Building Blocks

<p>3-Hydroxy-2-nitrobenzonitrile (3HNB) is a biomolecule that has been systematically studied. It is a cyclic molecule with two nitro groups, and is synthesized by the reaction of 3,4-dihydroxybenzonitrile with nitric acid. The crystal structure of 3HNB was determined by X-ray diffraction to be orthorhombic and space group Pbca. The kinetic and thermodynamic parameters of 3HNB have been investigated in tumour cell lines. Mechanistic studies show that it inhibits the proliferation of tumour cells by binding to DNA and inhibiting DNA synthesis. This inhibition leads to cell death via apoptosis or necrosis, depending on the concentration of 3HNB used.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(3-Methylbutyl)-2-(propan-2-yl)propane-1,3-diol is a phthalate that is used as a plasticizer. It has been shown to have catalytic activity for the polymerization of dibenzoate and benzoate. 2-(3-Methylbutyl)-2-(propan-2-yl)propane-1,3-diol is also used as a catalyst in the synthesis of polyesters. 2-(3-Methylbutyl)-2-(propan-2-yl)propane-1,3-diol can be synthesized from propylene and butanol by reacting them in the presence of an acid catalyst.</p>

<p>2-Cyano-2-cyclohexylideneethanethioamide is a synthetic compound with the chemical formula (CH3)2CS. It has a crystalline structure and hydrogenated bonds. The primary amines in this compound are piperidine and salicylaldehyde. 2-Cyano-2-cyclohexylideneethanethioamide reacts with amines to form reaction products, which can also be alkylated. This synthetic compound is active methylene, making it an important structural analysis tool. Diffraction patterns of this compound have been analyzed to determine its molecular structure.</p>

<p>2-Cyano-2-cyclopentylideneethanethioamide is a cycloaddition reaction product of 2-cyanoacetic acid and triethylamine. It is a structural analog of the amino acid lysine, with the sulfur atom replaced by a cyano group. The compound reacts with thiols or amines to form unsaturated amides. This reaction can be used in the synthesis of heterocycles such as pyridine and quinoline.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Methyl-1H-indazole-3-carboxamide belongs to the group of indazole derivatives. It is a potent inhibitor of HIV replication and is used as an antiretroviral drug. 1-Methyl-1H-indazole-3-carboxamide has been shown to have antiviral activity against different types of viruses, such as hepatitis B virus, herpes simplex virus type 1, and human cytomegalovirus. The mechanism of action for this drug is not fully understood; however, it may inhibit viral protein synthesis by acting at the level of the polymerase chain reaction. This drug also has a number of side effects on the mother and infant, including metabolic disorders in both, increased body mass index in infants, and increased maternal mortality rates for women with HIV infection.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Methyl-3,4-dihydroisoquinolin-1(2H)-one is a detectable compound that is found in adventitia. It has been shown to have polymerase activity and can be used to inhibit restenosis following angioplasty. 5-Methyl-3,4-dihydroisoquinolin-1(2H)-one inhibits the proliferation of vascular smooth muscle cells by inhibiting the synthesis of phosphoenolpyruvate, which is an important substrate for cellular respiration. This drug also inhibits cellular proliferation and neointimal hyperplasia in a hepatoma cell line. The drug has been shown to be effective at reducing neointimal hyperplasia following angioplasty in a porcine model of vascular injury.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Pent-4-yn-1-yl)cyclohexane-1,3-dione is a molecule that has been shown to inhibit the growth of pancreatic cancer cells in vitro. It also inhibits the proliferation of miapaca2 cells. The mechanism of 4-(Pent-4-yn-1-yl)cyclohexane-1,3-dione's anti-cancer activity is not yet known. This molecule may be a factor receptor antagonist or an inhibitor of epidermal growth factor (EGF). It binds to the epidermal growth factor receptor (EGFR), preventing ligands from binding and inhibiting cellular proliferation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

3-[1-Butyl-5-(diethylsulfamoyl)-1H-1,3-benzodiazol-2-yl]propanoic acid is a versatile compound with various applications. It is commonly used as a fatty acid in the synthesis of cannabinoids and carotenoids. This compound is also categorized under Research Chemicals, making it an essential tool for scientific studies and experiments.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-3-(4-fluorobenzenesulfonamido)benzoic acid (CAS No. 729561-80-2) is a custom synthesis chemical that has been modified to include fluorine, methylation, and click chemistry. It is a white solid with a melting point of 103°C. This compound is an oligosaccharide and polysaccharide that can be used in the synthesis of complex carbohydrates. This chemical is also useful for the modification of saccharides, sugars, and monosaccharides.</p>

<p>N-Cyclohexylidene-2-methylpropane-2-sulfinamide is a protease inhibitor that has been shown to inhibit the activity of proteases such as HIV and hepatitis C virus. It is coadministered with ribavirin, an antiviral agent, and interferons for the treatment of these diseases. This drug also can be used in combination with other drugs for the treatment of cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

3,5-dimethoxyphenyl isothiocyanate (3,5-DMPIC) is a benzimidazole derivative that has been shown to be a potent and selective antagonist of the gonadotropin-releasing hormone (GnRH). 3,5-DMPIC has been shown to desensitize GnRH receptors on the pituitary gland and may have applications in the treatment of prostate cancer. It also inhibits the release of luteinizing hormone and follicle stimulating hormone from the pituitary gland.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Acetamides are a class of organic compounds that are used as solvents and pharmaceuticals. They have been shown to have diastolic pressure-lowering effects, with the mechanism of action being inhibition of the enzyme activity that produces prostaglandin E2. Acetamides also have chemoattractant properties, which may be due to their ability to inhibit the production of chemokines. Acetamides are also known to exhibit antiinflammatory activity and can be used in experimental models for neurodegenerative diseases such as Alzheimer's disease. Acetamides can also lower collagen synthesis in fat cells, which may be useful for the treatment of obesity. Acetamides have been shown to bind to glucocorticoid receptors and regulate gene expression by affecting transcriptional factors such as NF-κB.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>