Building Blocks

2-Ethenyl-1H-indole is an organic compound that can be synthesized from a Friedel-Crafts reaction of a fatty acid and an alkyl halide. The cycloaddition process of 2-ethenyl-1H-indole to form the bicyclic system was found to proceed through a [4+2] cycloaddition mechanism with the formation of a strained six membered ring between the two carbon atoms at the junction. This product is then converted into biofuels, such as particle or fatty acids, by analytical chemistry. Preparative high performance liquid chromatography (HPLC) has been used to separate glycogen synthase kinase 3 (GSK3) oligosaccharides, which have been shown to be involved in various biological processes.

4'-(Methylsulfonyl)acetanilide is an organic compound that has been shown to have antibacterial and antiviral activity. It targets the benzene nucleus, and inhibits the synthesis of nucleic acids by inhibiting the enzyme ribonucleotide reductase. 4'-(Methylsulfonyl)acetanilide also inhibits viral replication, by binding to the active site of a viral protein (a DNA polymerase), which blocks the incorporation of nucleotides into the virus's DNA. In addition, 4'-(methylsulfonyl)acetanilide is an anti-helminthic agent, as it can inhibit worm motility and kill larvae in vitro. The structure-activity relationships between this molecule and other benzimidazole derivatives were analysed in order to identify new potential drugs for treating diseases caused by viruses or parasites.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Chloro-5-nitroquinoline is an oxidized aminoquinoline that is synthesized from nitric acid and benzene. It contains a nitro group, which makes it susceptible to oxidation. 2-Chloro-5-nitroquinoline is used as a solvent for rubber, plastics, and waxes. It can also be used as a solvent in the production of quinolines and other nitrogen compounds. Nitration of this compound produces 2-chloroquinoline, which can be transformed into 2-chloroquinolinium hydroxide by reaction with sodium hydroxide. The substituent on the ortho position can be determined by oleum or bromine water.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3,4-Dihydro-1H-2-benzothiopyran-4-ol is a heterocyclic compound that has been the subject of X-ray diffraction studies. The structure consists of a benzene ring with two oxygen atoms at positions 1 and 2 and a sulfur atom at position 4. It is also known as 3,4-dihydrobenzothiopyran or thioxanthone. The compound is used to make polysulfides, sulfoxides, and sulfones. 3,4-Dihydro-1H-2-benzothiopyran-4-ol is also used as a precursor for other compounds such as thioxanthone (a photosensitizer), sulfoxide (a drug), and sulfate (a reagent).