Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Amino-1-benzyl-3-methylthiourea (MBT) is a cationic organosulfur compound with a trifluoroacetic acid moiety. It is also known as 3-aminobenzyl methylthiocarbamate or 3,3'-diacetylbenzyl methylthiocarbamate. MBT is a cyclized product of trifluoroacetic acid and phenylglyoxal, which has been used in the synthesis of various organic compounds. The chemical properties of MBT are similar to those of diacetyl and acetaldehyde, but it does not have the unpleasant odor associated with these substances. In addition, MBT does not react with proteins and is less toxic than other carbonyl compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-1-(4-methoxyphenyl)propan-1-one is a synthetic molecule that has been used to induce apoptosis in tumor cells. It reacts with ethanolamine to form 2,2'-dibromoethyl ether, which then reacts with nitrobenzene to produce the carcinogenic compound 4-nitrophenol. This compound induces apoptosis by inhibiting DNA synthesis and protein synthesis. The reaction time for this process is about 1 hour at room temperature. The structure of 2-bromo-1-(4-methoxyphenyl)propan-1-one is shown below:</p>

The asymmetric synthesis of cinnamyl chloride is achieved using a palladium-catalyzed coupling reaction. Cinnamyl chloride is a chiral compound that has been shown to have anti-inflammatory properties and inhibit acetylcholinesterase (AChE) activity. The enzyme inhibition mechanism of cinnamyl chloride is not well-understood, but it may be attributed to the allylation of the nitrogen atoms in the molecule. Cinnamyl chloride inhibits AChE by binding to its active site, which prevents the hydrolysis of acetylcholine, an important neurotransmitter for memory and learning. This leads to increased levels of acetylcholine in the brain and increases neuron activity.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>D-2-Amino-thiopheneacetic acid (DAT) is a non-selective endothelin receptor antagonist. It has an IC50 value of 2 nM for bq-123, an affinity that is mediated by receptor subtypes, and inhibits cyclic AMP production in the presence of hexapeptide. DAT was discovered as a cyclic peptide antagonist of the endothelin receptor. It binds to the same site on the endothelin receptor as endothelin itself, preventing it from binding to its receptors on cells in the body. This prevents activation of cellular responses to endothelin, such as vasoconstriction, which can lead to high blood pressure and heart disease. DAT also has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>8-Methoxyquinoline-2-carboxylic acid (8MQCA) is a carboxylate that has been shown to be an effective antibacterial agent. 8MQCA can inhibit the growth of bacteria by binding to the cell wall and inhibiting the synthesis of proteins, leading to cell death. The bactericidal effect of 8MQCA against Escherichia coli and Pseudomonas aeruginosa was demonstrated using a recording technique in which the inhibition of bacterial growth was measured as a function of time. It is also used as an additive in food packaging films and paperboard to prevent photofading. 8MQCA is stable at elevated temperatures and pH levels, making it suitable for use in food packaging materials.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-[(3-Aminophenyl)methyl]piperidin-2-one is a potent and selective activator of the N-type calcium channels. It has been shown to inhibit voltage-gated calcium channels by binding to the pore region of the channel, inhibiting the flow of ions into the cell. This drug has been used as a pharmacological tool in research on ion channels, ligand binding and antibody production.</p>

<p>5-Benzyloxolan-2-one is a flavanol that has been shown to inhibit the growth of Clostridium species. 5-Benzyloxolan-2-one is found in foods such as fructo-oligosaccharides and escherichia coli. In vitro studies have shown that this compound inhibits the utilisation of phenylpropionic acid by clostridia, leading to a significant inhibitory effect on their population. 5-Benzyloxolan-2-one also has prebiotic properties as it stimulates the growth of microflora populations in the gut.</p>

<p>Versatile small molecule scaffold</p>

<p>L-Homophenylalanine hydrochloride is a chemical substance that belongs to the group of aspartic acid. It can be synthesized by the Friedel-Crafts reaction between L-aspartic acid and hydrochlorides, anhydride, or acylating agent. L-Homophenylalanine hydrochloride is used in the preparation of various drugs such as analgesics, antiarthritic agents, antidepressants, antipsychotics, and antihypertensives.</p>

<p>2-(Pyridin-4-yl)-1H-indole is an antibiotic that functions as a proton pump inhibitor. It has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA). 2-(Pyridin-4-yl)-1H-indole has been shown to inhibit the growth of MRSA by cleaving bonds in peptidoglycan, which is an essential component of the bacterial cell wall. Although this drug has not yet been tested in humans, it could have clinical relevance because it inhibits the production of penicillinase, which is a major mechanism of resistance to beta lactams.</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 4-amino-1H-imidazole-5-carboxylate is an ionotropic gelator, which means it is able to form gels when mixed with water. It is synthesised from aluminium chloride and primary amines. Ethyl 4-amino-1H-imidazole-5-carboxylate has been shown to have a carbonyl group and triethyl orthoformate as functional groups. The chemical structure of ethyl 4-amino-1H-imidazole-5-carboxylate is heterocyclic with three rings in the molecule. Ethyl 4 amino 1H imidazole 5 carboxylate has been used as a model substrate for biosynthesis studies of α,α'-diaminopropionic acid and its derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>N-(1-Phenylethyl)hydrazinecarbothioamide (HZPCA) is a corrosion inhibitor that is used in acid solutions such as hydrochloric acid, nitric acid, phosphoric acid, and sulfuric acid. It is an organic compound that has been shown to be active against certain metal ions at the adsorption sites. The efficiency of HZPCA adsorption for different metal ions depends on the pH of the solution. HZPCA also has potent inhibitory effects on the corrosion process by reacting with the metal oxide film on metal surfaces and forming an insoluble hydrazine complex. This complex reduces further corrosion by blocking oxygen diffusion to the metal surface.</p>

<p>N-(1H-1,3-Benzodiazol-2-yl)acetamide is a hydrophilic molecule that has been shown to be active against helminths. It is used as an experimental drug for the treatment of schistosomiasis. N-(1H-1,3-Benzodiazol-2-yl)acetamide binds to the nuclear membrane and prevents the formation of hydrogen bonds with cytosine residues. This leads to a disruption in the helical structure of DNA and causes cell death. The compound also inhibits protein synthesis by binding to ribosomes and inhibiting peptide bond formation. In addition, N-(1H-1,3-Benzodiazol-2-yl)acetamide has been shown to have antimicrobial activity against bacteria and fungi.<br>The profile of this molecule can be altered by changing its substituents on benzene ring or cyclopropane ring. It can also be modified by altering the</p>

<p>1-Ethyl-2-methyl-1H-imidazole is an imidazole derivative that has been shown to be active against a variety of bacteria. It can be used as an antimicrobial agent in medicines, such as antibiotics and antifungal agents. 1-Ethyl-2-methyl-1H-imidazole is also used as a chemical intermediate for the synthesis of other compounds. This compound has been shown to have bifunctional properties by inhibiting both ion channels and membranes, which may be related to its antibacterial activity. The compound is stable at high temperatures and displays good chemical stability in aqueous media. It has also been shown to have antihypertensive effects in animal models.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>