Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Bromo-7-methoxy-2H-1-benzopyran-2-one is a coumarin derivative that has been shown to cause liver lesions in rats. The compound can also inhibit locomotor activity, as well as have a significant effect on the levels of serum prolactin. 3-Bromo-7-methoxy-2H-1-benzopyran-2-one is a ligand for the 5HT2 receptor, and it has been suggested that this may be due to its coordination geometry. In addition, 3BMOP binds to DNA with high affinity and specificity, which suggests that it could be used as an antitumor agent.

Versatile small molecule scaffold

Versatile small molecule scaffold

PB-22 is a synthetic cannabinoid, which can be classified as a CB1 receptor agonist. It is one of the many cannabinoids that have been created in an attempt to circumvent drug laws by creating compounds that are similar to those found in cannabis but have different chemical structures. PB-22 has shown to increase locomotor activity and stimulate the cb1 receptor in mice. Magnetic resonance spectroscopy (MRS) and assays were used to determine the binding affinity of PB-22 for the CB1 receptor. The MRS data showed that PB-22 bound with high affinity to the CB1 receptor and had a lower affinity for CB2 receptors. This suggests that PB-22 may be more potent than other synthetic cannabinoids, such as JWH-018 and CP 55,940, which bind better with CB2 receptors than CB1 receptors.
PB-22 is an analog of JWH-073 and has been shown to have a stronger effect on locomotor activity than JWH

2-Bromo-1,3,5-triisopropylbenzene is an ethylene acetal that is prepared by the catalyzed reaction of aryl chlorides and anhydrous zinc bromide in the presence of triethylamine. The selectivities of this method are high because it can produce mainly a single isomer. The stereoselectivity is also high because the reaction proceeds with the formation of only one stereoisomer. The mechanism for this reaction involves a nucleophilic substitution of the halogenated aryl chloride with the trialkylborane, which generates two different products. This product has been used in the synthesis of biphenyls and nitro compounds.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-(2-Hydroxyethyl)-2,6-dimethoxyphenol is a phenolic compound that can be extracted from the bark of the Indian tree Terminalia arjuna. The extract has been used in traditional medicine for centuries to treat diabetes and cancer. In vitro studies have shown that this extract inhibits the activity of viruses, including HIV, with a mechanism of action similar to that of indinavir. 4-(2-Hydroxyethyl)-2,6-dimethoxyphenol also has an antioxidant effect and stimulates the production of glutathione reductase and superoxide dismutase by cells in culture. 4-(2-Hydroxyethyl)-2,6-dimethoxyphenol is used as an herbal drug in India and research has found it to be hepatoprotective when administered orally to rats.

Versatile small molecule scaffold

Versatile small molecule scaffold

Ethyl 5-oxoheptanoate is a clear, colorless liquid that can be synthesized by reacting benzene with acetone. The synthesis of ethyl 5-oxoheptanoate is an example of a Friedel-Crafts reaction. This chemical is soluble in organic solvents such as acetone and cyclohexane and has low toxicity. It can be used as a reagent for the preparation of esters from alcohols, phenols, or carboxylic acids. Ethyl 5-oxoheptanoate can also be used to prepare resorcinol, which is a precursor to polymers and dyes, by hydrogenation of the molecule. Preparative methods are often used to produce this product because it has limited solubility in water.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-[1-(Difluoromethyl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid is a potent inhibitor of peptide binding to the receptor. It has a Kd value of 0.2 μM and a Ki value of 1.6 μM in the inhibition of insulin binding to its receptor. 2-[1-(Difluoromethyl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid is also an activator of protein interactions and ligand for research tools used for studying ion channels and other receptors. This chemical can be used as high purity reagent for life sciences, including cell biology and pharmacology.

Versatile small molecule scaffold

Versatile small molecule scaffold

3-(Methylsulfonyl)benzyl alcohol is a ketone that inhibits the catalytic hydrogenation of benzyl groups. It also has been shown to be an antagonist of β-adrenergic receptors. 3-(Methylsulfonyl)benzyl alcohol is used as a catalyst in catalytic bromination and has also been shown to have anti-inflammatory properties.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Vinyltributyltin is a dibutyltin oxide (DBTO) enantiomer that has been shown to inhibit the HIV-1 protease. Vinyltributyltin has also been shown to reduce inflammation in bowel disease, as well as to have synergistic effects with other drugs in the treatment of cancer and inflammatory bowel disease. The mechanism of action of vinyltributyltin is not yet known, but it may be related to its ability to inhibit the quinazolone-dependent formation of reactive oxygen species. Vinyltributyltin also inhibits the NS3 protease, which is an enzyme involved in hepatitis C virus replication.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Cyanobenzaldehyde is an aldehyde that reacts with nucleophiles such as trifluoromethanesulfonic acid to form a molecule. 2-Cyanobenzaldehyde has potent inhibitory activity against the kinase glycogen synthase kinase 3 (GSK3) and can be used to treat autoimmune diseases. It also reacts with hydrochloric acid in solution to form an intermediate, which is then reacted with glycine and ATP to produce a chiral compound. The product of this reaction has been shown to be active methylene, which was synthesized by asymmetric synthesis.

Versatile small molecule scaffold

1-Hydroxycyclopentane-1-carbonitrile is a monomer that is hydrolyzed to form benzoin and cyanohydrins. It can be used in the production of scifinder as a monomer or dimerizer.

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.