Building Blocks

<p>(2-Ethylphenyl)methanamine is an analog of fluconazole, a drug used to treat fungal infections. It has been shown to have potentiation properties that are similar to those of fluconazole. The mechanism of action involves inhibiting the efflux pump in the cell membrane. This leads to increased intracellular concentrations and enhanced activity of fluconazole against Candida albicans.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Iodo-2-methylbut-1-ene is an alkylating agent that forms a covalent bond with DNA. It can be synthesized by the reaction of an electrophile, such as methyl iodide, with an enone. This process is stereoselective and stereoselectively mediated. The compound is used in the synthesis of pheromones and has been shown to have cytotoxic effects on tumor cells. 4-Iodo-2-methylbut-1-ene can be synthesized by the catalysis of trifluoromethanesulphonate. When this reagent reacts with an organic molecule containing a reactive group, it forms a covalent bond with DNA and inhibits protein synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Bis(2,2,2-trifluoroethyl) sulfite is an additive that enhances the performance of water-based inks and coatings. It is a colorless liquid with a low viscosity and high volatility. Bis(2,2,2-trifluoroethyl) sulfite is used as an additive to increase the solubility of other additives in water-based ink and coatings formulations. It has been shown to enhance the performance of these formulations by improving wetting properties. This additive also has been shown to reduce surface tension and improve gloss. The mechanism of action for this compound is not well understood but may be due to its ability to form hydrogen bonds and/or ionic interactions with molecules on the substrate surface.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Chloro-5-methylphenoxymethyl)oxirane is an enantiopure chemical compound. It is racemic and has two possible configurations: (R)-2-(2-chloro-5-methylphenoxymethyl)oxirane and (S)-2-(2-chloro-5-methylphenoxymethyl)oxirane. The enantiopence of 2-(2-chloro-5-methylphenoxymethyl)oxirane can be determined by recrystallization, crystallization, xray diffraction, or by entrainment methods.</p>

<p>Methyl 3-(Hydroxymethyl)-5-nitrobenzoate (HMB) is a maleimide that is used in the synthesis of amino-substituted azides. It was expressed as a recombinant protein in Escherichia coli and purified by solid-phase synthesis. The protein has been shown to bind to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibit cell growth in culture.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Iodobenzene-1-sulfonamide is a benzothiazine derivative that has been synthesized and its characteristics have been studied by molecular modeling. It has shown potential as an anti-inflammatory drug candidate. The pharmacophore of 2-iodobenzene-1-sulfonamide is composed of two amines, terminal alkynes, and a ligand. This molecule also showed activity against Cox-1 and Cox-2 enzymes, which are responsible for the production of prostaglandins and thromboxanes in the body. This study revealed that 2IBS is an efficient method to inhibit COX enzymes.</p>

<p>2-[(5-Mercapto-1,3,4-thiadiazol-2-yl)thio]acetic acid (MTTSA) is a fluorescent probe that emits light at a wavelength of 590 nm when irradiated with light. MTTSA has been synthesized using gold nanoclusters as the catalyst. The average diameter of the nanoclusters was determined to be in the range of 2.0 - 3.0 nm, and their average quantum yield was found to be 0.097%. The emission wavelengths can be tuned by varying the size of the nanoclusters. When MTTSA is irradiated with UV radiation, it undergoes photocatalysis and converts organic matter into water and carbon dioxide gas.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(4-Nitrophenyl)propyl bromide (3NPPB) is a bifunctional ligand with antiproliferative activity. It is able to bind to the alpha subunit of human hepatocellular carcinoma (HCC) receptors, inhibiting the growth of cancer cells. 3NPPB has been shown to be effective in animal models for HCC and other cancers. 3NPPB is a metal chelator with a high binding affinity for copper, and it has been shown to reduce the level of copper in liver tissue.</p>

<p>4-Cyclopropyl-4-oxobutyric acid is a methanolic glutamic alkylation lactone that has been shown to be an asymmetric sodium salt. The nitriles of 4-cyclopropyl-4-oxobutyric acid are hydrolyzed to form the corresponding acids, which are then debenzylated to form the corresponding alcohols. This process is catalyzed by nitrile hydratase and oxidized by alcohol dehydrogenase. The bicyclic structure of 4-cyclopropyl-4-oxobutyric acid can be formed by condensation of two molecules of acetaldehyde and one molecule of malonic acid.</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Propan-2-yloxy)pyridine is an isomer of pyridine, a heterocyclic organic compound with the chemical formula C5H7N. It contains a benzene ring fused to a pyridine ring. The compound is of interest as a model system for studying asymmetric synthesis because it can be synthesized in two forms that are mirror images of each other. The molecule has been shown to be metastable and deuterium can be used as a shift reagent to reveal its chirality. 4-(Propan-2-yloxy)pyridine has also been shown to have antimicrobial properties against bacteria such as methicillin-resistant Staphylococcus aureus (MRSA).</p>

<p>2,5,5-Trimethylhexanoic acid is a fatty acid that is used as an additive for lubrication, plasticizers, and esterifying agents. It is a mixture of 2-ethylhexanoic acid (2EHA) and 2-methylpentanoic acid (2MP). The chain length of the molecule ranges from C10 to C22 with a majority of the chains being in the range of C14 to C18. The alkyl group has two carbon atoms. This fatty acid can be found in natural sources such as animals and plants or it can be produced synthetically.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methoxy-5-phenylpyridine is a carbamate inhibitor that has been shown to be a potent and selective inhibitor of the enzyme acetylcholinesterase (AChE). It has been used for labeling, optimization, and identification of new AChE inhibitors. 2-Methoxy-5-phenylpyridine has also shown activity against the enzyme butyrylcholinesterase. This compound can be used as a test compound in tissues, such as the nervous system, or in cell cultures.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylheptanoic acid is an achiral, volatile fatty acid that is found in the urine and feces of mammals. It has been shown to be a potent skatole inducer, and is capable of producing abdominal pain. 3-Methylheptanoic acid has also been shown to bind competitively to the receptor site for dimer (2,3-dimethoxy-5-methylphenol) in the antennae of cockroaches and other insects. This binding inhibits electroantennographic responses, which are used as a measure of insect activity. 3-Methylheptanoic acid can be used as an indicator for orthophosphoric acid in chemical analysis. The optical rotation of this compound is determined by its configuration at the asymmetric carbon atom. This functional group allows 3-methylheptanoic acid to act as an antiseptic and germicide when it reacts with water or dilute acids to form orthophosph</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Ethenyl-1H-indole is an organic compound that can be synthesized from a Friedel-Crafts reaction of a fatty acid and an alkyl halide. The cycloaddition process of 2-ethenyl-1H-indole to form the bicyclic system was found to proceed through a [4+2] cycloaddition mechanism with the formation of a strained six membered ring between the two carbon atoms at the junction. This product is then converted into biofuels, such as particle or fatty acids, by analytical chemistry. Preparative high performance liquid chromatography (HPLC) has been used to separate glycogen synthase kinase 3 (GSK3) oligosaccharides, which have been shown to be involved in various biological processes.</p>

<p>Propyl (2S)-2-hydroxypropanoate is a neurotoxic chemical that can cause hydrolysis or long-term exposure to lead to neurotoxicity. Exposure to this chemical can lead to neurobehavioral changes and encephalopathy, which may be due to its effects on the central nervous system. It has been shown that propyl (2S)-2-hydroxypropanoate can also interfere with lactic acid metabolism, leading to an accumulation of lactic acid in the body. This accumulation may contribute to a variety of neurological symptoms seen in patients who have ingested this chemical, including psychoactive effects and organic solvent syndrome.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Chloro-4-methyl-1,2,3-thiadiazole is a long chain derivative of thiadiazole. It has been found to have anticancer activity in vitro against prostate cancer cells. 5-Chloro-4-methyl-1,2,3-thiadiazole inhibits the growth of cancer cells by blocking fatty acid metabolism and inhibiting the production of carnitine. This agent also induces carboxyamide reductase and alcohol dehydrogenase activities in vitro. The anticancer effect is not restricted to prostate cancer cells; it has also been shown to inhibit human glioma cell proliferation in vitro.</p>

<p>5-Methylpyridine-2,3-dicarboxylic acid is an organic compound with the formula CH3C6H4(CH2)4O2. It is a white crystalline solid that is soluble in water and ethanol. 5-Methylpyridine-2,3-dicarboxylic acid is a ligand for alkali metal ions. It has been used to synthesize a number of compounds with different properties, such as methoxymethyl, fluorescence properties and ammonium nitrate. The structures of the isomers can be determined by x-ray diffraction techniques and by gravimetric analysis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Vinyl-dihydrofuran-2(3H)-one is a cyclopropanecarboxylic acid that can be synthesized using the refluxing of an alkali metal hydroxide, such as potassium hydroxide, with an alcohol. The reaction produces a cyclopropanecarboxylic acid and water. 4-Vinyl-dihydrofuran-2(3H)-one is used as an insecticide as well as in the synthesis of other chemicals. It has been shown to have anticholinesterase activity.</p>

<p>4-(4-Ethoxyphenyl)-4-oxobutanoic acid is a ketone that has been found to be biologically active. It is a heterocyclic compound that contains a benzene ring and a heterocyclic aromatic ketone. The crystal structure of 4-(4-Ethoxyphenyl)-4-oxobutanoic acid has shown the presence of hydrogen bonds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Butyl-1-carbamimidamido-N'-ethylmethanimidamide hydrochloride is a conjugate of an amide and fatty acids. It has been used for the treatment of prediabetes, hyperlipidemia, and heart disease. N-Butyl-1-carbamimidamido-N'-ethylmethanimidamide hydrochloride has structural formula C14H27NO4. It is a fatty acid ester that can be found in the tissues of animals and humans. This drug binds to the apolipoprotein A1 receptor, which is involved in cholesterol metabolism. N-Butyl-1-carbamimidamido-N'-ethylmethanimidamide hydrochloride also inhibits the enzyme lipoxygenase, which produces fatty acids from polyunsaturated fatty acids. This drug may cause irritation to skin or mucous membranes because it contains irritants such as ethanolamine and but</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Benzoxazole-2,4-diol is a reactive compound that can be activated by catalase or other reducing agents. It has been shown to modulate the biochemical reactions of cells, and is used in medicines as an antioxidant. 1,3-Benzoxazole-2,4-diol is also able to activate the nuclear factor erythroid 2-related factor 2/heme oxygenase 1 (Nrf2/HO-1) signaling pathway. This activation leads to the production of proteins such as collagen and glutathione that are important for wound repair. The reactive properties of 1,3-benzoxazole-2,4-diol have also been shown to be effective in treating muscle damage in animals. 1,3-Benzoxazole-2,4-diol has been shown to have antiinflammatory effects due to its ability to inhibit the production of malondialdehyde and serum al</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 3-formylfuran-2-carboxylate is a selective, triethyl, acrylates, carbonyl groups, phosphite, chloride, carbonyl, diisopropyl, phosphonates, fluoride, potassium and phosphites. It reacts with isomeric hydroxyphosphonates.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>