Building Blocks

Stability Light Sensitive
Applications Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),

Applications An metabolite of Cotinine. In equilibrium with 5’-Hydroxycotinine the cyclized form.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Morselli, P.L, et al.: J. Med. Chem., 10, 1033 (1967); Murphy, S.E. et. al.: Chem. Res. Toxicol. 12, 639 (1999)

Applications Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease.
References Wenzel, A., et al.: J. Neurosci., 21, 53 (2001), Martinez., et al.: Development, 6, 851 (2002), Nakayama, K., et al.: J. Biochem., 146, 757 (2009), Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2009),

Stability Air Sensitive, Hygroscopic
Applications Methyl 9-Oxononanoate is a linseed oil-based coating. It is solventless polymeric protective.
References Thomas, F., et al.: J. Coating. Technol., 51, 51 (1979); McManis, G., et al.: J. Paint Technol., 43, 53 (1971)

Impurity Chlorpheniramine EP Impurity B
Applications A metal-complexing agent; an effective iron chelating agent to help protect against UVB radiation. An impurity of Chlorpheniramine Maleate (C424300).
References Bissett, D. et al.: Photochem. Photobiol., 54, 215 (1991); Patel, M.H. et al.: J. Enzyme Inhib. Med. Chem., 26, 188 (2011);

Applications 3-Cyclohexenylcarboxylic Acid has been found to be an oxidizable, nongrowth substrate and induces the metabolism of cyclohexanecarboxylic acid and benzoic acid in a strain of Pseudomonas putida. 3-Cyclohexenylcarboxylic Acid has been used as food for cultures of Streptomyces sp.  KCTC 11604BP fkbO deletion mutant to make 32-dehydroxy-FK506, a FK506 analogue containing a non-natural starter unit.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blakley, E.R., Papish, B.: Can. J. Microbiol., 28, 1324 (1982); Ban, Y.H., et. al.: Mol. bioSystems, 9, 944 (2013)

Applications N-(Methylcarbamoyl) Sulfanilamide-N4-acetate is a metabolite of Asulam. Also performs a herbicial function.
References Guardigli, A., et al.: Analytical Methods for Pesticides and Plant Growth Regulators, 13, 197 (1984); Heijbroek, W. M. H., et al.: Xenobiotica, 14, 235 (1984); Heywood, B. J., et al.: J. Sci. Food and Agr,3 (1668

Applications Bis(2-hydroxypropyl) Ether is commonly used as a plasticizer, an intermediate in industrial chemical reactions.
References Fasano, W.J., et al.: Toxicol. In. Vitro., 25, 1664 (2011); Ottavioli, J., et al.: Spectroscopy. Lett., 44, 221 (2011);

Applications An Intermediate in the synthesis of risperidone and iloperidone.

Applications methyl 1-(2,4-difluorophenyl)-3-phenyl-1H-pyrazole-5-carboxylate (cas# 1202030-37-2) is a useful research chemical.

Applications 2-Methylthiazolidine (cas# 24050-16-6) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Ketoglutaric Acid is a derivative of glutaric acid and is an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate.
References Son, J.Y., et al.: Nature., 496, 7443 (2013); Quartarao, C.E., et al.: Biochem., 52, 1765 (2013); Yum, S.H., et al.: Euro.J. Pharmacol., 699, 124 (2013);

Applications An α-keto ester derivative.

Applications N-(Phenyl)-2-naphthylamine is a reagent in the preparation of unsymmetrical triaryldiamines as thermally stable hole transport layers for various organic LEDs.
References Koene, B. et al.: Chem. Mat., 10, 2235 (1998)

Applications (±)-Warfarin Sodium, an anticoagulant drug product.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nguyenpho, A., et al.: J. Pharm. Sci., 104, 4232-4240, (2015)