Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>The Glutaminase Inhibitor II, BPTES is a glutaminase inhibitor that is used to treat cancer. It binds to the active site of glutaminase and inhibits the enzyme from catalyzing the conversion of glutamine to glutamate. This results in reduced production of ATP, which leads to cell death. The minimal toxicity of this drug has been shown in animal models using a dinucleotide phosphate-based assay. BPTES has also been shown to inhibit mitochondrial membrane potential and induce apoptosis by decreasing levels of reactive oxygen species (ROS) and increasing mitochondrial membrane potential in a model system. BPTES can also synergize with other drugs such as anticancer agents or radiation therapy, resulting in increased efficacy against tumor cells.</p>

<p>C-176 is a human monoclonal antibody that binds to the death protein and neutralizes its activity. It also inhibits angiogenesis by inhibiting the proliferation of endothelial cells. C-176 has been shown to reduce blood pressure in animal models. The mechanism for this effect is not known, but it may be due to its ability to inhibit the production of proinflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which are stimulators of endothelial cell proliferation. C-176 also has regulatory effects on T cells, B cells, natural killer cells, and macrophages. It inhibits the coagulation process by reducing platelet aggregation and thrombin formation. This drug is an inhibitor of single-stranded DNA binding proteins and can be used in radiation therapy or as a stimulator of bone marrow stem cells in patients undergoing chemotherapy.<br>END&gt;&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-fluoro-4-(methoxycarbonyl)benzoic acid is a hydrogen bond acceptor that can form hydrogen bonds with other molecules. It is also a weak donor of protons. 2-fluoro-4-(methoxycarbonyl)benzoic acid can form dimers and interacts with benzene, as well as carboxylate groups in the same molecule. The carboxyl group of this molecule can be deprotonated to form the corresponding carboxylate anion. 2-fluoro-4-(methoxycarbonyl)benzoic acid has two dihedral angles, which are coplanar, and a benzene ring.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 1-(6-chloro-3-pyridazinyl)-4-piperidinecarboxylate is an antibacterial agent that inhibits the growth of bacteria by inhibiting the synthesis of proteins needed for cell wall biosynthesis. It has been shown to be more potent than other quaternary ammonium compounds, such as tetrachloropyridazine and tetrachloropyrimidine. Methyl 1-(6-chloro-3-pyridazinyl)-4-piperidinecarboxylate is used in coatings for use in agriculture, as well as in industrial processes that involve ethylene glycol or ether. This compound is also used in the production of neodymium and ethanol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Hydrazinylpyridine-4-carboxylic acid is a chemical compound that is a demethylase inhibitor. It has been shown to penetrate the blood brain barrier and inhibit histone lysine demethylases, which are enzymes responsible for altering the methylation state of histones. 3-Hydrazinylpyridine-4-carboxylic acid has been studied extensively in biochemical assays and cellular models, but its mechanistic activity remains unclear. The medicinal chemistry optimization of this compound may provide insight into other potential therapeutic applications.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>KIRA6 is a neurotrophic factor that functions as a chemoattractant for neuronal cells and regulates neuronal cell growth. It also has been shown to be a potent inhibitor of serine protease, which is important in the inflammatory response pathway. KIRA6 is used in cancer research to study the response pathway of cancer cells to chemical inhibitors. The KIRA6 protein has homology to other neurotrophic factors, such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). KIRA6 also has been shown to inhibit the influenza virus and reduce inflammation in mice with inflammatory diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>7-Bromo-1H-benzo[d][1,2,3]triazole is an organic solvent with a molecular weight of 126.12 g/mol and a boiling point of 266 °C. It has a basic group and a hydroxyl group. The nitrogen atoms are present in the molecule as well as two silver ions that have been shown to be important for viral life and cancer treatment. 7-Bromo-1H-benzo[d][1,2,3]triazole also has two monocarboxylic acid groups and one polycarboxylic acid group. It is used as corrosion inhibitor, which may be due to its ability to inhibit glutamate activity and metal ion complexation. This compound also contains a residue that can be hydrolyzed by enzymes found in human proteins.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2,3-Dibromophenyl)methanol is a synthetic compound that has been shown to have antimicrobial activity. This compound inhibits phosphatase activity and also has an effect on the ecosystem by inhibiting the growth of bacteria that produce dopamine. It is also used as a reagent in techniques such as bromophenol blue assays and glucose 6-phosphate dehydrogenase assays. The antibacterial properties of this compound may be due to its ability to bind to the cytoplasmic membrane through bromophenols or other unknown mechanisms.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>