Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Iodomethyl)tetrahydro-2H-pyran is a synthetic cannabinoid that has been shown to bind to the CB2 receptor. It has been shown to have cannabimimetic properties and has been used as a research tool in drug product development. 4-(Iodomethyl)tetrahydro-2H-pyran has been found to have an EC50 of 2.6 μM for the CB2 receptor, which is higher than the EC50 for other synthetic cannabinoids (1.5 μM). This drug also binds to the cb1 receptor and can be used as a research tool in drug discovery.</p>

<p>2-[Benzyl(methyl)ao]propanoic acid is a glycine analogue that has been synthesized and characterized. It is an α-amino acid with the chemical formula C5H11NO2. The molecule has a chiral carbon atom at the center of the propanoic acid group and contains two asymmetric carbon atoms on the benzene ring, which enable it to exist in two stereoisomers. The compound has been shown to exhibit interligand interactions with copper as well as stereoselectivity in its interactions with l-amino acids. 2-[Benzyl(methyl)ao]propanoic acid also exhibits dichroism spectra, which are unique to these types of molecules.</p>

<p>BIX is a redox potential-indicating reagent that has been used in the study of physiological effects and mechanisms. It is also an autophagy inducer and methyltransferase inhibitor. BIX has been shown to induce caspase-independent cell death in metastatic colorectal cancer cells. This agent has been used as an effective chemotherapy for hypoxic tumor cells and HIV infection, as well as for the treatment of plant physiology. BIX is a monosodium salt that is soluble in water and ethanol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,3-Dihydro-5(1H)-indolizinone (NU-120) is a quinoid compound that has been shown to have anti-oxidant and anti-inflammatory properties. The prodrug form of NU-120 is converted to the active n-oxide form in vivo by the enzyme cytochrome P450. This conversion takes place at an efficient rate with oral absorption between 0.2% and 2%. The drug has a crystalline structure and solvates readily in water.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Iodo-2-methoxypyrimidine is an enantioenriched, modular, polyfunctionalized, derivatized molecule that has been shown to be both antiproliferative and selective. It is synthesized in a two step reaction from acetate and 2-iodo-5-methoxypyridine via the use of a coupling agent, such as HATU. The synthesis proceeds with an arylation followed by a decarboxylative coupling reaction. This synthetic method produces 5-iodo-2-methoxypyrimidine in high yields with excellent enantioselectivity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methylfuran-3-carboxylic acid (MF) is a corticosteroid that is synthesised from the natural hormone, cortisol. It has been shown to have a number of biological properties, such as anti-inflammatory and anti-allergic effects. MF has been used in rodents to study its effect on various organs, including the adrenal gland, liver, kidney, heart, and spleen. This drug has also been shown to have anabolic effects on rats. MF is used in medicine for the treatment of asthma and other inflammatory conditions.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromo-2-chloroquinoline is an isomeric compound that has been shown to have anticancer properties. It is able to bind to amines, which are present in the cell membranes of cancer cells and alter their conformation. This leads to a change in the permeability of the membrane and leads to the death of cancer cells. 3-Bromo-2-chloroquinoline also binds to nucleophilic sites on DNA, including guanine, adenine and thymine. The molecule can also be synthesized from 3-bromoquinaldine by reacting with chlorine under basic conditions. 3-Bromo-2-chloroquinoline has been found as a natural product in plants such as "Ligusticum chuanxiong" (Chinese lovage).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-4-(chloromethyl)pyridine is an inhibitor of lipoxygenase, which is an enzyme that catalyzes the conversion of polyunsaturated fatty acids to hydroperoxides. 2-Chloro-4-(chloromethyl)pyridine inhibits the activation of these fatty acids by blocking the reaction with hydrogen chloride and nitrite, thereby reducing inflammation and pain. 2-Chloro-4-(chloromethyl)pyridine also has a neutralizing effect on inorganic bases such as ammonia.</p>

<p>2-Amino-1-cyclohexylpropan-1-ol is an organic compound that belongs to the group of aromatic amino acids. It is a precursor to other chemicals, such as ethylene glycol and phenylglycine. 2-Amino-1-cyclohexylpropan-1-ol can be used as a catalyst for the reduction of ethylmalonic acid. Catalytic reduction of ethylmalonic acid produces acetaldehyde, which can be used in the production of acrylic acid and polymers. 2-Amino-1-cyclohexylpropan-1h has been shown to yield higher yields than catalytic reduction with rhodium or platinum metals.</p>

<p>5-Amino-N-(2-chlorophenyl)-2-methoxybenzene-1-sulfonamide is a reagent for the study of protein interactions and ion channels. It can be used as a research tool for cell biology, pharmacology, and receptor research. 5-Amino-N-(2-chlorophenyl)-2-methoxybenzene-1-sulfonamide has been shown to bind to an antibody. This compound is a ligand or activator that binds to receptors. The chemical name of this compound is (5R*,6R*)-N-[(5S*,6S*)-6-[(5R*,6R*)-5-(aminomethyl)-2,4,6-trimethylphenyl]-3,3'-dimethylbicyclo[3.1.0]hexan]-6'-carboxamide hydrochloride monohydrate. It</p>

<p>Versatile small molecule scaffold</p>

<p>2-({5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl}sulfanyl)benzoic acid is a synthetic nonpeptide compound that belongs to the group of ligands. This inhibitor binds to nicotinic acetylcholine receptors and inhibits their activity. 2-({5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl}sulfanyl)benzoic acid has been shown to be a potent activator of these receptors. This compound also inhibits voltage dependent potassium channels and calcium channels.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-[4-(Morpholine-4-sulfonyl)-2-nitrophenyl]piperidine-4-carboxylic acid is a research tool that has been used to study the mechanism of ion channels and ligand binding. It also has been shown to be an antagonist for the nicotinic acetylcholine receptor, which may be due to its ability to bind competitively to the receptor site and prevent acetylcholine from binding. This compound has not been observed to have any effects on protein synthesis or cell proliferation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>