Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Amino-4,4,4-trifluorobutan-1-ol is a chiral compound with an optical purity of &gt;99.5%. It is used in asymmetric synthesis as a reagent for the preparation of enantiopure compounds. 3-Amino-4,4,4-trifluorobutan-1-ol has a trifluoromethyl group which is not present in any other amino alcohols. This molecule can be synthesized by reacting 3,3'-dichlorodiphenyl sulfone with sodium azide and 1,3,3,-triethanolamine.</p>

<p>Versatile small molecule scaffold</p>

1-[2-(2-Methoxyethoxy)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione is a high molecular weight molecule with a diagnostic potential. It is synthesized through the substitution of hydrogen atoms on the pyrrole ring with methoxyethyl groups and has been shown to be a cation channel mediator. This compound is labeled with gold nanoparticles and used for in vitro and in vivo studies. In addition, this compound can be used as theragnostic agent for cancerous tumors.

<p>Versatile small molecule scaffold</p>

<p>2-Phenyl-5H-imidazo[4,5-c]pyridine (2-PI) is a pyridine derivative that has inotropic and vasodilator effects. It is used in pharmaceutical formulations for the treatment of heart failure and angina. 2-PI also acts as an anticoagulant by inhibiting the synthesis of prothrombin and fibrinogen. Furthermore, it increases the production of cAMP, which leads to increased levels of phosphodiesterase. The oxidizing properties of 2-PI have been shown to be helpful in treating bronchial asthma.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 1-(6-chloro-3-pyridazinyl)-4-piperidinecarboxylate is an antibacterial agent that inhibits the growth of bacteria by inhibiting the synthesis of proteins needed for cell wall biosynthesis. It has been shown to be more potent than other quaternary ammonium compounds, such as tetrachloropyridazine and tetrachloropyrimidine. Methyl 1-(6-chloro-3-pyridazinyl)-4-piperidinecarboxylate is used in coatings for use in agriculture, as well as in industrial processes that involve ethylene glycol or ether. This compound is also used in the production of neodymium and ethanol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Hydrazinylpyridine-4-carboxylic acid is a chemical compound that is a demethylase inhibitor. It has been shown to penetrate the blood brain barrier and inhibit histone lysine demethylases, which are enzymes responsible for altering the methylation state of histones. 3-Hydrazinylpyridine-4-carboxylic acid has been studied extensively in biochemical assays and cellular models, but its mechanistic activity remains unclear. The medicinal chemistry optimization of this compound may provide insight into other potential therapeutic applications.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>KIRA6 is a neurotrophic factor that functions as a chemoattractant for neuronal cells and regulates neuronal cell growth. It also has been shown to be a potent inhibitor of serine protease, which is important in the inflammatory response pathway. KIRA6 is used in cancer research to study the response pathway of cancer cells to chemical inhibitors. The KIRA6 protein has homology to other neurotrophic factors, such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). KIRA6 also has been shown to inhibit the influenza virus and reduce inflammation in mice with inflammatory diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2-Methylprop-2-en-1-yl)thiourea is a lead compound that has been shown to have acetylcholinesterase and butyrylcholinesterase inhibitory activity. It has been shown to have antioxidant properties and may be used as an antiinflammatory agent. This drug has also been shown to have neuroprotective effects in animals with Alzheimer's disease by inhibiting the progression of the disease. The biological activity of (2-Methylprop-2-en-1-yl)thiourea is not limited to mammals, as it has also been shown to protect against oxidative damage in cells from pigs, horses, and chickens.</p>

<p>[(Tetrahydrofuran-2-yl)methyl]thiourea is a thiourea that functions as an antimicrobial agent. It has been shown to be effective against fungal strains, including Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus. [(Tetrahydrofuran-2-yl)methyl]thiourea has also been shown to inhibit the growth of biofilms and human cell lines. The antimicrobial activity of thiourea can be attributed to its ability to form reactive oxygen species that cause oxidative stress in microbial cells. Thiourea disrupts the cell membrane and causes leakage of cellular contents such as proteins and nucleic acids. This disruption results in cell death by apoptosis or necrosis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl(2-phenylpropan-2-yl)amine is a synthetic compound that inhibits the replication of chronic kidney disease (CKD) related viruses. It is metabolized to malonic acid and benzylamine derivatives, both of which are plasma biomarkers for CKD progression. Methyl(2-phenylpropan-2-yl)amine has been shown to have anti-depressive effects in animal models, as well as inhibitory effects on inflammatory diseases and circulatory system disorders.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Chloro-5-methylpyridine-3-carboxylic acid (6CMP) is a pyridine that is used for the treatment of lymphoma. 6CMP binds to the brain tissue and has been shown to have affinity for thiophene receptors. It can be found in blood and has an oral profile. 6CMP also has a medicinal chemistry profile, which includes inhibition of protein synthesis, DNA replication, and RNA transcription. This compound can be used as a medicinal drug with its chemical properties as an antitumor agent and immunosuppressant.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>