Biochemicals and Reagents

<p>Peptide H-GIYDGDLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-AAEGLDTQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VVAGVANALAHK^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Rabbit anti-Human IgG4 monoclonal antibody</p>

<p>Inhibitor of dopamine (D2) and serotonin (5HT2) receptors; anti-psychotic</p>

<p>Prolactin antibody was raised in mouse using purified human prolactin as the immunogen.</p>

<p>Salmonella antibody (LPS core) was raised in mouse using LPS core of Salmonella as the immunogen.</p>

<p>Influenza B antibody was raised in mouse using Influenza B as the immunogen.</p>

<p>Pemirolast is an antihistamine drug that is used for the treatment of allergies such as hay fever and allergic conjunctivitis. This drug binds to the histamine H1 receptor and blocks the action of histamine which results in the relief of allergic symptoms brought on by histamine. This drug is also a mast cell stabilizer.</p>

<p>Sheep Red Blood Cells (SRBC) are widely used in various research applications. SRBC contain prodigiosin, a red pigment that can be used as a marker for cell labeling and tracking. They are often used in studies involving messenger RNA (mRNA) analysis, electrophoresis, and the characterization of metal-binding proteins. In veterinary applications, SRBC can be used as an anticoagulant to prevent blood clotting during procedures. Additionally, SRBC have been utilized in studies related to adipose tissue, liver microsomes, midbrain dopaminergic neurons, interferon production, and the development of monoclonal antibodies with neutralizing properties. With their versatility and wide range of applications, SRBC are essential tools in life sciences research.</p>

<p>Anti-PDE2A3 antibody</p>

<p>BRDU antibody was raised in mouse using bromodeoxyuridine as the immunogen.</p>

<p>Influenza B antibody was raised in mouse using Influenza B as the immunogen.</p>

<p>Rabbit anti-mouse IgG2a (FITC) was raised in rabbit using murine IgG2a heavy chain as the immunogen.</p>

<p>VZV (early gene 62) antibody was raised in ouse using Varicella Zoster Virus HZ as the immunogen.</p>

<p>Nicotinic receptor antagonist</p>

<p>Inhibitor of ErbB2 (IC50 = 3 nM) and EGFR kinase (IC50 = 6.4 nM) with anti-proliferative effects. It inhibits ErbB2 receptor autophosphorylation and induces G1 cell cycle block. The CP 724714 treatment induces reduction of downstream ErbB2 receptor tyrosine kinase signalling, tumor cell apoptosis, release of caspase 3 and regression of tumors in in vivo and in vitro models.</p>

<p>14.3.3 Sigma antibody (BSA/Azide-free) was raised in mouse using recombinant human 14-3-3 sigma protein as the immunogen.</p>

<p>H-ALELLMAANFLDC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ALELLMAANFLDC-NH2 is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ALELLMAANFLDC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ALELLMAANFLDC-NH2 at the technical inquiry form on this page</p>

<p>Eotaxin is a human basic protein that belongs to the eosinophil cationic protein family. It stimulates the growth of cells and promotes tissue repair. Eotaxin also has a role in the immune response, as it is able to bind to and activate macrophages, neutrophils, and lymphocytes. Eotaxin is found in increased concentrations in inflammatory bowel disease (IBD), where it may play a role in the recruitment of inflammatory cells. The signal peptide sequence of eotaxin is cleaved by signal peptidase I and II during transit through the Golgi apparatus, yielding an active form that can be processed into mature eotaxin by several proteases. This active form can be detected by polymerase chain reaction (PCR) amplification of DNA isolated from human peripheral blood leukocytes or colonic biopsies. Eotaxin has been shown to have anti-inflammatory effects on both healthy tissues and those with</p>

<p>H-IEKTISKAKGQPREPQVY-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-IEKTISKAKGQPREPQVY-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-IEKTISKAKGQPREPQVY-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-IEKTISKAKGQPREPQVY-OH at the technical inquiry form on this page</p>

<p>Ac-SRPSPFDLFIRKSC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-SRPSPFDLFIRKSC-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-SRPSPFDLFIRKSC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-SRPSPFDLFIRKSC-NH2 at the technical inquiry form on this page</p>

<p>H-AFVTWHRYHLLWLER-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AFVTWHRYHLLWLER-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AFVTWHRYHLLWLER-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AFVTWHRYHLLWLER-OH at the technical inquiry form on this page</p>

<p>Mitochondria contain 4 multimeric electron transfer complexes (CI-CIV) that allow a stepwise transfer of electrons leading to energy production. The electron transfer complexes can form supercomplexes with a core of monomeric CI and dimeric CIII. The purpose of the supercomplex is believed to be direct electron transfer in a discrete unit with additional structural roles in the mitochondria. NDUFA11 is a conserved integral membrane protein that sits at the interface of CI and CIII. Lack of functional NDUFA11 leads to infant death, and encephalocardiomyopathy.</p>

<p>Salbutamol antibody was raised in mice using Salbutamol as the immunogen.</p>

<p>H-AWGNNQDGVVASQPAR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AWGNNQDGVVASQPAR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AWGNNQDGVVASQPAR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AWGNNQDGVVASQPAR-OH at the technical inquiry form on this page</p>

<p>Mouse monoclonal SLC7A8 antibody</p>

<p>Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used to reduce inflammation, relieve pain and reduce fever. The mechanism of action of ibuprofen has not been fully elucidated, but it may be due to inhibiting the enzyme cyclooxygenase and thus decreasing the synthesis of prostaglandins allowing a reduction of pain and inflammation.</p>

<p>Anti-UCP1 antibody</p>

<p>H-ARLSAWAIW-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ARLSAWAIW-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ARLSAWAIW-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ARLSAWAIW-OH at the technical inquiry form on this page</p>

<p>The Hepatitis E Virus protein is a recombinant protein that contains functional groups necessary for various applications in the field of Life Sciences. It can be used in industrial settings as well as in microbiological culture studies. This protein, specifically the orf2 protein, has been activated and can be utilized in immunoassays. It is commonly used with monoclonal antibodies to detect and study the presence of Hepatitis E Virus. With its high purity and quality, this recombinant protein offers reliable results and accurate analysis. Whether you are conducting research or developing diagnostic tools, the Hepatitis E Virus protein is an essential component for your experiments.</p>

<p>Cholera toxin antibody was raised in mouse using beta subunit of cholera toxin as the immunogen.</p>

<p>Anti-phospho-TDP-43 (pS409/pS410) antibody</p>

<p>Dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) acts as a central dissolvase of membraneless organelles during the G2-to-M transition. DYRK3 mediates the phosphorylation of multiple serine and threonine residues in unstructured domains of proteins, including SRRM1 and PCM1._x000D_<br>_x000D_<br>DYRK3 is a key regulator of mTORC1 by mediating the dissolution of stress granules. During stressful conditions, DYRK3 partitions from the cytosol to the stress granule with mTORC1 components, which prevents mTORC1 signalling. When homeostasis is achieved, the kinase activity of DYRK3 is required for the dissolution of stress granule and mTORC1 relocation to the cytosol. DYRK3 mediates phosphorylation of signalling mTORC1 via inhibitor AKT1S1, allowing full reactivation of mTORC1 signalling._x000D_<br>_x000D_<br>DYRK3 is a negative regulator of EPO-dependent erythropoiesis and may place an upper limit on red cell production during stress erythropoiesis. DYRK3 also inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells._x000D_<br>_x000D_<br>Overexpression of DYRK3 has been linked to glioblastoma multiforme (GBM) and can be a strong predictive factor of a patient's survival chances.</p>

<p>Normal Guinea Pig Serum is a veterinary product that is commonly used in various applications. It is known for its photostability and contains essential components such as glycan, human serum, glycoprotein, and glycosylation. This serum is activated and can be used in experiments involving farnesyl transferase and glycopeptide. Additionally, Normal Guinea Pig Serum is often utilized in the life sciences field for research purposes, including the development of monoclonal antibodies and chemokines. It is an important biospecimen that provides valuable insights into various biological processes.</p>

<p>PDEs are a family of phosphohydrolyases, used to catalyse hydrolysis of 3 €™ cyclic phosphate bonds in the second messengers adenosine and guanine 3 €™, 5 €™ cyclic monophosphates (cAMP and cGMP). Physiologically, PDE2A is a locus for communication between cAMP and cGMP signalling pathways, regulating this process through degradation of cAMP and cGMP. This is particularly noteworthy in cells where cAMP and cGMP regulate opposing cell functions.PDE2A is expressed both in the periphery and central nervous system, but is found in highest concentration in the brain; implying that PDE2A is necessary in regulation of interneuronal cAMP and cGMP involved in emotion, sensory perception and memory. Alteration in cyclic nucleotide signalling is shown cause depression, bipolar disorder and schizophrenia; hence PDE2A, a molecule used to break down cyclic nucleotides, has the potential to be a novel biomarker or therapeutic target for such psychiatric conditions.</p>

<p>Anti-UCP1 antibody</p>

<p>Lysozyme antibody was raised in sheep using human lysozyme as the immunogen.</p>

<p>Elastase antibody was raised in mouse using purified human neutrophil elastase as the immunogen.</p>

<p>HBsAg antibody (Subtype ad/ay) was raised in goat using hepatitis B surface antigen as the immunogen.</p>

<p>Ac-KIKSGERGRKGPGPGG-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-KIKSGERGRKGPGPGG-NH2 is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-KIKSGERGRKGPGPGG-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-KIKSGERGRKGPGPGG-NH2 at the technical inquiry form on this page</p>

<p>Streptococcus group A antibody was raised in rabbit using group A streptococci as the immunogen.<br>Streptococcus Group A (Strep A) is a type of bacteria known as Streptococcus pyogenes. It is a Gram-positive, beta-hemolytic bacterium that commonly causes infections in humans. Strep A can cause mild infections such as strep throat, scarlet fever, and impetigo, or severe infections namely cellulitis, necrotizing fasciitis, and sepsis.</p>

<p>H-VSQPTAEQAQAFK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VSQPTAEQAQAFK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VSQPTAEQAQAFK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VSQPTAEQAQAFK-OH at the technical inquiry form on this page</p>

<p>S26131 is an advanced glycation end product (AGE) inhibitor, which is a synthetic compound designed for laboratory research purposes. It is derived from chemical synthesis processes, offering a robust tool for investigating the biochemical pathways associated with glycation. Its mechanism of action involves the inhibition of AGE formation, which is a post-translational modification resulting from the non-enzymatic reaction between sugars and proteins or lipids. This biochemical modulation is vital for studying the implications of glycation in various physiological and pathological contexts.</p>

<p>Desipramine antibody was raised in mouse using Imipramine conjugated to KLH as the immunogen.</p>

<p>Inhibitor of S-adenosylhomocysteine hydrolase that disrupts histone methylation by EZH2. Anti-proliferative in some breast cancer and invasive prostate cancer cell lines. One of four key molecules required for inducing chemical reprogramming of somatic cells into induced pluripotent stem cells (iPSC).</p>

<p>Peptide H-NLFLNHSENATAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-WLISQNK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-WLISQNK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-WLISQNK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-WLISQNK-OH at the technical inquiry form on this page</p>

<p>Uroplakin III antibody was raised in mouse using AUM preparation from bovine urinary bladder as the immunogen.</p>

<p>The NGAL antibody is a highly specialized antibody that plays a crucial role in the field of Life Sciences. It specifically targets and binds to Neutrophil Gelatinase-Associated Lipocalin (NGAL), a protein that is expressed in various cells, including cardiomyocytes. The NGAL antibody is available in a dimer form and recognizes different isoforms of the NGAL protein.</p>