Building Blocks

<p>Applications An intermediate in the preparation of a potential inhibitor of GAR Tfase.<br>References Cheng, H. et al.: Bioorg. Med. Chem., 13, 3593 (2005)<br></p>

<p>Applications N-Boc-p-phenylenediamine is the boc protected compound of 1,4-Phenylenediamine (P319845). 1,4-Phenylenediamine is a hair dye component, paraphenylenediamine, as a contact allergen for treatment of inflammatory diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, K., et al.: J. Med., 13, 131 (1982), Baud, F., et al.: J. Toxicol. Med., 4, 279 (1984), Ashraf, W., et al.: Human Exp. Toxicol., 13, 167 (1994),<br></p>

<p>Applications Dimethyl cyclopropane-1,1-dicarboxylate (cas# 6914-71-2) is a useful research chemical.<br></p>

<p>Applications Propyl Acetoacetate is used as a reagent in the synthesis of 3,4-dihydropyrimidin-2(1H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists.<br>References Crespo, A., et al.: ACS Med. Chem. Lett., 4, 1031 (2013)<br></p>

<p>Applications Formamidine is an intermediate used to prepare Formiminoglycine which is used in biological studies for the metabolism by purinolytic clostridia. It was also used in the synthesis of 5-methyl-4,6-dihydroxypyrimidine.<br>References Duerre, P., et al.: J. Bacteriology, 154, 192 (1983); Novais, H., et al.: J. Phys. Chem., 91, 426 (1987)<br></p>

<p>Applications 2-sec-Butylphenol is a substance used in checking the effect of different enhancers on transdermal permation of insulin. It also acts as one of the substances used as models, which are helpful for aiding screening and development of androgenic compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yerramsetty, K. M., et al.: Int. J. Pharm., 398, 83 (2010); Jia, Y., et al.: isuanji Yu Yingyong Huaxue, 24, 1469 (2007)<br></p>

<p>Applications 2-Fluorobenzaldehyde is a compound that has inhibitory effects on the activity of mushroom tyrosinase, a copper-containing enzyme that is widely used in a number of applications such as direct protein-protein cross linking, and activating tyrosine residues in polypeptides for protein cross-linking to chitosan films.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Halaouli, S., et al.: J. Appl. Microbiol., 100, 219 (2006); Huang, X., et al.: J. Enzyme Inhib. Med. Chem., 21, 413 (2006); Sung-Yum, S., et al.: J. Agric. Food Chem., 51, 2837 (2003);<br></p>

<p>Applications 3-(Methylthio)propylamine (cas# 4104-45-4) is a useful research chemical.<br></p>

<p>Applications cis-2-Hexen-1-ol is used in the invention of a repellent for Oryzaephilus surinamensis.<br>References Xu, W., et al.: Faming Zhuanli Shenqing (2017), CN 107258786 A 20171020<br></p>

<p>Applications α-Chlorophenylacetyl Chloride is a reagent used for dehydrohalogenation of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brady, W.T., et al.: J. Org. Chem., 45, 3525 (1980); Brady, W.T., et al.: J. Org. Chem., 45, 2025 (1980);<br></p>

<p>Applications 1-Adamantyl Isocyanate is used to prepare reaction of nickel(III) diketiminato imido complex with CO.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kogut, E., et al.: J. Am. Chem. Soc., 127, 11248 (2005);<br></p>

<p>Applications Phenylmalonic Acid Mono-5-indanyl Ester is an intermediate in the synthesis of Indanylcarbinicillin (S635000), an compound shown to reduce blood pressure in mammals and also has been used as a β-lactam antibiotic.<br></p>

<p>Stability Moisture and Acid Sensitive<br>Applications (1-Methoxy-2-methylprop-1-enoxy)trimethylsilane is useful in the synthesis of organic compounds such as 1,​1'-​Bis[1-​(1-​methoxycarbonyl-​1-​methyl-​ethyl)​-​3-​butenyl] Ferrocene Monome, Alkylbismuths and N-​Tosyl-α,​β-​dehydroamino Esters.<br>References Espinosa, M., et al.: RC Adv., 6, 15655 (2016); Nishimoto, T., et al.: Chem. Eur. J., 19, 14411 (2013); Wang, J., et al.: Faming Zhuanli Shenqing, CN 103665053 A 20140326 (2014)<br></p>

<p>Applications 2-Bromopropionic Acid is a versatile reactant used in emulsion polymerization in the preparation of reversible addition-fragmentation chain transfer (RAFT) agent.<br>References Ferguson, C., et al.: Macromolecules, 35, 9243 (2002); Ferguson, C., et al.: Macromolecules, 38, 2191 (2005);<br></p>

<p>Applications 4-Nitrophenyl Phosphorodichloridate is used as a reagent in the synthesis of dihydrobenzodioxaphosphocine oxide derivatives which have antioxidant activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Siva Prasad, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2016, ahead of print)<br></p>

<p>Applications A precursor to 3-Methyl-2-butenyl-1-thiol which is very unstable. We will provide a detailed procedure for the preparation of the thiol from the thiolacetate with spectral data upon request.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Ethyl 3-benzoylacrylate is an impurity of Enalapril (E555250), an antihypertensive and an angiotensin-converting enzyme (ACE) inhibitor.<br>References Gross, M., et al.: J. Pharmacol. Exp. Ther., 216, 552 (1980), Gomez, H.J., et al.: J. Cardiovasc. Pharmacol., 15, Suppl. 3, S26-S29, (1990), MacFadyen, J., et al.: Clin. Pharmacokinet., 25, 274 (1993), Malini, P.L.: Adv. Ther., 10, 253 (1993),<br></p>

<p>Applications Phenyl 2-Chloroethyl Ether (cas# 622-86-6) is a compound useful in organic synthesis.<br></p>