Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

(2-Methylprop-2-en-1-yl)thiourea is a lead compound that has been shown to have acetylcholinesterase and butyrylcholinesterase inhibitory activity. It has been shown to have antioxidant properties and may be used as an antiinflammatory agent. This drug has also been shown to have neuroprotective effects in animals with Alzheimer's disease by inhibiting the progression of the disease. The biological activity of (2-Methylprop-2-en-1-yl)thiourea is not limited to mammals, as it has also been shown to protect against oxidative damage in cells from pigs, horses, and chickens.

Methyl(2-phenylpropan-2-yl)amine is a synthetic compound that inhibits the replication of chronic kidney disease (CKD) related viruses. It is metabolized to malonic acid and benzylamine derivatives, both of which are plasma biomarkers for CKD progression. Methyl(2-phenylpropan-2-yl)amine has been shown to have anti-depressive effects in animal models, as well as inhibitory effects on inflammatory diseases and circulatory system disorders.

6-Chloro-5-methylpyridine-3-carboxylic acid (6CMP) is a pyridine that is used for the treatment of lymphoma. 6CMP binds to the brain tissue and has been shown to have affinity for thiophene receptors. It can be found in blood and has an oral profile. 6CMP also has a medicinal chemistry profile, which includes inhibition of protein synthesis, DNA replication, and RNA transcription. This compound can be used as a medicinal drug with its chemical properties as an antitumor agent and immunosuppressant.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3,4-Dimethoxy-5-nitrobenzoic acid is a compound that can be used in the synthesis of pharmaceuticals. It has been shown to inhibit methylene amide demethylation and may have potential as an inhibitor of the enzyme catechol-o-methyltransferase. 3,4-Dimethoxy-5-nitrobenzoic acid is also used as a synthetic intermediate in the preparation process for other compounds. This chemical is bifunctional, with one functional group being electron rich and the other electron poor. The two functional groups are connected by a spacer molecule. Potassium is often used to prepare this chemical from its corresponding potassium salt.

Versatile small molecule scaffold