Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,6-Dichlorophenylacetamide is an acetamide derivative with vasodilatory activity. It is a potent antihypertensive agent that can be used as a substitute for pyridazine. 2,6-Dichlorophenylacetamide also has the ability to contract vascular smooth muscle cells in vitro and in vivo. This drug has been shown to have antihypertensive effects in animal models of hypertension and to cause vasodilation in humans.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-3,5-pyridinedicarbonitrile (APDC) is a small molecule that has been shown to bind to the adenosine A1 receptor with high affinity and selectivity. It has a molecular weight of 167.2 g/mol, a pK of 7.4 and a logP value of 2.8. APDC was first synthesized in 1963 by scientists at the National Institute for Medical Research in London. The chlorine atom is influential in the pharmacokinetics of this compound. The pharmacokinetic profile shows that APDC is poorly absorbed and eliminated quickly from the body, with an elimination half-life of 0.6 hours and an oral bioavailability of less than 1%. This drug also has multipotent effects on Alzheimer's disease, showing significant efficacy against both plaques and tangles in animal models of Alzheimer's disease.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-[(Methylamino)methyl]phenol is a metabolite of 4-aminobiphenyl, which is found in cigarette smoke and other combustion products. It is an end product of the oxidative metabolism of polycyclic aromatic hydrocarbons (PAHs). This chemical has been shown to cause cancer tissue damage in lung cells and metabolic disorders in mice. The thermal expansion coefficient of 4-[(methylamino)methyl]phenol has been measured on calf thymus DNA and found to be similar to that of water. Chronic exposure to this chemical causes an increase in body mass index, increased risk for cardiovascular disease, and increased risk for atherosclerosis. Studies have shown that 4-[(methylamino)methyl]phenol can be eliminated from the body with a half-life of about 8 hours. Logistic regression analysis showed that high-sensitivity C-reactive protein (hsCRP) levels are significantly higher in people who are</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>7-Bromo-5-methoxyquinoline is a methoxide that is used as a starting material in the synthesis of other organic compounds. The condensation reaction with glycerol to produce 7-bromo-5-methoxyquinoline has been investigated using microwave irradiation. The yield was low, but the reagents were inexpensive and readily available.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Iodo-6-methylpyrimidine is a pyrimidine derivative that is used as a germicide. This compound has been shown to be catalytic and to have an expressed activity against halogenated compounds. 4-Iodo-6-methylpyrimidine can be used to produce ethers, chlorides, and aminopyrimidines by reacting with diethyl ether, chloride, or amine respectively.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-2-(1H-1,2,3-triazol-4-yl)phenol is a chemical compound that has been used in the diagnosis of cancer. It has also been shown to have protease activity and may be useful for structural biology. 4-Chloro-2-(1H-1,2,3-triazol-4-yl)phenol inhibits mitochondrial protein synthesis by binding to the hepg2 cell site and preventing the formation of disulfide bonds. The lack of expression of this protein in cancer cells leads to a reduced prognosis. This drug has also been shown to affect body mass index due to its effects on calcium binding.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-4-iodo-3-methylpyridine is a heterocyclic compound that belongs to the class of α-amino acids. It is a scalable, dehydroalanine derivative that has been shown to be an efficient catalyst for organic synthesis. This heterocycle has been used in the synthesis of several heterocycles, including pyridines, ketones, and acid derivatives. 2-Chloro-4-iodo-3-methylpyridine has also been shown to be enantioenriched and regiospecific.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methyl-3-(trifluoromethyl)-1H-pyrazole is a nitro, methoxy, cyano, chlorine, trifluoromethyl, trifluoromethoxy, halogenated pyrazole fungicide. The substituents on the molecule are methyl and trifluoromethyl groups. 4-Methyl-3-(trifluoromethyl)-1H-pyrazole is a potent inhibitor of fungal growth with a broad spectrum of activity. It has been used in agriculture as well as in the treatment of dermatitis caused by Candida albicans.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>