Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Bromo-4-(trifluorovinyloxy)benzene is a polyether that can be used to synthesize fluorescent polymers. The vinylene group in 1-bromo-4-(trifluorovinyloxy)benzene has shown to act as a nucleophile and yield polymerized products. This compound is insoluble in organic solvents, which makes it difficult to isolate yields. It has been experimentally shown that the anomeric carbon in this compound can be converted into the alpha form by treatment with potassium bis(trimethylsilyl)amide and then subjected to Wittig reaction.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Oxaspiro[4.4]nonan-6-one is a geometric isomer of the bicyclic compound 1,3,5-trioxaspiro[4.4]nonane. It has been synthesized by reacting 3-methylcyclohexanone with nitroethane in the presence of sodium ethoxide and potassium hydroxide. The substituents on the ring have been found to have an effect on the selectivity of 1-oxaspiro[4.4]nonan-6-one. For example, steric effects are more significant in this compound than in other six-membered rings with substituents that are not axial or equatorial. In addition, 1-oxaspiro[4.4]nonan-6-one has been shown to be a stronger diastereoselective agent than other six membered ring compounds with substituents that are not axial or equatorial due to</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Tert-Butyl 3-cyclopropyl-3-oxopropanoate is an organic compound that is used as a fungicide. It has been shown to be effective against fungi such as Botrytis cinerea, Phytophthora, and Pyricularia oryzae. Tert butyl 3-cyclopropyl-3-oxopropanoate inhibits the synthesis of ergosterol in the cell membrane by blocking its conversion to squalene. This prevents the formation of a sterol nucleus, which is required for the synthesis of dolichols and other important cell components.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Ethoxy-4-isocyanobenzene is a cyclized compound that is the product of an amidation reaction. It can be synthesized by reacting aniline with sodium ethoxide in ethanol. 1-Ethoxy-4-isocyanobenzene has been used as a precursor for the synthesis of other compounds, including azides, trimethylsilyl adducts, and ethylenediamine condensation products. Amidation reactions are spontaneous and occur without the need for a catalyst or external heat.</p>

<p>Cycloheptyl isocyanide (CIP) is a carbonyl group that can be used as a ligand in organometallic chemistry. It has shown to react with silicon, carboxylate, phosphite, and iron catalyst to form a ruthenium complex. The CIP reacts with Grignard reagents and cyclopentadienyl to form an imine. This organic compound is insoluble in organic solvents and can be used for hydrocarbon synthesis. Cycloheptyl isocyanide has been shown to react with organic compounds such as phenols, amines, and alkenes at room temperature.</p>

<p>2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(thiophen-2-yl)propanoic acid is a potent inhibitor that binds to the epoxide hydroxyl group of phospholipase A2. It has been shown to interact with solid phase synthesis and synthetic methods for evaluation of epoxide hydroxylation reactions. This compound was synthesized using fmoc-gly-oh as the protecting group, which is then removed by transition metal catalyzed ligand exchange. 2-[(9H-fluoren-9-yl)methoxy]carbonylamino]-3-(thiophen-2-yl)propanoic acid can be used in the treatment of inflammatory conditions such as asthma or arthritis.</p>

<p>5-(2,4-Dichlorophenyl)-2-furoic acid is an antibacterial agent that has been shown to have a cytotoxic effect on tumor cells. The biological activity of this compound has been shown in vitro and in vivo. 5-(2,4-Dichlorophenyl)-2-furoic acid has been found to inhibit the growth of tumor cells by interfering with their metabolism and inhibiting the synthesis of DNA, RNA and proteins. 5-(2,4-Dichlorophenyl)-2-furoic acid also inhibits the growth of microorganisms such as Enterococcus faecalis. This antibiotic has been shown to destroy bacterial cell walls by oxidation of chitin at the interface between the cell wall and cytoplasmic membrane. The mechanism for this action is not yet clear, but it may involve photoelectrical effects or generation of reactive oxygen species.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(2-Chloroquinazolin-4-yl)amino]ethan-1-ol (CQAEE) is a prodrug that is enzymatically hydrolyzed in vivo to the active form CQAE. It is an inhibitor of carbonic anhydrase enzymes and has been shown to be more potent than amiodarone and less toxic than acetazolamide. CQAEE has been shown to be effective in vitro against human erythrocytes, homopolymers, and amiodarone, but not in vivo against congestive heart failure. The process of hydrolysis by enzymes causes the release of a carboxylic acid and ethylene glycol which are responsible for the observed therapeutic effects. The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an antituberculosis drug that belongs to the class of rifamycins</p>

<p>Versatile small molecule scaffold</p>

<p>5-(Bromomethyl)-3-(propan-2-yl)-1,2-oxazole is an aminoisoxazole that can be used as a precursor for the synthesis of hydroxylamine. It is also used to synthesize a hydroxylamine hydrochloride (HNHCl) salt. 5-(Bromomethyl)-3-(propan-2-yl)-1,2-oxazole is soluble in water and can be isolated by extraction with organic solvents.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>