Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Ethylpyridin-4-amine is a pyridine that can be synthesized from the amination of 4-nitrophenol. It can also be synthesized by acylation of 2-ethylpyridine with ethyl chloroformate followed by cyclization. This compound has shown to have high yields in reactions involving pyridines and it is often used as a precursor for other compounds.

Versatile small molecule scaffold

5-Phenyl-1H-pyrazin-2-one is a potent inhibitor of tyrosine kinase, which is an enzyme that regulates the activity of cells by transferring phosphate groups from ATP to tyrosine residues. This drug binds to the ATP binding site, resulting in inhibition of the enzyme's activity and reduced cell proliferation. 5-Phenyl-1H-pyrazin-2-one has been shown to be effective in treating rheumatoid arthritis and other autoimmune diseases, with no adverse effects on bone metabolism or blood pressure. It also has no effect on platelet aggregation or erythrocytes.

3,5-Dichlorophthalic acid is a divalent organic acid that is used as an intermediate in the production of other chemicals. 3,5-Dichlorophthalic acid is used as a regulator of plant growth and development. It can also be used to make different n-substituted compounds, such as naphthalene, phthalic anhydride, and 2,6-dichloro-pyridine.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Bromo-1-methylcyclohexane is a monomolecular gas that is used as an intermediate in organic synthesis. It reacts with halides to form cyclopentyl derivatives. This reaction has been shown to be faster than the corresponding reaction of 1-bromocyclohexane with chlorides or bromides. The rate of this reaction may be due to the polarizability and conformational changes of the molecule upon substitution by a methyl group. 1-Bromo-1-methylcyclohexane is also an ionizing reagent, which means it can cause electrophilic reactions to occur on other molecules. It has been found that the solvent effect on this product can affect its reactivity, with solvents such as water having more of an effect than solvents such as benzene. 1-Bromo-1-methylcyclohexane has been shown to interact with other compounds in both transfer and complex

Versatile small molecule scaffold

4-Amino-N-(4-methoxyphenyl)benzamide is a catalytic sulfamate that has been optimized for use in the synthesis of benzimidazole derivatives. 4-Amino-N-(4-methoxyphenyl)benzamide is used as a reagent for the preparation of aldehydes from sulfamic acid and various types of carboxylic acids. The reaction mechanism involves nucleophilic attack by the hydroxyl group from the sulfamate on the carbonyl carbon atom to form an intermediate, which then reacts with water to release hydrogen sulfate and form a new double bond.

Versatile small molecule scaffold

Versatile small molecule scaffold

(3,3,3-Trifluoroprop-1-yn-1-yl)benzene is a reaction product that can be used to inhibit the activity of metalloprotease and as an anti-cancer agent. This compound inhibits the enzyme that causes chronic kidney disease and degenerative diseases. It is a potent inhibitor of metalloprotease, which is involved in cancer progression, fatty acid synthesis and bone formation. The effective dose for this drug is between 1 and 10mg/kg body weight. It has been shown to have an asymmetric synthesis with the use of amido groups. (3,3,3-Trifluoroprop-1-yn-1-yl)benzene also has antirheumatic properties due to its ability to inhibit proteases such as matrix metalloproteinases and cathepsins.

Versatile small molecule scaffold

Amyl acetate is a reactive, volatile organic compound that is used in the manufacture of plasticizers, resins, and synthetic rubber. It is also used as a solvent for dyes and pigments, as well as a flavoring agent in food processing. Amyl acetate has been shown to have antimicrobial properties against human pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, and Salmonella enterica. The antimicrobial activity of this molecule may be due to its ability to react with cellular components such as proteins and lipids. Amyl acetate also inhibits the growth of microorganisms by inhibiting their synthesis of essential biomolecules like amino acids and nucleic acids.

5-Ethenyl-2-methoxyphenol is a volatile compound that has been isolated from the bark of the cinnamon tree. It has shown anticancer activities "in vitro" and "in vivo". 5-Ethenyl-2-methoxyphenol has been shown to be demethylated by cytochrome P450 enzymes, which may result in its antitumor activity. This active compound can also be detected in postharvested fruit and vegetables as well as processed foods such as apple juice, tomato sauce, and dried fruits. 5-Ethenyl-2-methoxyphenol is responsible for the characteristic flavor of cinnamon, so it is often used as a flavoring agent in food processing.

Acetic acid, dibromo-, ethyl ester is a reactive molecule that can be used as a nucleophilic substituent. It has hydroxyl group and ruthenium complex. It is a particle that can be used in the production of monoclonal antibodies. Acetic acid, dibromo-, ethyl ester also has viscosity and polycarboxylic acid. This chemical reacts with β-unsaturated ketones to form polymerization initiator. Acetic acid, dibromo-, ethyl ester also has carbonyl group and monoclonal antibodies. Acetic acid, dibromo-, ethyl ester can be conjugated with ethyl bromoacetate to produce conjugates.

2-[(3-Nitrophenyl)formamido]acetic acid (2NPA) is a modifying agent that has been used in the modification of carboxyl groups. It can react with nucleophiles to form adducts and with carbodiimides to form ureas. 2NPA reacts with amino acids, peptides, and other nitrogenous compounds at their carboxyl groups to form ester or amide bonds. The nature of the residues after modification varies depending on the nature of the carboxyl group that was modified.