Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

4-n-Propylpiperidine is a piperidine derivative, which is used as a building block in organic synthesis. It has been shown to have anticancer properties in some models of cancer and can be used to treat testicular cancer. 4-n-Propylpiperidine is a carcinogen that can cause mutations and DNA damage, leading to uncontrolled cellular growth. 4-n-Propylpiperidine is an amide or piperazine derivative that has been found to be systematically active against certain types of tumors. This compound is also toxic to the testes and other tissues, and can cause kidney damage.

Versatile small molecule scaffold

3,3-Dimethylglutarimide is a molecule that has been shown to inhibit the enzyme butyrylcholinesterase in a stepwise manner. This inhibition prevents the breakdown of acetylcholine, which leads to increased levels of this neurotransmitter and an improvement in cognition. 3,3-Dimethylglutarimide also has protonation properties that allow it to form complexes with metal ions such as zinc and copper. These complexes are formed by the interaction of functional groups on the molecules with protons on the metal ions.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Methylcyclohexane-1-carboxamide is a sclerotiorin, which are natural substances that have been shown to have inhibitory effects against fungi. It has been shown to be effective against Sclerotinia sclerotiorum and Gaseous Botrytis cinerea. The inhibition of sclerotiorin 1-methylcyclohexane-1-carboxamide is due to its ability to inhibit the synthesis of ergosterol, which is an important component of the fungal cell membrane. This drug has also been shown to have inhibitory effects on carbon bond formation in natural substances such as ginseng root or solid form.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(Propan-2-yl)butanedioic acid is a depsipeptide with microbial activity. It inhibits bacterial growth by binding to the beta-subunit of ATP synthase in the microbial cell membrane, which prevents the synthesis of ATP and other metabolites required for cell division. 2-(Propan-2-yl)butanedioic acid has been shown to inhibit Salmonella typhimurium and Staphylococcus aureus in vitro and in vivo. The mechanism by which this drug inhibits bacterial growth is not yet fully understood, but it may be due to its ability to bind to fatty acids or hydrocarbons that are found on the surface of microorganisms.

3,5-Dimethyl-2-cyclohexen-1-one is a β-unsaturated ketone that has been synthesized using an efficient method. It has been shown to have anti-inflammatory properties and is used for the treatment of pulmonary fibrosis in humans. The compound also binds to polyene compounds and supramolecular substrates. 3,5-Dimethyl-2-cyclohexen-1-one reacts with chloride ions to form a β unsaturated ketone chloride that can undergo alkylation with an electron donor such as acetonitrile. This reaction is catalyzed by microsomal cytochrome P450 enzymes and requires a reaction time of about two hours to complete.

Versatile small molecule scaffold