Building Blocks

Versatile small molecule scaffold

2-Amino-4-bromobenzamide is a ring-opening reaction system that is used in the synthesis of isatins. It has been shown to be an efficient and rapid method for the synthesis of this class of heterocyclic compounds. The oxidative nature of this reaction makes it useful for generating reactive intermediates, which can be used for further transformations.

Versatile small molecule scaffold

Versatile small molecule scaffold

1,2-Thiazinane-1,1-dione is a short-chain alkylating agent that has been shown to have neuropathic and inflammatory pain relief. It binds to a number of halides and inhibits their action, including the inhibition of angiotensin I-converting enzyme (ACE), which is an antihypertensive agent. 1,2-Thiazinane-1,1-dione also inhibits the production of epoxides in c1-4 alkyl groups. This drug also has antibacterial properties and can be used as a chemical probe for ligand binding studies.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-(2-Hydroxy-2-methylpropyl)acetamide (HMPA) is a molecule inhibitor that inhibits the activity of inflammatory bowel disease (IBD)-associated kinases. HMPA is a member of a family of molecules that are inhibitors of IBD-associated kinases, which may be useful for the treatment of IBD. HMPA has shown in vitro inhibition against two kinases, JNK1 and p38 MAPK, which are both important mediators in the progression of IBD. This drug may be used to inhibit inflammation in the digestive tract by blocking these inflammatory pathways.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Methylphthalic Acid is a chemical that is used in the production of polyvinyl chloride. It is produced by the dioxygenation of phthalic anhydride and methanol, which produces 3-methylphthalic acid as well as 1,1-dichloroethane. The chemical can be used as a surfactant in polyvinyl chloride and styrene production processes. 3-Methylphthalic Acid has been shown to have adverse health effects on laboratory animals, including polyvinyl chloride workers who are exposed to it for prolonged periods of time. The chemical can cause irritation and corrosion to skin and eyes, as well as damage to the liver and kidneys.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

((Cyclopent-3-en-1-yloxy)methyl)benzene (CPMB) is a cyclopentanoid that is found in nature. It has a hydrophilic substituent on the 3rd carbon and a hydroxyl group on the 1st carbon. The substitution at the 3rd carbon is an unresolved stereoisomer. CPMB is also a natural product that can be found in mixtures with other compounds. It can be synthesized using cyclopentadiene and connect to form a ring, or it can be created by reacting oxygen atoms from hydrogen peroxide with benzene. CPMB has been studied for its biological effects such as inducing sleep, or its potential use in cancer treatments.

Versatile small molecule scaffold

Versatile small molecule scaffold