Heterocycles with Nitrogen (N)

<p>Applications 2,3-Dichloropyrazine is a substrate used for an efficient synthesis of aloisine (A575450), a potent cyclin-dependent kinase.<br>References Chekmarev, D.S., et al.: Tetrahedron., 62, 9919 (2006);<br></p>

<p>Applications 4-​(4-​Amino-​3-​fluorophenoxy)​pyridine-​2-​carboxamide is a reagent used in the synthesis of heterocyclic urea derivatives as kinase inhibitors in the treatment of myeloproliferative and other diseases.<br>References Flynn, D. et al.: PCT Int. Appl. (2013), WO 2013036232 A2 20130314;<br></p>

<p>Applications B-[2-(Methylamino)-4-pyridinyl]boronic Acid Hydrochlroide, is used to prepare novel selective thiazoleacetic acids as CRTH2 antagonists.<br>References Grimstrup, M., et al.: Bioorg. Med. Chem. Lett., 20, 1181 (2010)<br></p>

<p>Applications 1,2-benzisoxazol-3-amine (cas# 36216-80-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications (4R,6R)-4-(2-Carboxyethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-4,6-dicarboxylic Acid, is an isomer of Mikimopine (M385508), which forms in roots after transformation with agrobacterium and influences alkaloid production. This in turn affects insect toxicity and allelopathic properties.<br>References Sauerwein, M. et al.: J. Plant Physiol., 142, 446 (1993);<br></p>

<p>Applications Piperazine-N,N'-bis(2-ethanesulfonic Acid)-d18 (CAS# 352534-95-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-(2-Pyridinyl)benzotriazole (cas# 13174-93-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(4-Bromophenyl)piperidin-2-one<br></p>

<p>Applications 2-Amino-4-chloro-3-nitropyridine (cas# 6980-08-1) is a compound useful in organic synthesis.<br>References Bavetsias, V., et al.: Bioorg. Med. Chem. Lett., 17, 6567 (2007), Niculescu-Duvaz, D., et al.: J. Med. Chem., 52, 2255 (2009),<br></p>

<p>Applications (4S)​- 5,​5-​Dimethyl-​2-​[[[(5-​methyl-​3-​phenyl-​4-​isoxazolyl)​carbonyl]​amino]​methyl]​-4-​thiazolidinecarboxyl​ic acid is a useful reactant.<br></p>

<p>Applications 1-Pyridin-2-yl-propan-2-one is an antimicrobial bioactive compound extracted from Lactarius vellereus fermenting liquor.<br>References Ji, H., et al.: Beijing Linye Daxue Xuebao, 30, 92 (2008); Song, R., et al.: From Faming Zhuanli Shenqing (2008), CN 101230368 A 20080730;<br></p>

<p>Applications 2,3-Diaminopyridine is used as a reagent in the synthesis of novel imidazopyridine derivatives which can exhibit cytotoxic activity against MCF-7 human breast adenocarcinoma cell line. 2,3-Diaminopyridine is also used in the preparation of non-camptothecin topoisomerase I inhibitors which exhibit antitumor activity.<br>References Puskullu, M.O., et al.: Chem. Heterocyc. Compd., 51, 723 (2015); Zhang, C., et al.: Bioorg. Med. Chem. Lett., 25, 4693 (2015)<br></p>

<p>Applications methyl 2-amino-5-benzyl-5,6-dihydro-4H-thieno[2,3-c]pyrrole-3-carboxylate (cas# 1428234-04-1) is a useful research chemical.<br></p>

<p>Applications 2-[3-(chloromethyl)phenyl]pyrimidine (cas# 898289-51-5) is a useful research chemical.<br></p>

<p>Applications 4-Amino-2,6-dichloro-3-nitropyridine (cas# 2897-43-0) is a compound useful in organic synthesis.<br>References Palmer, A., et al.: Bioorg. Med. Chem., 16, 1511 (2008),<br></p>

<p>Applications tert-Butyl-7-[4-(4-fluorophenyl)-6-isopropyl-2-mesylaminopyrimidin-5-yl]-(3R,5S)-isopropylidine-(E)-6-heptenoate (cas# 371775-73-4) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications Contains approximately 12% dichloromethane and 8% ethyl acetate<br></p>

<p>Applications 2,5-Di-4-pyridinylpyrazine is a compound used in the preparation of isonicotonic acid derivatives used in the chemotherapy of tuberculosis.<br>References Cymerman-Craig, J., et al.: J Chem Soc., 4315-20 (1955);<br></p>

<p>Applications Oxazolidine-4-carboxylic acid hydrochloride (cas# 162285-30-5) is a useful research chemical.<br></p>

<p>Applications 5-(2-Pyridyl)isoxazole-3-carboxylic Acid is a useful reagent for the preparation of isoxazoles for treatment of neurological disease.<br>References Wrona, I., et al.: PCT Int. Appl. (2019), WO 2019209962 A1<br></p>

<p>Applications 3-Hydroxypiperidine is used as a reagent to synthesize trisubstituted ureas, compounds that act as thrombin receptor (PAR-1) antagonists. 3-Hydroxypiperidine is also a metabolite of Piperidine (P479985), Piperidine is an organic heterocyclic amine widely used as building block and reagent in the synthesis of organic compounds including pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barrow, J., et al.: Bioorg. Med. Chem. Lett., 11, 2691 (2001); Reshmi, S.K., et al.: J. Med. Plant. Res., 4, 1535 (2010); Wiles, J.A., et al.: J. Med. Chem., 54, 3418 (2011);<br></p>

<p>Applications 4-BROMO-2-PYRIDINECARBOXAMIDE (cas# 62150-46-3) is a useful research chemical.<br></p>

<p>Applications 2,4-Diamino-6-hydroxypyrimidine-15N3 (cas# 1638736-04-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Hydroxy-3H-imidazole-4-carboxamide (cas# 56973-26-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-(Difluoromethyl)-1h-pyrazol-3-amine<br></p>

<p>Applications N-(Benzoyl)piperazine-2,2,3,3,5,5,6,6-d8 (CAS# 1219805-49-8) is a useful isotopically labeled research compound.<br></p>

<p>Stability N/A<br>Applications (R)-(-)-4-Phenyl-2-oxazolidinone (cas# 90319-52-1) is a compound useful in organic synthesis.<br></p>