Building Blocks

<p>Versatile small molecule scaffold</p>

<p>3-[(Piperidin-4-yl)methoxy]pyridine is a stilbene derivative that can be used to inhibit the activity of human pathogens. It has been shown to inhibit histone lysine methyltransferase (KMT) and lysine residues in the human cancer cells. 3-[(Piperidin-4-yl)methoxy]pyridine may also be a potential drug target for cancer, leukemia, and viruses. It is structurally related to piperidine and has a chemical formula COCHN. This compound inhibits tumor growth in animal models by targeting cellular proteins such as histone H3.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Ethynyl-2-fluoropyridine is a heterocyclic aromatic compound that is used in the synthesis of benzofurans. It can be prepared by reacting 3-ethynylaniline with bromine in the presence of potassium carbonate and then adding nitroethane. The yield of this reaction is 60%.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks the synthesis of viral DNA and RNA. It is used in combination with other drugs to treat HIV infection. Nevirapine has an inhibitory potency of 10 μM against HIV-1, HIV-2, and SIV. The chemical stability of nevirapine is greater than that of other NNRTIs such as delavirdine or efavirenz. Nevirapine has been shown to be active against drug resistant strains of HIV, such as the CXCR4 tropic virus strain BaL, but not against X4 tropic strains such as NL4-3 or IIIB. Nevirapine inhibits cell growth at concentrations ranging from 0.1 nM to 100 μM and has shown potent inhibitory activities against human leukemia cells and cancer cell lines in cell based assays.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,6-Dibromopyridine-4-carbonitrile (2,6-DBPC) is a chemical compound with two bromine atoms and one carbon atom on each of the two pyridine rings. The bromine atoms are often used to form a probe for hydrostatic pressure and as a ligand in organic chemistry. 2,6-DBPC is also used as a luminescent material, which can be used to measure the hydrostatic pressure that is exerted on it. This chemical has been found to have excellent photophysical properties such as high quantum yield and good responsiveness. It also has excellent luminescence properties, such as high emission efficiency and long lifetime. The molecular structure of 2,6-DBPC is similar to that of other compounds with lanthanide ions in their structures. These include terbium(III) tris(2,6-dibromopyridine)chloride (Tb3+), euro</p>

<p>5-(Aminomethyl)thiophene-2-sulfonamide is a potent inhibitor of carbonic anhydrase. It is used as a research tool to study the active site, affinity and isoenzymes of carbonic anhydrase. The inhibition of this enzyme by 5-(Aminomethyl)thiophene-2-sulfonamide leads to a decrease in the rate of reaction between water and carbon dioxide, resulting in decreased acidity in tissues. The molecular modelling parameters for this drug are C=0.25, H=0.75, N=1.00, Cl=0.50, O=1.00 and S=1.00. These values correspond to the number of atoms present in the molecule and their respective charges and masses on the periodic table (C: 12+, H: 1+, N: 14+, Cl: 35+, O: 16+, S: 32+).</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromo-1H-pyrrole-2-carbaldehyde is a natural product that belongs to the porphyrin family. It has a broad spectrum of biological activity, including the ability to form decahydroporphyrins, hydroporphyrins, chlorins and dodecahydrochlorins. 3-Bromo-1H-pyrrole-2-carbaldehyde has been shown to have antioxidant properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Fmoc-N-(propargyl)-glycine (Fmoc-PG) is a synthesized and modified amino acid that can be used in the treatment of cancer. Fmoc-PG has been shown to inhibit the growth of tumor cells when conjugated with positron emission radiotracers, such as 18F-Fluorodeoxyglucose, for use in positron emission tomography. Fmoc-PG also inhibits the glucose analogue, which may lead to an improvement of neurological function. Fmoc-PG has been shown to be metabolized by acid conjugates and conjugates, resulting in increased stability and reduced toxicity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>