Building Blocks

<p>Applications 2,3-Diaminophenol<br></p>

<p>Applications Diethyl Butylethylmalonate-d5 is the isotope labelled analog of Diethyl Butylethylmalonate, a derivative of Diethyl 2-n-Butylmalonate (D443880) which is a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria.<br>References Yang, S., et al.: Eur. J. Med. Chem., 86, 133 (2014); Shi, W., et al.: Bioorg. Med. Chem. Lett., 20, 3592 (2010)<br></p>

<p>Applications Acetamidine Hydrochloride (cas# 124-42-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Dodecyne (CAS# 765-03-7) is a useful research chemical compound.<br></p>

<p>Applications Diaminomaleonitrile is a reagent used for the synthesis of 1,4-diazepine-2,3-dicarbonitrile dervatives. Also, it is used for the synthesis of Diaminomaleonitrile-based Schiff bases with a donor-acceptor structure and an aggregation-enhanced emission feature.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wieczorek, E., et al.: Tetrahedron Lett., 58, 758-761 (2017); Han, T., et al.: J. Mater. Chem. C Mater. Opt. Electron Devices, 4, 10430-10434 (2016);<br></p>

<p>Applications Bis(2,2,2-Trichloroethyl) Phosphorochloridate acts as a reagent for the preparation, anticancer, and structure-activity relationship of norcantharidin analogs. Preparation and antiviral activity of amino-nucleosides and nucleotides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tarleton, M., et al.: Eur. J. Med. Chem., 54, 573 (2012); McGuigan, C., et al.: Bioorg. Med. Chem. Lett., 6, 2445 (1996)<br></p>

<p>Applications Intermediate in the preparation of Ertapenem (E635000).<br></p>

<p>Applications This compound has been shown to inhibit iodothyronine 5’-deiodinase, the enzyme responsible for the 5’-deiodination of thyroxine in human liver cells.<br>References Harbottle, R., et al.: Biochem. J., 217, 485 (1984),<br></p>

<p>Applications Ethyl 4-Iodobenzoate (cas# 51934-41-9) is a compound useful in organic synthesis.<br></p>

<p>Applications trans-(1R,2R)-N,N’-Bismethyl-1,2-cyclohexanediamine is a useful research chemical for organic synthesis and other chemical processes.<br>References Bollenbach, M., et al.: Chem. Eur. J., 23, 13676 (2017); Thaisrivongs, D. A., et al.: Org. Lett., 18, 5780 (2016)<br></p>

<p>Stability Hygroscopic<br>Applications Dimethyl Phosphite is used as a reagent in the synthesis of 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. It is also used as a reagent in the synthesis of estafiatin phosphonate derivatives which exhibit antibacterial and antifungal activity.<br>References Suleimen, E.M., et al.: Chem. Nat. Compd., 50, 846 (2014); Wang, L., et al.: Bioorg. Med. Chem. Lett., 24, 3739 (2014)<br></p>

<p>Applications Used for synthesis of Rho kinase inhibitors.<br>References Biggadike, K., et al.: J. Med. Chem., 50, 6519 (2007), Cheng, Y., et al.: Bioorg. Med. Chem., 16, 4617 (2008),<br></p>

<p>Applications 3,5-Diiodosalicylic Acid is an metabolite of Aspirin (A187780), an anti-inflammatory, anti-platelet and cancer-preventive agent. 3,5-Diiodosalicylic Acid was shown to exhibit agonist activity at GPR35, a orphan G protein coupled receptor.<br>References Deng, H.Y., et al.: Arch. Pharmacol., 385, 729 (2012); Blandin, V., et al.: Molec. Pharmacol., 58, 1461 (2000);<br></p>

<p>Applications Diethyl 2-n-Butylmalonate is used as a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria.<br>References Yang, S., et al.: Eur. J. Med. Chem., 86, 133 (2014); Shi, W., et al.: Bioorg. Med. Chem. Lett., 20, 3592 (2010)<br></p>

<p>Applications 1-(Benzyloxy)propan-2-one (cas# 22539-93-1) is a useful research chemical.<br></p>

<p>Applications Phthalodinitrile monomers can be polymerized thermally in the presence of small amounts of curing agents into thermosetting polymers. Phthalodinitrile is a precursor to phthalocyanine which is used as a dye or pigment.<br>References Sastri, S. B. and Keller, T. M.: J. Polym. Sci. A Polym. Chem., 36, 1885-1890(1998), Löbbert, G. Phthalocyanines. In Ullmann's Encyclopedia of Industrial Chemistry, (Ed.)., (2000).<br></p>

<p>Applications Intermediate in the production of labelled Cicletanine<br></p>

<p>Applications 2,3-Dimethoxybenzoic acid<br></p>