Building Blocks

<p>Applications 2,3-Diaminophenol<br></p>

<p>Applications 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2 is a labelled 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine (D416350), used in the preparation of pterin-based inhibitors.<br>References Hevener, K. et al.: J. Med. Chem., 53, 166 (2010)<br></p>

<p>Applications DI-Tert-Butyl Hydrazodicarboxylate (cas# 16466-61-8) is a useful research chemical.<br></p>

<p>Applications 2-[4-(1,1-Dicarboethoxy)benzyl]-2-methyl Malonic Acid-d3 (cas# 1346604-53-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Norflurazon (N684500) intermediate.<br>References Mazzola, E.P., et al.: J. Agric. Food Chem., 32, 1102 (1984),<br></p>

<p>Applications Diethyl Benzylmalonate (cas# 607-81-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Diethyl Butylethylmalonate-d5 is the isotope labelled analog of Diethyl Butylethylmalonate, a derivative of Diethyl 2-n-Butylmalonate (D443880) which is a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria.<br>References Yang, S., et al.: Eur. J. Med. Chem., 86, 133 (2014); Shi, W., et al.: Bioorg. Med. Chem. Lett., 20, 3592 (2010)<br></p>

<p>Applications Diethyl 2-n-Butylmalonate is used as a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria.<br>References Yang, S., et al.: Eur. J. Med. Chem., 86, 133 (2014); Shi, W., et al.: Bioorg. Med. Chem. Lett., 20, 3592 (2010)<br></p>

<p>Applications N,N-Diethyl(trimethylsilyl)amine is a chemical reagent with wide application in organic chemistry. Used in stereospecific addition reactions as well as in SN2 nucleophilic substitutions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bassindale, A. et al.: J. Organometal. Chem., 667, 66 (2003); Hagiwara, H. et al.: J. Chem. Soc., Perk Trans., 3, 316 (2002);<br></p>

<p>Applications 2,2,5,5-Tetramethyl-3-amino-pyrrolidine-1-oxyl Free Radical is a highly reactive spin-label compound.<br></p>

<p>Applications Diphenyl Chlorophosphonate, is a building block used for the synthesis of various chemical compounds. It can be used for the synthesis of phosphate esters of polyhedral hydroxyboranes, showing enhanced tumor uptake.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bechtold, R., et al.: J. Med. Chem., 18, 371 (1975);<br></p>

<p>Applications Methyl β-Resorcylate, is a building block used for the synthesis of different pharmaceutical compounds. It can be used for the synthesis of series of CCR1 antagonists based upon spirocyclic compounds.<br>References Hossain, N., et al.: Bioorg. Med. Chem. Lett., 23, 3500 (2013);<br></p>

<p>Applications (1-Ethoxycyclopropoxy)trimethylsilane used as a reactant in the synthesis of di-, tri- and tetracyclopropylhydrazines. Also used as reagent in the synthesis of g elsemoxonine which is found in gelsemium plant species that is used in traditional asian medicine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shestakov, A., et al.: Chem. Commun., 52, 2398 (2016); Diethelm, S., et al.: J. Am. Chem. Soc., 137, 6084 (2015);<br></p>

<p>Applications Ethyl 2-Aminothiophene-3-carboxylate (cas# 31891-06-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Piperonylpiperazine (cas# 32231-06-4) is a compound useful in organic synthesis.<br>References Min, J. Z. et at., Biom. Chrom. 24, 1287 (2010); Mitrea, N. et al., Bioanalysis 2, 1211 (2010)<br></p>

<p>Applications 2-Fluorocinnamic acid, 98% (cas# 451-69-4) is a useful research chemical.<br></p>

<p>Applications Pinacol is used in the synthesis of organic reagents such as alkenylphenylphosphonates and alkenylboronates.<br>References Peng, A. et al.: J. Fluor. Chem., 151, 58 (2013); Mazzacano, T. et al.: J. Am. Chem. Soc., 135, 17258 (2013);<br></p>

<p>Applications 4-​Hydroxy-​7-​methoxy-6-​quinolinecarboxamide​ is useful in the synthetic preparation of Lenvatinib (L329400(P)) with high purity. Lenvatinib is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.<br>References Liu, S., et al.: Faming Zhuanli Shenqing (2020), CN 111377865 A; Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)<br></p>