Building Blocks

<p>Methyl 2-bromo-6-(bromomethyl)benzoate is a pharmacological agent that belongs to the group of dopamine D2-like receptor ligands. It has been shown to bind to the dopamine D2-like receptor in rat brain tissue, and has affinity for this receptor. Methyl 2-bromo-6-(bromomethyl)benzoate may induce behavioral effects by interacting with the dopamine system in the central nervous system. This compound binds to dopamine receptors, especially those with affinity for D2-like subtypes. The binding of this compound induces conformational changes in the receptor, which leads to changes in downstream signal transduction and ultimately influences behavior.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-({5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl}sulfanyl)benzoic acid is a synthetic nonpeptide compound that belongs to the group of ligands. This inhibitor binds to nicotinic acetylcholine receptors and inhibits their activity. 2-({5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl}sulfanyl)benzoic acid has been shown to be a potent activator of these receptors. This compound also inhibits voltage dependent potassium channels and calcium channels.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde is a reactant that can be used in the synthesis of salicylaldehyde and phenyl isocyanate. It reacts with a variety of reagents, including salicylic acid, phenyl isocyanate, and isocyanates to produce high yields. This product also reacts with transaminases to produce pyrazole derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromocyclopent-2-en-1-one is an organic compound that belongs to the group of cycloalkenones. It is a methyl ester with a cyclopentane backbone and a ketone group at the end of the molecule. 3-Bromocyclopent-2-en-1-one is synthesized by a cross-coupling reaction between zinc chloride and 3,4,5,6,7,8,9,10,11 bromodecane. The product can be isolated in crystalline form as well as in yields up to 90%. The product has been shown to act as an analog for prostaglandin E2.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methyl-4-oxo-4-phenylbutanenitrile is a chemical compound that is used in the synthesis of pharmaceuticals. It can be obtained by reacting an organic base with an organic acid. This reaction takes place in a reaction vessel and requires an inorganic base and inorganic reagents. The process also requires ethyl cyanoacetate as the starting material and produces 2-methyl-4-oxo-4-phenylbutanenitrile as the product. The use of this chemical has been linked to environmental pollution, so it should never be released into the environment or come into contact with water.</p>

<p>Versatile small molecule scaffold</p>

<p>(2R)-3-[(Carboxymethyl)sulfanyl]-2-acetamidopropanoic acid is a metabolite of the drug sulfapyridine. It is formed by conjugation with glutathione in the liver to form 3-glutathione-2-sulfapyridine, and then excreted into bile. (2R)-3-[(Carboxymethyl)sulfanyl]-2-acetamidopropanoic acid has been found to be genotoxic in mice, which may be due to its ability to form reactive metabolites that bind to DNA. This compound also possesses cytotoxic properties, which may be due to its ability to inhibit protein synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Methyl-4-phenoxyaniline is a molecule that inhibits chitinase, an enzyme that catalyzes the hydrolysis of chitin, and molting. N-Methyl-4-phenoxyaniline has been shown to be potent inhibitor of the enzyme amide in vitro. It also inhibits onchocerca volvulus and in vivo, which may be due to its ability to inhibit the synthesis of fatty acids. This drug has not been tested against other parasites or mammals, but it is an anthelmintic drug.</p>

<p>1-(3-Chlorophenyl)-1H-pyrazole-4-carbaldehyde is a pesticide that acts as a selective insecticide. It is effective against the larval stage of insects, such as the cabbage moth, Plutella xylostella. This compound has been shown to have biological activity against mites and insects with hydrazine hydrochloride and cinnabarinus. 1-(3-Chlorophenyl)-1H-pyrazole-4-carbaldehyde has also been shown to be able to cyclize with hydrazine to form an insecticidal compound.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-(Prop-2-yn-1-yl)-1,3-thiazol-2-amine (P2Y) is a nonselective antagonist for the P2Y receptors. It has been shown to inhibit hyperplasia in the rat prostate and to reduce gland size in rabbits with induced hyperplasia. It also has been shown to be effective in preventing cancer development in an animal model. This drug is used as a pharmaceutical formulation to treat prostate conditions such as benign prostatic hyperplasia and prostatitis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Ethylphenyl)-2-methylpropanoic acid is a Grignard reagent that can be used in the synthesis of alectinib. It is obtained by reacting acetophenone with n-iodosuccinimide, followed by the addition of an ethyl magnesium bromide solution. This reagent reacts with aryl halides to form Grignard compounds. 2-(4-Ethylphenyl)-2-methylpropanoic acid has been used to synthesize alectinib hydrochloride, which is an anti-cancer drug, and also as a high yield industrial chemical reagent.</p>

<p>2-Amino-4-methyl-pyrimidine-5-carboxylic acid is a spleen cell immunogen that induces antibody production in animals. 2-Amino-4-methyl-pyrimidine-5-carboxylic acid is an immunogen that belongs to the class of pyrimidine carboxylic acids. It has been optimised for use as an animal vaccine by inoculating it into tissues and monitoring antibody production with an enzyme linked immunosorbent assay. This compound has also been used to monitor and screen for antibodies in liquid chromatography.</p>

<p>Versatile small molecule scaffold</p>

<p>Ethylhexanoic acid zinc salt is a viscosity-increasing agent that is used in the production of high-viscosity polymers. It is a carboxylate salt of ethyl hexanoic acid and zinc. The reaction of ethylhexane with zirconium oxide produces a viscous liquid with a strong cationic polymerization activity. This product reacts with diphenyl ether and aromatic hydrocarbons to form solid products. The reaction with calcium stearate, an ester of glycerol, results in the formation of particles that are insoluble in water but soluble in organic solvents. Ethylhexane also reacts with ethylene diamine to form methyl myristate, which has kinetic data available for it.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.</p>