Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Amino-1-(thiophen-2-yl)propan-1-ol is a form of 3 amino propanol that has the chemical formula CH3CH2CH2N(CH3)S. It is an optical isomer of 1-(thiophen-2-yl)propan-1-ol and can be used as a pharmaceutical preparation in formulae with other drugs. 3 amino propanol can be prepared by reacting propionamide with ammonia, aralkyl amides, or amido groups. This reaction yields a mixture of the two optical isomers in a ratio of 1:5 to 5:1. The substance is also known as 6-alkyl, optically active, pharmaceutical preparations and formulae (6AOPPF).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Phenylpropanethioamide is an antibiotic that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to be a potent inhibitor of bacterial biosynthesis, which may be due to its ability to form reactive oxygen species and dimethyl disulfide. 3-Phenylpropanethioamide also binds to penicillin-binding proteins in the bacterial cell wall by competitive inhibition, preventing the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. 3-Phenylpropanethioamide is capable of forming radical intermediates from peroxide, which can lead to DNA damage and mutations.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(2,2-Dimethylpropyl)benzoic acid is a crystalline substance that can be found in polymers. It has a low energy and is soluble in hydrocarbons. 4-(2,2-Dimethylpropyl)benzoic acid is insoluble in solvents.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Methoxyphenyl)-piperazine is a piperazine derivative that binds to the serotonin transporter and blocks its function. It has been shown to have affinity for the serotonin transporter in radioligand binding assays, with an IC50 of 0.8 μM. 2-(2-Methoxyphenyl)-piperazine also acts as an antagonist at the 5-HT1A receptor, with an EC50 of 1.0 μM. This compound has optimal activity at a cycloalkyl group length of 4-6 carbon atoms and is a potent antagonist, with an IC50 of 0.3 μM.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylundecanoic acid is an acceptor of the nonribosomal peptide synthetase (NPS) enzyme. It is involved in the biosynthesis of branched-chain fatty acids and can be modified to produce other fatty acids. 3-Methylundecanoic acid is an intermediate in the synthesis of undecanoic acid, which is a major component of some bacterial cell membranes. 3-Methylundecanoic acid can also be used as a starting material for the production of synthetic, nonribosomal peptides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(4-Iodophenyl)-1H-pyrrole-2,5-dione (1IPD) is a molecule that belongs to the endocannabinoid class of molecules. 1IPD is a lipophilic compound that can be identified by fluorescent spectroscopy and has been found in fatty acid and cholesterol esters. 1IPD binds to the active site of the enzyme fatty acid amide hydrolase, which is responsible for the breakdown of anandamide and other related molecules. This binding inhibits the activity of the enzyme, leading to an increase in levels of anandamide and other related molecules in cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Tert-Butyl 6-bromohexanoate is an intermediate in the synthesis of a variety of organic compounds, including pharmaceuticals. It is also used as a reagent for various reactions and as a solvent in chemical syntheses. Tert-Butyl 6-bromohexanoate can be used to generate other chemicals through the following reactions: 1) Organic Synthesis 2) Addition of Grignard Reagents 3) Reduction of Ketones 4) Alkylation with Bromides 5) Dehydration with HBr 6) Conversion to Halides 7) Reduction of Esters 8) Oxidation with PCC or MCPBA 9) Conversion to Nitriles 10) The Williamson Reaction</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-5-hydroxybenzamide (2AB) is a hydroxylating agent that activates the microsomal enzyme cytochrome P450. This activation leads to an increase in the activity of various drug metabolizing enzymes, including those involved in the metabolism of drugs and xenobiotics. 2AB has been shown to denature proteins, such as anthranilamide and tyrosine, in rat liver homogenates. The activation of this hydroxylase may be due to the presence of copper ions or 2AB binding to tyrosine residues on proteins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Benzyl N-ethylcarbamate is a carbonyl compound that inhibits the activity of enzymes involved in the production of beta-amyloid peptide. This drug has been shown to be effective in the treatment of depression, inflammatory diseases, and autoimmune diseases. It also has a lipid lowering effect and is used as an anti-hyperlipidemic agent. Benzyl N-ethylcarbamate binds to 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which catalyzes the conversion of HMG CoA to mevalonic acid. This binding inhibits the conversion and prevents cholesterol synthesis by inhibiting the enzyme’s activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Phenoxybenzo[d]thiazol-2-amine is a benzothiazole that modulates the membrane potential and dilates blood vessels. It has been shown to lower blood pressure in vivo studies, and has been shown to be a neuroprotectant in murine models of stroke. 6-Phenoxybenzo[d]thiazol-2-amine also activates calcium channels, which may potentiate its effects on blood pressure.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Prop-2-yn-1-yl)pent-4-ynoic acid is an organic solvent that is activated with a molecule of argon. It has been shown to have affinity for malonic acid, which may be due to its ability to form hydrogen bonds with the carboxyl group on the ligand. 2-(Prop-2-yn-1-yl)pent-4-ynoic acid has also been shown to be nonpolymeric, which means it does not form long chains or rings of molecules. This makes it ideal for use as a ligand in pharmaceuticals and biochemistry. 2-(Prop-2-yn-1-yl)pent -4 -ynoic acid can be used as a binding agent in lithography because it can bind to both monomers and other agents. Research has shown that this chemical is able to increase serum glucose levels in hyperglycemic rats by inhibiting gluconeogenesis and glycogenolysis,</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>