Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Iodoquinoxaline is a heterocyclic compound that contains an ethyl diazoacetate group. It can be synthesised from chloroformate and ferredoxin, which are both five-membered rings. 2-Iodoquinoxaline is used to make other heterocyclic compounds, such as the phosphonium salt and the dioxolane. This molecule has also been shown to be a good acceptor for evaporation of liquids. When exposed to radiation, 2-iodoquinoxaline converts into a molybdenum (Mo) molecule, which is important in the synthesis of many organic compounds. This compound can also be synthesized by reacting styrene with olefinic molecules under appropriate conditions.</p>

<p>Ethyl 4-amino-3-thia-1-azatricyclo[5.2.2.0,2,6]undeca-2(6),4-diene-5-carboxylate is an acylated amino acid that contains a cyanoacetic acid moiety with an elemental sulfur atom in the side chain. It is used in the production of acrylamide and as a precursor to various pharmaceuticals, pesticides, and dyes.</p>

<p>1-(1,3-Benzothiazol-2-yl)propan-2-one is a type of benzene compound with substituent groups. It has the formula CHCHS. The substituents are methyl and acetate. The benzene ring is substituted with two substituents in the coplanar arrangement. Benzene rings can form condensation products through a process called electrophilic substitution. This process involves the addition of an electron pair to an atom or molecule by an electrophile to form a covalent bond. One example of this reaction is the formation of methyl acetate from 1-(1,3-benzothiazol-2-yl)propan-2-one by heating it with methanol.</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Benzyloxy)-2,2-dimethylpropanoic acid (BPD) is a carboxylic acid derivative that is used as a reagent in organic synthesis. It is also used to acylate fatty acids to form esters or amides. BPD is also used in the preparation of anhydrides and halides.</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,3,4-Tetrahydroquinolin-5-amine (1,2,3,4-THQ) is a hydrazine derivative that has been used in organic synthesis as a reagent for the reductive amination of amines. It is also used as a precursor for the synthesis of other heteroaromatic compounds. The 1,2,3,4-THQ can be prepared by condensation of aniline with nitroethane and phenylenediamine in the presence of Raney nickel. Analogous reactions have been reported using benzylamine derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl N-(chlorosulfonyl)carbamate is a potential drug candidate that was developed to inhibit the activity of peptidases, an enzyme that breaks down proteins. It has been found to inhibit the activity of a variety of peptidases and is stable at temperatures up to 80°C. This reagent is used for medicinal chemistry research and can be used as a starting material for optimization and structural studies. Methyl N-(chlorosulfonyl)carbamate has also been shown to inhibit the activity of other enzymes, such as epoxide hydrolase, which breaks down epoxides. This inhibitor may have therapeutic potential in diseases such as cancer or inflammation.</p>

<p>5-Chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone (CMTP) is a trifluoromethyl, chloro, fluoro, triazolyl compound. It is an intermediate in the synthesis of benzophenones and nitro compounds. CMTP can be synthesized by a multistep process from bromobenzene or chlorobenzene. This compound is used as a tranquilizer and sedative in the treatment of anxiety and insomnia.</p>

<p>2-Oxo-1,2-dihydroquinoline-3-carbonitrile is a chemical compound that is used as an antiallergic agent. It has been shown to inhibit the release of histamine from mast cells and also inhibits the release of prostaglandins from human platelets. The compound is synthesized by condensation of ammonium chloride with nitropropane in the presence of sodium azide. The x-ray analysis shows that this compound has a quinoline ring.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Aminoimidazole sulfate is a diazonium salt that is used as a contrast agent in radiological imaging. It has been shown to have potent antagonistic effects on the growth factor receptor tyrosine kinase. 2-Aminoimidazole sulfate can be administered orally or intravenously and is stable at pH values of 4.5 to 8. It is also used as an anticholinesterase agent, which prevents the breakdown of acetylcholine by inhibiting cholinesterases in the body. This drug has been shown to be effective in chronic bronchitis and asthma treatment, although it has not yet been approved for these purposes. 2-Aminoimidazole sulfate binds to proteins through covalent cross-linking reactions with amine groups on lysine residues, which inhibits protein function. This drug is also used in industrial wastewater treatment, where it reacts with ethyl eth</p>

<p>Versatile small molecule scaffold</p>

<p>2-(9H-Fluoren-2-yl)propanoic acid (2FP) is a fatty acid that has been shown to be effective in the treatment of diabetic patients. It is also used as an anti-inflammatory drug, and may have potential for the treatment of cardiac hypertrophy, cardiac arrhythmias, and inflammatory diseases. 2FP has been shown to inhibit the activity of cyclooxygenase enzymes and reduce prostaglandin synthesis. The biological properties of 2FP are similar to that of other nonsteroidal anti-inflammatory drugs (NSAIDs). 2FP has been found to be biocompatible with polymer materials, which means it can be used in diagnostic agents such as contrast agents for CT scans or PET imaging. The Friedel-Crafts reaction between 2FP and phenol yields para-nitrophenol, which reacts with mercury chloride to form a red dye called resorcinol. This dye can then be used as a</p>

<p>Versatile small molecule scaffold</p>

<p>5-Bromomethyl-3-methyl-isoxazole+ is an inhibitor of thymidylate synthase (TS). TS catalyzes the conversion of deoxyuridine monophosphate to dUMP and dihydrofolate. 5-Bromomethyl-3-methyl-isoxazole+ shows significant inhibition of cell proliferation, with a potency similar to that of the lead compound Lsd1. In addition, this inhibitor has good oral bioavailability in humans and does not show any cytotoxicity towards human cells. The IC50 for 5-bromomethyl-3-methyl-isoxazole+ is less than 1 nM.</p>

<p>5-(Bromomethyl)-3-ethyl-1,2-oxazole is a hydroxylamine derivative that has been used in the synthesis of amines. It reacts with primary amines to form oxazoles. This compound has also been shown to react with hydroxylamine to form an oxazole. 5-(Bromomethyl)-3-ethyl-1,2-oxazole is a white solid that can be synthesized by reacting aniline with bromoethane and ethylhydroxyamine in the presence of hydrochloric acid.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromoethylcyclopropane is a halide that has been shown to have an affinity for eosinophils and platelets. It is used in the synthesis of pharmaceuticals, including drugs to treat infertility, clotting disorders, and preeclampsia. 2-Bromoethylcyclopropane also has an affinity for the pyrrolidinyl and neurokinin receptors. The coordination complex of 2-bromoethylcyclopropane with copper(II) ions inhibits prostaglandin synthesis by binding to the prostaglandin synthase enzyme. This drug also solvates metal ions, such as copper(II), and forms stereoisomers with other organic molecules.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,4-Dioxoheptanoic Acid Ethyl Ester is a synthetic drug that is used to treat erectile dysfunction. It acts by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. The cGMP causes relaxation of the smooth muscle cells in this region, leading to increased blood flow and an erection. 2,4-Dioxoheptanoic Acid Ethyl Ester has been shown to be effective when taken with other drugs such as Sildenafil or Tadalafil. This drug has been approved for use in Canada and Europe and clinical data suggests it has a low incidence of serious adverse effects.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Methyl-2-(methylsulfonyl)benzimidazole is a reagent that reacts with carbonyl groups to form terminal alkenes. It can be used to form terminal alkenes from aldehydes and ketones by the addition of an appropriate nucleophile, such as sodium borohydride. The reaction has high yields and does not produce any byproducts.</p>

<p>4-(Hexyloxy)-3-methoxybenzaldehyde is an aldehyde that has a molecular weight of 166.14 g/mol and the following connectivity:</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

5-(Hydroxymethyl)-2-nitrophenol (5-HMNP) is a reactive intermediate in the catalytic mechanism of hydroxylation. 5-HMNP is produced by the reaction of an epoxide with a hydroxyl group. The isotope effect has been shown to be due to resonance stabilization, which stabilizes the molecule and prevents it from reacting further. 5-HMNP reacts with chloride ions to form phenols, which have been shown to have antioxidant properties.

<p>9-Methyl-9H-carbazol-3-amine is a synthetic amine that has been shown to have cytotoxic activity against human cancer cells in vitro. It inhibits the growth of cancer cells by binding to DNA and RNA. 9-Methyl-9H-carbazol-3-amine has been shown to be a fluorescent compound, with excitation and emission maxima at 337 nm and 438 nm, respectively. The fluorescence properties of 9-methyl-9H carbazole 3 amine are pH dependent, with maximal emission occurring at pH 5.5. 9MCCA is soluble in water and dodecyl alcohol but insoluble in organic solvents such as benzene or chloroform. It also has been found to have gel permeation chromatography (GPC) retention times of about 1 hour and a polyvinylpyrrolidone (PVP) molecular weight of about 40,000 daltons.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4,5-Dimethoxy-2-iodobenzoic acid is a diazo compound that belongs to the class of aryl ethyl compounds. It is an efficient method for the synthesis of unsymmetrical aryl ethyl compounds. This compound has been shown to have potent antitumor activity against experimental tumors in mice when given orally. 4,5-Dimethoxy-2-iodobenzoic acid inhibits tumor cell proliferation by blocking DNA synthesis and transcription. It also binds to receptor protein kinase C, which may be responsible for its antitumor activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>