Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Benzyl-N-methylacetamide is a cardiac stimulant and thermogenic that has been shown to increase the rate of metabolism in mammals. It is an electrophile that can be converted to a reactive form by perchlorates and other oxidizing agents. The resulting n-oxide reacts with amino acids, yielding iminium ions that react with amide bonds in proteins, altering their structure and function. N-Benzyl-N-methylacetamide has also been shown to have antioxidant properties in vivo studies on mice. It may also have carcinogenic effects due to its ability to induce oxidative stress and DNA damage.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Methyl 5-aminopentanoate hydrochloride is an amide that has a protonated methyl group. It is a colorless liquid with a boiling point of 173°C and a melting point of -7°C. The technique used to measure the affinity of this compound for benzyl esters is called titration. Methyl 5-aminopentanoate hydrochloride is also soluble in water, chloroform, and ether. The molecule has two methyl groups (CH3) and one carboxylic acid group (COOH). The physicochemical properties of this substance are determined by the size and charge of its atoms.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Dichloro-N-(2-methyl-3-oxobutan-2-yl)benzamide (3,5DCMB) is a herbicide that inhibits photosynthesis in plants. It is metabolized to dichlorobenzene and hydrated to 3,5-dichlorobenzaldehyde. The metabolites are excreted through the urine or via the lungs. 3,5DCMB is also a xenobiotic with an ethynyl group and a methyl ketone group.</p>

<p>Versatile small molecule scaffold</p>

<p>Octahydro-1H-inden-1-one is an alkylation agent that has been used in the synthesis of triketones and ethyl diazoacetate. This compound is a synthetic intermediate that is used to produce organic compounds. It can be prepared by the kinetic reaction of ethyl diazoacetate with chloride or by the thermolysis of 1,3,5-triketone. Octahydro-1H-inden-1-one can also be synthesized from octahydrobenzofuran using a regiospecifically catalyzed reaction. The compound exists as two regiospecific isomers due to its double bond: cis and trans. The cis form has greater reactivity than the trans form because it has two electron withdrawing groups on the same side of the double bond and it can be hydrolyzed more easily than its trans isomer.<br>Octahydro-1H-ind</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Bromo-3-methanesulfinylbenzene (1BrMS) is a chemoselective oxidant that can be used for the oxidation of sulfides and sulfoxides. 1BrMS has been shown to have an optimum pH of 9.5, and it has been shown to be catalytic in the presence of hydrogen peroxide. It also exhibits enantioselectivity and chemoselectivity as well as high regioselectivity. 1BrMS is stable under basic conditions, but breaks down under acidic conditions due to its reactive nature. The parameters of 1BrMS are not fully understood at this time, but it has been shown to be a powerful oxidant with potential applications in organic synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Propynyloxy)benzenecarbaldehyde (2-POBA) is a biomolecule that can be used as a fluorescence probe. It reacts with nucleophiles, such as pyridines and coumarins, to form radical species. 2-POBA has shown antibacterial activity against subtilis and other bacterial strains. The allyl group in 2-POBA is responsible for the antibacterial activity. 2-POBA also reacts with cyclic voltammetric and electrospray ionization techniques to produce an ion signal that is indicative of its presence in solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Azetidine-1-sulfonamide is a synthetic drug that can be used to treat autoimmune diseases. It is an inhibitor of the inflammatory chemokine and chloride secreted by macrophages, which prevents the activation of T cells. Azetidine-1-sulfonamide also has antibacterial activity against bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. The drug inhibits bacterial growth by binding to their DNA gyrase, preventing DNA synthesis and replication.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(1S)-1-(4-Iodophenyl)ethan-1-ol is an electrophilic reagent that is used in the synthesis of imidazoles. It is generated by the chemoenzymatic, regioselective alkylation of a phenyl ring with a stannylated phenyl amine. This process can be performed using a variety of different reagents and solvents, including N-chloro-N-methylpyridinium tetrafluoroborate (NCMP). The regioselectivity of the reaction ensures that the desired product is generated in high yield.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(2-Ethynylphenyl)ethan-1-one (1EPE) is a synthetic intermediate that is used in organic chemistry. It has two mechanisms, as an intramolecular diazonium salt or as a pyrylium ion. 1EPE can be synthesized from the reaction of ethyl acetoacetate with nitrobenzene and sodium hydroxide. It can also be produced by the displacement of 2,4-dinitrophenol with diethyl malonate, which produces diethyl malonic acid and 1EPE. The synthesis of 1EPE is important for the production of polycyclic aromatic compounds.</p>

<p>Mesotrione is a herbicide that belongs to the class of phenylpyrazole compounds. It is used for selective post-emergence weed control in corn, soybeans, and other crops. Mesotrione inhibits plant growth by inhibiting an enzyme called acetyl coenzyme A carboxylase, which is essential for fatty acid synthesis. This compound has been shown to be genotoxic in mammalian cells and plants when it binds with DNA and induces the formation of bulky adducts. The mechanism of mesotrione's genotoxicity has been studied using a model system involving E coli bacteria and monoclonal antibodies that are specific for the herbicide's metabolites. Chronic exposure to this compound may result in increased risk of cancer.</p>

<p>Versatile small molecule scaffold</p>