Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Allylcyclohexanone is an unsaturated ketone that is synthesized by the ring-opening of allyl cyclohexane carboxylate with sodium hydroxide. It can be used as a chemical intermediate for the synthesis of other compounds. 2-Allylcyclohexanone can also be used to react with hydroxide solution to produce a salt and an alcohol. The hydroxide solution can act as a base, reducing the carbonyl group in the presence of an acid to form the corresponding alcohol. This reaction is stereoselective because it only occurs when there are two different groups on adjacent carbons.
2-Allylcyclohexanone has been shown to inhibit non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as nevirapine, efavirenz, and delavirdine. In addition, it has been found to have functional groups that are capable of reacting

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Phenyl-1,3,4-oxadiazole is a 2-phenyloxazole with an oxygen atom at the 1 position. It is a white crystalline solid that is soluble in water and has antibacterial properties. This chemical can be used as a catalyst for the synthesis of organic compounds. 2-Phenyl-1,3,4-oxadiazole reacts with nitro groups to form oxime derivatives and has been shown to inhibit the growth of fungi such as Candida albicans and Aspergillus niger. 2-Phenyl-1,3,4-oxadiazole can also be used as an antifungal agent against Trichophyton rubrum.
2-Phenyl-1,3,4-oxadiazole may be synthesized by reacting phenol with acetone in the presence of nitric acid or sulfuric acid. The structural formula for this compound is

The Opn4 antagonist is a chemical that blocks the activity of the protein melanopsin, which is involved in regulating circadian rhythms. It has been shown to inhibit melatonin synthesis and muscle fiber contraction when applied intravitreally. These effects may be mediated by membrane channels that are activated by chloride ions. The effect of the Opn4 antagonist on photoreceptor cells is not yet known.

Please enquire for more information about 4-Bromomethyl-4'-methyl-2,2'-bipyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

4-Fluorobenzoyl isothiocyanate (FBITC) is a fluorescent molecule that binds to the glutamate receptor. The binding of FBITC to the GluN2B subunit of the NMDA receptor leads to conformational changes in the receptor and decreases its ability to bind glutamate. This process has been shown using x-ray diffraction data, which also showed that FBITC was able to chelate with magnesium ions, indicating a possible allosteric modulator for these receptors.

Versatile small molecule scaffold

Methyl 2-octynoate is a chemical that has been shown to bind to the nicotinic acetylcholine receptor. Methyl 2-octynoate has been shown to have antitumor activity in various types of cancer cells, including breast, prostate, and lung cancer cells. This chemical is not known to be chemically stable or film-forming. It also disrupts mitochondrial membrane potential and reduces the endpoints of oxidative phosphorylation. Methyl 2-octynoate was found to have low potency against cancer cells in vitro and in vivo.

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Iodo-2-methyl-1-nitrobenzene is a prodrug that is converted to its active form, 4-iodo-2-methylbenzenesulfonamide, by hydrolysis. It has been shown to regulate the expression of genes that are involved in the regulation of cellular proliferation and cell cycle progression. The FTIR spectrum of 4-iodo-2-methylbenzenesulfonamide shows a redshift from 1730 cm−1 to 1680 cm−1, which is indicative of the photorelease of nitrosamines. This drug has been used for the treatment of cancer, in particular for chlorambucil resistant cancers. The functional groups on this compound have been shown to be efficient for chemistry with other compounds and biomolecules.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Iododibenzofuran is a fluorescent compound that has been used as a probe for the study of neutral endopeptidase activity. The compound is characterized by a high degree of thermal stability and an inhibitory potency at pH 7.0 that is approximately 3 orders of magnitude greater than that of the active site inhibitor, anthracene. 3-Iododibenzofuran can be synthesized using chemoenzymatic methods, with efficiencies and profiles that are similar to those obtained in the conventional method. This probe can also be used to investigate the functional role of proteins in living cells or tissues.
3-Iodobenzofuran has been shown to have pressor effects in rats and can cause tetrazole (a type of explosive) to detonate when heated, which makes it unsuitable for use in devices such as explosives or pyrotechnics.

Versatile small molecule scaffold

5-Fluoro-2-nitrobenzoyl chloride is a conformationally locked macrocyclic compound that has been synthesized by solid phase synthesis. It is found in two conformational states and can be made to switch between these two states by applying a force to the molecule. This conformation can be controlled by changing the side chain of 5-fluoro-2-nitrobenzoyl chloride, which can be done experimentally. The conformational behavior of this macrocycle was studied using molecular dynamics simulations and it was found that there are four possible conformations for the molecule. The conformations with different side chains were found to have different energies, which could be used as a measure of their relative stability.

2,4-Dibromo-6-nitroaniline is a nitro compound that has been used in the production of dyes. It is also used as a component in the synthesis of other organic compounds. 2,4-Dibromo-6-nitroaniline can be produced by electrolysis of an acid solution containing radical cations and benzene. The radical cations are formed by proton transfer from the acid to the benzene, followed by electron transfer from benzene to the electrode. This process results in the formation of nitro groups on the benzene ring, which undergoes oxidation to form 2,4-dibromo-6-nitroaniline. The cyclic voltammetry shows that this process occurs via two pathways: one with a fast rate and one with a slow rate. The mechanism for this reaction is not yet known.

Versatile small molecule scaffold

Versatile small molecule scaffold

Tetrahydroquinolin-2(1H)-one is a hydrobromide that has been found in the environment as an environmental pollutant. Tetrahydroquinolin-2(1H)-one is used to synthesize amides and has been studied by single-crystal x-ray diffraction. The molecule is centrosymmetric, with a molecular weight of 244.06 g/mol. Tetrahydroquinolin-2(1H)-one can be used as a ligand for metals such as chlorine and magnesium. It does not dissolve in water but does dissolve in organic solvents such as ethers, chloroform, or benzene.

Versatile small molecule scaffold

Tris(hydroxymethyl)propane is a diphenyl ether that has been shown to have an electrochemical impedance spectroscopy (EIS) spectrum in the human serum that is similar to those of other known antioxidants. Tris(hydroxymethyl)propane has been shown to protect against light-induced damage in human skin cells, and it also has radiation protective effects. Tris(hydroxymethyl)propane has also been shown to interact with trimethylolpropane, which is another antioxidant, and this interaction may affect the effectiveness of each agent. Tris(hydroxymethyl)propane inhibits lipid peroxidation by inhibiting the oxidation of fatty acids and hydroxyl groups on proteins.

(3,3,3-Trifluoroprop-1-yn-1-yl)benzene is a reaction product that can be used to inhibit the activity of metalloprotease and as an anti-cancer agent. This compound inhibits the enzyme that causes chronic kidney disease and degenerative diseases. It is a potent inhibitor of metalloprotease, which is involved in cancer progression, fatty acid synthesis and bone formation. The effective dose for this drug is between 1 and 10mg/kg body weight. It has been shown to have an asymmetric synthesis with the use of amido groups. (3,3,3-Trifluoroprop-1-yn-1-yl)benzene also has antirheumatic properties due to its ability to inhibit proteases such as matrix metalloproteinases and cathepsins.

Pregabalin Impurity 13 is a stereoselective, synthetic compound that has been shown to be an inhibitor of gamma-aminobutyric acid (GABA) receptors. It can be synthesized by reacting 4-isobutyl-2,6-piperidinedione with hydrochloric acid and xylene. Pregabalin Impurity 13 binds to the amino acid sequence of GABA receptors in such a way as to prevent them from opening. This prevents the binding of GABA molecules to the receptor and reduces the duration of inhibition of these receptors. Pregabalin Impurity 13 has been shown to have antimicrobial activity against faecalis, which is found in human intestines and can cause infection. The environmental pollution caused by this impurity is due to its xylene content.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Ethyl 2-(propan-2-yloxy)acetate is a high concentration organometallic compound that is an active substance. The organometallic compound consists of a magnesium atom, an aliphatic hydrocarbon group, and a polyolefin. It has been shown to have a blood pressure lowering effect in rats. Ethyl 2-(propan-2-yloxy)acetate is an ester compound that acts as an intermediate in the production of other substances with therapeutic properties.

4-[(Methylsulfanyl)methyl]benzoic acid is a chiral compound with a sulfur atom. It can be prepared by the reaction between methylsulfonyl chloride and benzoyl chloride in chloroform or by the reaction of methoxysulfur trifluoride with benzoic acid. 4-[(Methylsulfanyl)methyl]benzoic acid can also be synthesized by the reaction of sulfone and carboxylic acid derivatives, such as benzyl or cyano. 4-[(Methylsulfanyl)methyl]benzoic acid is used as a fungicide, insecticide, and herbicide. The substituents on this molecule are able to form bonds with other molecules to create an array of different structures. The most common substitution is for methoxy, which has a hydroxy group attached to it. This substitution is found in many different types of molecules including some drugs, hormones, vitamins,

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3,4-Dihydro-2H-1-benzopyran-7-ol is a monomer that is used to synthesize medicines. It has the formula CH3COCH=CH(OH)CH3 and belongs to the group of flavonoids. 3,4-Dihydro-2H-1-benzopyran-7-ol has acidic properties, which are due to its isoflavones. It can be used as an acid catalyst in organic synthesis reactions and is a reaction product of chloropropane. 3,4-Dihydro-2H-1-benzopyran-7-ol also has high yield and can act as a bioisostere for other compounds such as chromene.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,2-Dibromopropane is a synthetic chemical that has been used as a precursor in the production of nylon. It is an activator that can be used to form covalent bonds with reactive groups on other molecules. The activation energy for the reaction with piperazine is between 104 and 106 kJ/mol. 2,2-Dibromopropane undergoes acylation reactions under certain conditions, forming reaction products such as 2,2-dibromoethyl acetate and 2,2-dibromoethanol. The molecular weight of 2,2-dibromopropane is 192.19 g/mol and its structural formula is CHBrCHBrCHBrCHBrC≡C≡C≡C≡C≡C≡CC(O)OH.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

1-Hydroxycyclopentane-1-carbonitrile is a monomer that is hydrolyzed to form benzoin and cyanohydrins. It can be used in the production of scifinder as a monomer or dimerizer.

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.