Antibiotics

Inhibitor of cell-wall synthesis; carbapenem class

Ceftizoxime sodium is a sodium salt form of ceftizoxime with similar action and applications as ceftizoxime.

D-Cycloserine is a antibiotic and NMDA receptor partial agonist with action on bacterial cell wall synthesis and modulation of NMDA receptors and is used for treating tuberculosis and studying neuropsychiatric disorders.

Tobramycin used to treat severe infections with gram-negative bacteria and it is often applied in combination with beta-lactams. It has similar antimicrobial effects to gentamicin and is effective against all Enterobacteriacae, but more effective than gentamicin against P. aeruginosa, which is why it is often used for gentamicin-resistant strains, especially in the case of cystic fibrosis.

Inhibits chaperone protein HSP90; anti-proliferative; antineoplastic

Monensin sodium is a polyether antibiotic with action on ion transport across bacterial cell membranes and is used for preventing coccidiosis and improving feed efficiency in livestock.

Rifaximin is a rifamycin antibiotic with action on bacterial RNA polymerase to inhibit transcription and is used for treating travelers' diarrhea, irritable bowel syndrome, and hepatic encephalopathy.

Maduramicin ammonium is an anticoccidial agent with action on protozoal parasites by disrupting ion gradients and is used for preventing coccidiosis in poultry.

β-lactam antibiotic of penicillin subclass, which inhibits bacterial cell wall synthesis by targeting the proteoglycan synthesis. Cloxacillin has a narrow spectrum of action and is effective against Gram-positive organisms. Cloxacillin is resistant to the action of β-lactamase and therefore preferentially used for treatment of Staphylococcal infections.

Sisomicin is an aminoglycoside antibiotic with action on bacterial protein synthesis inhibition and is used for treating severe bacterial infections resistant to other aminoglycosides.

Inhibitor of protein synthesis; aminoglycoside

Cephradine is a first-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating bacterial infections like urinary tract infections, respiratory infections, and skin infections.

Penicillin G potassium is a natural penicillin antibiotic with action on bacterial cell wall synthesis and is used for treating severe bacterial infections like meningitis, syphilis, and endocarditis.

Neospiramycin I is a macrolide antibiotic with action on bacterial ribosomes to inhibit protein synthesis and is used for treating bacterial infections in research applications.

Pefloxacin mesylate is a fluoroquinolone antibiotic with action on bacterial DNA gyrase and topoisomerase IV and is used for treating bacterial infections, including urinary and respiratory tract infections.

Amicoumacin B is a potent antibiotic, which is isolated from the bacterial species Bacillus pumilus. It acts by inhibiting protein synthesis, targeting the ribosomal 30S subunit and disrupting translational fidelity in bacterial cells. This interference in protein production leads to the effective elimination of various Gram-positive and certain Gram-negative bacteria.

Inhibitor of isoleucyl-tRNA synthetase; inhibitor of protein synthesis

Inhibitor of protein synthesis; lincosamide

Sulfasalazine is a disease-modifying anti-rheumatic drug (DMARD) with action on reducing inflammation and immune system activity and is used for treating rheumatoid arthritis and inflammatory bowel disease.

Ampicillin is a β-lactam antibiotic with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. It is used in the treatment of bacterial infections, including those caused by methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pneumoniae, and Listeria monocytogenes. Ampicillin binds to penicillin-binding proteins in the bacterial cell wall by competitive inhibition. It prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division.