Immunology Antibodies

CMV pp65 (Human, 495-503) is an immunogenic peptide, which is derived from the Human Cytomegalovirus (HCMV) phosphoprotein pp65. Also known as CEF20 or Cytomegalovirus pp65 (495-503), this peptide is a fragment of a viral protein known to play a significant role in the immune response to CMV infection. The source of this peptide is the viral protein itself, specifically a conserved region within it.The mode of action involves its recognition by cytotoxic T lymphocytes (CTLs), which are crucial for evaluating cellular immune responses in research settings. Researchers use it to monitor and study immune responses to HCMV, particularly in contexts involving immunocompromised individuals such as transplant recipients, where CMV infection poses significant risks.In applications, CMV pp65 (495-503) is primarily utilized in immunological studies, including T-cell assays and vaccine research, to better understand the dynamics of immune responses to CMV. Its role in scientific investigations is central to developing therapeutic strategies and diagnostic tools related to CMV and other related viral infections.

Purified Mouse IgG3 FITC conjugate

Aldehyde dehydrogenase antibody was raised in rabbit using aldehyde dehydrogenase isolated from yeast as the immunogen.

Arginase antibody was raised in rabbit using arginase isolated from bovine liver as the immunogen.

Fragment of the signal peptide from endogenous HLA Class I molecules which is also found in viral glycoproteins, for example human Cytomegalovirus (hCMV) protein UL40.  When presented on a cell surface via HLA-E molecules, the HLA-peptide complex binds NKG2A receptors on Natural Killer (NK) cells and some CD8⁺ cytotoxic T cells to reduce their cytotoxic activity. Blocking this interaction is an attractive opportunity for immune checkpoint (IC) approach therapies. This is relevant in both cancer therapies, and viral infections, where endogenous HLA Class I peptide presentation is exploited to escape immune attack.Peptide H-VMAPRTLL^-OH is a heavy-labeled version of PP45242, and is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Purified Human IgM protein (Fab mu)

Human IgM protein (Fab mu) (HRP) conjugate

HRP antibody was raised in goat using HRP as the immunogen.

Fragment of the signal peptide from endogenous HLA Class I molecules which is also found in viral glycoproteins, for example human Cytomegalovirus (hCMV) protein UL40.  When presented on a cell surface via HLA-E molecules, the HLA- VMAPRTLVL complex binds NKG2A receptors on Natural Killer (NK) cells and some CD8⁺ cytotoxic T cells to reduce their cytotoxic activity. Blocking this interaction is an attractive opportunity for immune checkpoint (IC) approach therapies. This is relevant in both cancer therapies, and viral infections, where endogenous HLA Class I peptide presentation is exploited to escape immune attack.In one study, VMAPRTLVL UL4015-23 was found in 18% congenital cytomegalovirus (cCMV) strains.

Goat IgG is a multispecific antibody that plays a crucial role in various biological processes. It is commonly used in life sciences research and immunoassays due to its high specificity and affinity for target antigens. Goat IgG has been shown to bind to a wide range of proteins, including β-catenin and nuclear factor kappa-light-chain-enhancer, thereby modulating their activity. Additionally, it has been found to activate polymerase activity and exhibit proteolytic effects on caspase-9, an endonuclease involved in apoptosis. As a result, Goat IgG is widely used in monoclonal antibody production, as well as in growth factor and acidic protein detection assays. With its diverse applications and reliable performance, Goat IgG is an essential tool for researchers in the field of Life Sciences.

Rat IgG is a monoclonal antibody that targets specific proteins and molecules in various biological processes. It is widely used in Life Sciences research, particularly in assays and experiments involving proteinase inhibitors, nuclear or extracellular markers, and growth factors. Rat IgG can bind to a variety of antigens, including sclerostin, erythropoietin, and bone morphogenetic protein. This purified immunoglobulin provides researchers with a reliable tool for studying the function and expression of these proteins in different cellular contexts. With its high specificity and affinity, Rat IgG is an essential component in many scientific investigations.

Acid Phosphatase antibody was raised in rabbit using acid phosphatase [Potato] as the immunogen.

Purified Human IgG Fab protein

Purified Rat IgG FITC conjugate

LDH antibody was raised in goat using full length lactate dehydrogenase protein isolated from rabbit muscle as the immunogen.

Purified Dog IgG (Fab'2)

Rabbit IgG (Fab) is a purified immunoglobulin that is commonly used in the field of life sciences. It is derived from adipose tissue and has been activated for optimal performance. This monoclonal antibody is specifically designed to target connexin, a protein involved in cell communication. By binding to connexin, Rabbit IgG (Fab) can block its function and disrupt intercellular signaling pathways. Additionally, this antibody has been engineered to deliver cytotoxic agents directly to cancer cells, making it an effective antibody-drug conjugate for targeted therapy. With its high affinity and specificity, Rabbit IgG (Fab) is a valuable tool for researchers studying cellular processes and developing new treatments for various diseases.

Carbonic anhydrase II antibody was raised in rabbit using carbonic anhydrase II from human Erythrocytes as the immunogen.

Biotin antibody (FITC) was raised in goat using biotin conjugated KLH as the immunogen.

Fragment of the signal peptide from endogenous HLA Class I molecules which is also found in viral glycoproteins, for example human Cytomegalovirus (hCMV) protein UL40. When presented on a cell surface via HLA-E molecules, the HLA- VMAPRTLLL complex binds NKG2A receptors on Natural Killer (NK) cells and some CD8⁺ cytotoxic T cells to reduce their cytotoxic activity. Blocking this interaction is an attractive opportunity for immune checkpoint (IC) approach therapies. This is relevant in both cancer therapies, and viral infections, where endogenous HLA Class I peptide presentation is exploited to escape immune attack. In one study, VMAPRTLLL UL4015-23 was found in 10% congenital cytomegalovirus (cCMV) strains.Peptide H-VMAPRTLL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.