase inhibitor GDC-0973 (cobimetinib).</p>

<p>Peptide H-WRWYRGGRYWRW-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Glutaryl-Gly-Gly-Phe-AMC is a proteolytic peptide which is used in the study of the proteasome. It has been shown to have affinity for the proteasome, and can be used as a monoclonal antibody for both immunohistochemical analysis and two-dimensional electrophoresis. The peptide was sequenced and found to have no homology to any known protein or peptide. Glutaryl-Gly-Gly-Phe-AMC has been shown to bind specifically to β amyloid (Aβ) subunits in cell homogenates and cytosol, as well as nuclei in tissue sections from AD brain. In addition, it has been shown that this peptide can be fluorescently labeled with Alexa Fluor 488 or 594 dye for use in microscopy studies.</p>

<p>H-AAAIQTMSLDAER-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AAAIQTMSLDAER-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AAAIQTMSLDAER-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AAAIQTMSLDAER-OH at the technical inquiry form on this page</p>

<p>Peptide H-RAAAAAAR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Anti-TRPA1 antibody</p>

<p>Peptide H-VFDEFKPLVEEPQNLIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-YIGSRIGPGPGGRGD-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-YIGSRIGPGPGGRGD-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-YIGSRIGPGPGGRGD-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-YIGSRIGPGPGGRGD-OH at the technical inquiry form on this page</p>

<p>CA 19-9 protein is a biomarker that is commonly used in the diagnosis and monitoring of certain types of cancer, particularly pancreatic cancer. It is a glycoprotein that is produced by cancer cells and released into the bloodstream. CA 19-9 protein levels are elevated in individuals with pancreatic, colorectal, and other gastrointestinal cancers.</p>

<p>Peptide H-TTEPVSELLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Suc-Phe-Ala-Ala-Phe-pNA is an amino acid that is a substrate for the serine protease myroilysin. It is used in biochemical research to investigate the physiological function of myroilysin. Suc-Phe-Ala-Ala-Phe-pNA has been shown to be an irreversible inhibitor of myroilysin and inhibits enzyme catalysis.</p>

<p>Peptide H-TVLAVFGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Fmoc-Lys(Glucitol, Boc)-OH is a synthetic peptide that acts as an inhibitor of the ion channel TRPC3. It binds to the ligand-binding site of TRPC3, preventing activation by its natural agonist, lysophosphatidic acid (LPA). Fmoc-Lys(Glucitol, Boc)-OH can also be used as a research tool in pharmacology and cell biology. It has been shown to inhibit the growth of cancer cells. This product is available at a purity of &gt; 98%.</p>

<p>Irsogladine is a gastroprotective drug that is used for the treatment of GERD and gastric ulcers. This drug also has antioxidant properties. Irsogladine is a phosphodiesterase-4 inhibitor and increases levels of cAMP. It helps to prevent and heal damage to the stomach lining.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Camostat mesilate is a prodrug that is metabolized to the active form, pemastatin. It is used for the treatment of bowel disease and squamous cell carcinoma. Camostat mesilate inhibits the TNF-α receptor by binding to its response element in vitro and in vivo. The biological properties of camostat mesilate are due to its ability to inhibit TNF-α production by binding to the TNF-α receptor, thereby preventing activation of transcription factors such as nuclear factor kappa B (NFκB). In vitro assays have shown that camostat mesilate induces apoptosis in human carcinoma cell lines through inhibition of growth factor-β1. This drug has also been shown to be effective in treating viral infections, including HIV and herpes zoster.</p>

<p>CA-074 Me is a small molecule that binds to the receptor site of the ion channel. This binding triggers a conformational change in the ion channel, which leads to an influx of ions and an increase in membrane potential. CA-074 Me has also been shown to bind to peptide receptors and activate them, leading to similar effects on cell membranes as with ion channels. CA-074 Me is used for research purposes as it can be used as a tool for studying protein interactions and ligand-receptor binding. It is also often used as an antibody capture reagent. CA-074 Me is a research chemical that was synthesized by Hetero Drugs Limited (India) and has CAS No. 147859-80-1.END&gt;</p>

<p>Peptide H-RPFYSNAPQEIFIQQGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SGLSTGWTQLSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Echistatin is a natural product isolated from the venom of the snake Echis carinatus. It is an inhibitor of protein synthesis that binds to the integrin receptor and blocks the binding of extracellular matrix proteins, leading to cell death. Echistatin has been shown to inhibit the proliferation of human osteosarcoma cells in vitro and induce neuronal death in vivo. In addition, it has been shown to be effective against human breast cancer cells that express high levels of integrins. The disulfide bond in echistatin may represent a potential anticancer agent due to its ability to form covalent bonds with other molecules such as DNA, RNA, or proteins.</p>

<p>This product has disulfide Bonds between Cys1-Cys15 and Cys3-Cys11, is sourced from: Porcine, 1-39 and is available as a 0.1mg vial. Big Endothelin-1 (Porcine, 1-39) is a precursor peptide of the vasoconstrictor Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.<br>Overall Big Endothelin-1 (Porcine, 1-39) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.</p>

<p>Fmoc-Ser(tBu)-OH is a synthetic peptide that is used in the synthesis of peptides and proteins. It is synthesized by using a stepwise procedure, which involves the use of morpholine as an organic base to deprotonate the carboxylic acid group and then reacting it with trifluoroacetic acid (TFA) to form the corresponding chloroformate ester. The amide bond is formed by reaction with ammonia or an amine. Finally, it can be reacted with hydrochloric acid to form the corresponding hydrochloride salt, which is insoluble in water. Impurities such as thionyl chloride and chloroformate can be removed by washing with methylene chloride or chloroform, respectively. Fmoc-Ser(tBu)-OH has been shown to be selective for the formation of hydrophobic bonds between amino acids and is not reactive toward other side chains on the protein.</p>

<p>Peptide H-TIAQDYGVLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Antimicrobial peptide consisting of disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29. Alpha-defensin-4 is a small, cationic peptide that is part of the alpha-defensin family of antimicrobial peptides in humans. It is primarily produced by neutrophils, which are a type of white blood cell that plays a critical role in the immune response to bacterial infections.<br>Alpha-defensin-4 is known to have broad-spectrum antimicrobial activity against a wide range of bacterial pathogens, including both Gram-positive and Gram-negative bacteria. Like other alpha-defensins, alpha-defensin-4 achieves its antimicrobial activity by disrupting the cell membranes of the pathogens, leading to cell lysis and death.<br>In addition to its antimicrobial activity, alpha-defensin-4 has been found to have other functions in the body, including modulating the immune response and promoting tissue repair. It has also been implicated in the pathogenesis of certain inflammatory and autoimmune diseases, including rheumatoid arthritis and psoriasis.<br>Alpha-defensin-4 is typically found in various bodily fluids, including blood, urine, and semen, and its levels can be used as a diagnostic marker for certain conditions. For example, elevated levels of alpha-defensin-4 in joint fluid can be indicative of a bacterial infection in the joint, which can help to guide treatment decisions.</p>

<p>Amyloid Beta-Protein (40-1) is a peptide that is found in the brain, and is thought to be involved in Alzheimer’s disease. Amyloid Beta-Protein (40-1) has been shown to inhibit protein interactions and activator functions, as well as act as a ligand for receptors. This protein can be used as a research tool for studying ion channels and antibodies. It also has high purity and can be used for life science experiments.</p>