Heterocycles with Nitrogen (N)

Impurity Irbesartan Bromo N2-Trityl Impurity
Stability Moisture Sensitive
Applications An intermediate in the synthesis of Losartan and Valsartan.

Applications An intermediate in the preparation of Pipradrol Hydrochloride

Applications 1-Isopropyl-d7-piperazine (CAS# 2089679-76-3) is a useful isotopically labeled research compound.

Applications 1-(4-Hydroxyphenyl)piperidin-2-one (cas# 79557-03-2) is a compound useful in organic synthesis.

Applications 2-Chloro-6-ethyl-N,N-dimethylthieno[2,3-d]pyrimidin-4-amine-d6 is the isotope labelled analog of 2-Chloro-6-ethyl-N,N-dimethylthieno[2,3-d]pyrimidin-4-amine (C367635); a useful synthetic intermediate.

Applications Pyrrolidine-2,2,5,5-d4 Hydrochloride is the salt, labeled analogue of Pyrrolidine (P997950), a heterocyclic compound used as a building block in the synthesis of wide range of pharmaceutical compounds, namely matrix metalloprotein inhibitors (MMPIs) and aminopeptidase N inhibitors (APNIs).
References Li, X. et al.: Mini-Rev. Med. Chem., 10, 794 (2010); Gragutan, I. et al.: Beil. J. Org. Chem., 7, 699 (2011)

Applications 2-Chloro-4-piperidinopyrimidine

Applications (7H-Pyrazolo[3,4-b]pyridin-5-yl)methanamine Hydrochloride is a useful research chemical.

Applications 2-(1-Piperidino)aniline is used to prepare oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. It is also used to synthesize benzimidazole derivatives as AMP-activated protein kinase activators.
References Liu, G., et al.: J. Med. Chem., 46, 2093 (2003); Charton, J., et al.: Bioorg. Med. Chem., 14, 4490 (2006)

Applications 5-Chloro-2,3-difluoropyridine is a 2,3,5-trihalopyridine used in the preparation of the herbicides and pesticides such as chodinafop-propargyl.
References Chen, Q. et al.: Jin. Huag. Zhong., 35, 35 (2005); Feng, C. et al.: Nonyao, 46, 793 (2007);