Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4H,5H,6H-Thieno[3,4-c]pyrrole-4,6-dione is a potent antitumor agent that inhibits the activity of protein kinases. It has been shown to have the ability to inhibit tumor growth in animal models and has been shown to be effective against resistant microorganisms such as Staphylococcus aureus and Mycobacterium tuberculosis. 4H,5H,6H-Thieno[3,4-c]pyrrole-4,6-dione has also been shown to improve hematopoiesis by stimulating colony stimulating factor production. This compound is metabolized through a number of metabolic transformations including oxidative deamination by monoamine oxidase or pyridoxal phosphate dependent aminotransferases. The biological properties of 4H,5H,6H-Thieno[3,4-c]pyrrole-4

Versatile small molecule scaffold

3-(Thiophen-2-yl)propan-1-amine is an organic solvent that is used as a reactant in the production of polyphosphoric acid. It is also used in the synthesis of pharmaceuticals. This compound can be produced by reacting chloroformate with propylamine and aluminium chloride in a solution of hydrochloric acid, producing 3-(thiophen-2-yl)propan-1-amine and hydrogen chloride gas. The reaction can also be carried out using phosphoryl chloride and propylamine to produce 3-(thiophen-2-yl)propan-1-amine and phosphorus pentoxide.

Mesityl oxide is a colorless liquid with a sweet odor that is used as a flavor and fragrance agent. It can be found in the volatile fraction of many essential oils such as lavender, rosemary, and sage. Mesityl oxide has been identified by gas chromatography-mass spectrometry (GC-MS) to be present in the volatile fraction of these oils. It is also found in many foods such as red wine, coffee, and beer. Mesityl oxide has been shown to have differentiating properties in initially similar samples. This compound can be detected by GC-MS using an oxidized pentane extraction procedure.
Mesityl oxide is not considered to be toxic at low doses but may cause irritation at high doses.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Quinoline-4-sulfonic acid is a chemical compound that belongs to the class of quinoline derivatives. It has a linear range of activity and inhibits enzymes such as glutamicum, organisms, additives, metal ion, alkali metal, heterocycle, methyl groups and oxygenated. The optimum pH for this compound is 7. Quinoline-4-sulfonic acid is not very soluble in water but is soluble in an organic solvent such as acetone or ethanol. This molecule has been shown to be active against strains of Escherichia coli.