Building Blocks

<p>Applications 2,6-Dibromopyridine is used as a starting material to synthesize 2,2’-bipyridines (such as 5-Cyano-1,6-dihydro-6-oxo-[3,4'-bipyridine]-2-carboxylic Acid [C979150]) via a Stille-type cross-coupling reaction. 2,6-Dibromopyridine is also used as a reagent to synthesize pyridylpyrimidine fungicides, compounds that eliminate fungi by cycling copper through the cell membrane, where it reaches toxic levels.<br>References Hargreaves, S., et al.: Tetrahedron Lett., 41, 1653 (2000); Heller, M. &amp; Schubert, U.: J. Org. Chem., 67, 8269 (2002); Simkovsky, N., et al.: J. Chem. Soc. Perk. Trans. 1, 16, 1847 (2002)<br></p>

<p>Applications 1,1-dimethylguanidine Sulfate (cas# 598-65-2) is a useful research chemical.<br></p>

<p>Applications 2-Fluorocinnamic acid, 98% (cas# 451-69-4) is a useful research chemical.<br></p>

<p>Applications A metabolite of Tryptophan-niacin.<br>References Yuyama, S. et al.: Adv. Exp. Med. Biol. 294, 475 (1991).<br></p>

<p>Applications Formamidine is an intermediate used to prepare Formiminoglycine which is used in biological studies for the metabolism by purinolytic clostridia. It was also used in the synthesis of 5-methyl-4,6-dihydroxypyrimidine.<br>References Duerre, P., et al.: J. Bacteriology, 154, 192 (1983); Novais, H., et al.: J. Phys. Chem., 91, 426 (1987)<br></p>

<p>Applications N,N-DIMETHYLFORMAMIDE DINEOPENTYL ACETAL (cas# 4909-78-8) is a useful research chemical.<br></p>

<p>Applications Methyl 2-bromobenzoate<br></p>

<p>Applications rac-Trifluorolactic Acid is a derivative of DL-Lactic Acid (L113490) which occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity.<br>References He, W. et al.: Comp. Biochem. Phys. Part A: Mol. Int. Phys., 166, 308 (2013)<br></p>

<p>Applications trans-(1R,2R)-N,N’-Bismethyl-1,2-cyclohexanediamine is a useful research chemical for organic synthesis and other chemical processes.<br>References Bollenbach, M., et al.: Chem. Eur. J., 23, 13676 (2017); Thaisrivongs, D. A., et al.: Org. Lett., 18, 5780 (2016)<br></p>

<p>Applications Bis(2,2,2-Trichloroethyl) Phosphorochloridate acts as a reagent for the preparation, anticancer, and structure-activity relationship of norcantharidin analogs. Preparation and antiviral activity of amino-nucleosides and nucleotides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tarleton, M., et al.: Eur. J. Med. Chem., 54, 573 (2012); McGuigan, C., et al.: Bioorg. Med. Chem. Lett., 6, 2445 (1996)<br></p>

<p>Applications 3-[(tert-Butyldimethylsilyl)oxy]-1-propanol (cas# 73842-99-6) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture sensitive<br>Applications Octanoyl Chloride is commonly used as an acylating agent for a variety of compounds such as sugars (e.g. Sucrose [S697000]), aromatic compounds (e.g. Anisole [A673900]), and monoglycerides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bass, D., et al.: J. Biol. Chem., 263, 19610 (1988); Ganong, B., et al.: P. Natl. Acad. Sci. USA, 83, 1184 (1986); Shih, P., et al.: Catal. Today, 93-95, 365 (2004); Thévenet, S., et al.: J. Carbohyd. Chem., 16, 691 (1997)<br></p>

<p>Applications Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors.<br>References Dufer, M. et al.: Biochem. J. et al.: 15, 368 (2002); Andres, J. et al.: Bioorg. Med. Chem. Lett., 23, 785 (2013);<br></p>

<p>Applications A precursor to 3-Methyl-2-butenyl-1-thiol which is very unstable. We will provide a detailed procedure for the preparation of the thiol from the thiolacetate with spectral data upon request.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Cinnamyl Bromide acts as a reagent in the synthesis of Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keller, M., et al.: Eur. J. Med. Chem., 109, 13 (2016)<br></p>

<p>Applications 2-[4-(1,1-Dicarboethoxy)benzyl]-2-methyl Malonic Acid-d3 (cas# 1346604-53-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4,4-Trifluoro-3-oxobutanoic Acid Ethyl Ester is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References He, J.Y., et al.: Biotechnol. J., 2, 260 (2007); Mize, P.D., et al.: Anal. Biochem., 179, 229 (1989);<br></p>

<p>Applications Isopropyl Acetoacetate (cas# 542-08-5) is a compound useful in organic synthesis.<br></p>