Building Blocks

Versatile small molecule scaffold

N-Benzyl-N-methylacetamide is a cardiac stimulant and thermogenic that has been shown to increase the rate of metabolism in mammals. It is an electrophile that can be converted to a reactive form by perchlorates and other oxidizing agents. The resulting n-oxide reacts with amino acids, yielding iminium ions that react with amide bonds in proteins, altering their structure and function. N-Benzyl-N-methylacetamide has also been shown to have antioxidant properties in vivo studies on mice. It may also have carcinogenic effects due to its ability to induce oxidative stress and DNA damage.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Hydroxyethyl 2-hydroxypropanoate is a polyester that is produced by the dehydration of ethylene glycol and 2-hydroxyethanol. It is a biodegradable, degradable, and regenerative material that can be used in biomedical applications such as scaffolds for tissue engineering. The hydroxy group on the molecule has been shown to prevent protein adhesion and degradation. This product has been shown to inhibit growth of bacteria such as Staphylococcus aureus and Escherichia coli, which may be due to its ability to block the activity of cellular enzymes.

2-(Benzoylamino)-2-phenylacetic acid is a hydrazone that has been used as a precursor for the synthesis of azoalkenes. It is also biologically active and may be useful for the treatment of cancer.

2-(4-Chlorophenyl)butanoic acid is a metabolite of the drug baclofen. It is produced by Streptomyces, and has been found in cultures, experiments, and soil samples. This compound has been shown to metabolize through microbial metabolism with a chiral center (2R), which can be used as an indicator of microbial activity. 2-(4-Chlorophenyl)butanoic acid also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Isopropylphenylacetic acid is a molecule that belongs to the group of phenylpropionic acids. It has a constant inhibitory effect on the aggregation of an enzyme called chymotrypsin and can be used as an anti-inflammatory compound. 4-Isopropylphenylacetic acid interacts with metal ions such as copper, iron, and zinc, which are necessary for the activation of chymotrypsin. The interaction also inhibits the activity of this enzyme by binding to its active site.

Versatile small molecule scaffold

3-Cycloheptylpropanoic acid is a derivative of cycloaliphatic, piperidine, and carboxylic acids. It is a white crystalline solid with a melting point of 87°C. 3-Cycloheptylpropanoic acid is an intermediate in the synthesis of other compounds, including gastrin and cholecystokinin, which are involved in the regulation of digestive system activity. The receptor ligands for these two hormones are also intermediates in their synthesis. 3-Cycloheptylpropanoic acid has been shown to inhibit gastric acid secretion and increase the production of pancreatic enzymes.

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Phenoxybenzenesulfonamides are reactive compounds that have a wide range of applications. They can be used as intermediates in the synthesis of various chemicals, including perchloroethylene and polymeric conjugates. These sulfonamides have shown potential in the field of medicine, as they exhibit inhibitory effects on epidermal growth factor and growth factor receptors. Additionally, they have been studied for their antioxidant properties, which may help reduce lipid peroxidation and oxidative stress. Research is also being conducted to explore their potential use in drug delivery systems, particularly in combination with anticancer drugs like sorafenib and irinotecan. The acidic nature of these compounds makes them suitable for certain chemical reactions, such as proton transfer processes or electrode reactions. Overall, 4-Phenoxybenzenesulfonamides are versatile compounds with promising applications in various fields.

Versatile small molecule scaffold