Building Blocks

<p>1-(3-Hydroxypropyl)-2,5-dihydro-1H-pyrrole-2,5-dione is a monomer that has been used for the fabrication of polymers. It is a colorless liquid with a boiling point of 109.7°C and a melting point of -37.6°C. It can be reversibly polymerized with formaldehyde to give poly(1-(3-hydroxypropyl)-2,5-dihydro-1H-pyrrole-2,5-dione). The compound can be purified by gel permeation chromatography or recrystallization. 1-(3-Hydroxypropyl)-2,5-dihydro-1H-pyrrole-2,5-dione can also be used as an intermediate in the synthesis of other compounds such as phenoxyacetic acid and methyl 2-(3'-hydroxyphenoxy)</p>

<p>Mal-PEG2-OH is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, mal-PEG2-OH is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.</p>

<p>N-(2-Methoxyethyl)ethylamine is a chlorinated organic compound that is used as an adsorbent for the removal of chloride ions from wastewater. It can be prepared by reacting ethylamine with chloroform in the presence of a catalytic amount of acetone. The resulting product has a high affinity for chloride ions and has been shown to be effective in removing chloride from water contaminated with chlorinated solvents such as benzene, methyl alcohol, n-hexane, tetrachloride, carbon tetrachloride, and chloroform. N-(2-Methoxyethyl)ethylamine is insoluble in water or organic solvents. It also exhibits good thermal stability at temperatures up to 200°C.</p>

4-Chlorophenyl-[4-(trifluoromethyl)phenyl]methanone (TFMPP) is a psychostimulant drug that binds to the serotonin 5-HT2A receptor. TFMPP has been shown to produce effects in wild-type mice similar to those of amphetamine, but not in mice with the 5-HT2A receptor gene knocked out. The effective dose for TFMPP was determined by measuring the effect on extracellular dopamine levels in rat striatal tissue. TFMPP also inhibits the activity of an enzyme called adenosine deaminase, which breaks down endogenous adenosine. This inhibition leads to increased concentrations of adenosine and allosteric modulator binding at the 5-HT2A receptor site. TFMPP has also been shown to bind to a site on the G protein called Gαi3 and stabilize it, which may explain its ability to inhibit adenosine de

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2E)-1-(Furan-3-yl)-4-methylpent-2-en-1-one is a natural compound that has been shown to have cytotoxic effects on HL60 cells. This compound has been found to induce cell lysis and caspase-independent cell death in HL60 cells, which may be due to its ability to inhibit the activity of transcription factors such as nuclear factor kappa B (NFkB) and activator protein 1 (AP1). It also inhibits the activity of toll-like receptor 4, which is a protein that plays an important role in immune response. In addition, this compound has been shown to be able to induce apoptosis in cancerous cells by interfering with the expression of proteins related to DNA synthesis and metabolism.</p>

<p>2-(4-Biphenylyl)-2-propanol (BPP) is a crystalline compound that has a density of 1.3 g/cm3 and a melting point of 189°C. It has a nonplanar conformation with the hydrogen bond forming dihedral angles of 36° and an asymmetric shape. The functional theory predicts that BPP will have high reactivity, which is confirmed by gas phase experiments.</p>

<p>2-Phenylpropane-1-thiol is a molecule that is used as an intermediate in the synthesis of other compounds. 2-Phenylpropane-1-thiol can be used to measure mitochondrial membrane depolarization, which is a characteristic of bioenergetic dysfunction. This compound has been shown to inhibit the growth of ges-1 cells, which have been shown to have a high level of resistance to apoptosis induced by chemotherapeutic drugs. 2-Phenylpropane-1-thiol may also act as a ligand for proteins, although it has not been confirmed. The diameter of this molecule is 1.69 angstroms.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid is a hypocholesterolemic agent that has been shown to lower plasma cholesterol levels in the rat model. This compound is an analog of propionate, a known hypocholesterolemic agent. 5-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid is converted by esterases to its active form, 1,4-benzoquinone dioxane 2 carboxylic acid (BQDCA). The structural similarity of BQDCA with propionate suggests that it may have similar biological activities. 5-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid also possesses some antihyperlipemic activity and has been shown to inhibit the synthesis of triglycerides in rat liver cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,3-Dimethyl-1-(piperidin-4-yl)urea dihydrochloride is a synthetic compound that is used as a building block in the synthesis of oligosaccharides. It is also a potential drug candidate for the treatment of metabolic disorders such as diabetes mellitus and obesity. 3,3-Dimethyl-1-(piperidin-4-yl)urea dihydrochloride is an example of a carbohydrate that has been fluorinated to increase its stability. This modification can be accomplished through methylation or glycosylation. The compound can be modified using a click chemistry reaction to attach it to other compounds.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold