Building Blocks

<p>Applications Used as a reactant or reagent in preparation of N-alkyl carbamates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lazewska, D. et al.: BioMed. Chem. Let., 19, 6682 (2009);<br></p>

<p>Applications 1-Ethynylcyclohexanol is used in the preparation of 9-methyladenines used as adenosine receptor antagonists. Also used in the cycloadition of alkynes to organic azides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harada, H. et al.: J. Med. Chem. 44, 170 (2001); Zhang, L. et al.: J. Am. Chem. Soc., 127, 15998 (2005);<br></p>

<p>Applications 4-Methoxy-3-nitrobenzoic acid is a substituted nitrobenzoic acid reagent for proteomics and organic synthesis research.<br>References Achary, R. et al.: Bioorg. Med. Chem. Lett., 27, 2185 (2017);<br></p>

<p>Stability Volatile<br>Applications Hexamethyldisilane is an organic silylating and disilylating reagent. It is also a useful reagent for reductive coupling, reductive deuteration, aroylarylation, carbosilylation, insertion, deuteration and dimerization reactions.<br>References Xiao, G., et al.: Tetrahedron Lett., 59, 1836 (2018); Lu, A., et al.: Angew. Chem. Int. Ed., 57, 3233 (2018); Deb, M., et al.: New J. Chem., 41, 14528 (2017); Hiyama, T., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2010)<br></p>

<p>Applications (±)-3-Heptanol, is a volatile components of various plants, and can be used as flavor and fragrance ingredients. It is also used as building block used for the synthesis of various chemicals. It is used for the preparation of biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, I., et al.: Bioorg. Med. Chem. Lett., 55 (18), 5889 (2012); Gibka, J., et al.: Zeszyty Naukowe - Politechnika Lodzka, 60, 65 (1998);<br></p>

<p>Applications 4-​Hydroxy-​7-​methoxy-6-​quinolinecarboxamide​ is useful in the synthetic preparation of Lenvatinib (L329400(P)) with high purity. Lenvatinib is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.<br>References Liu, S., et al.: Faming Zhuanli Shenqing (2020), CN 111377865 A; Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)<br></p>

<p>Applications 3-Methyl-2-buten-1-ol can be used as an additive to improve the antiknock properties of gasoline.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mack, J. Hunter, et al.: Fuel, 117(PB), 939-943 (2014)<br></p>

<p>Applications Insecticidal activity.<br>References Durden, J. et al.; J. Agr. Food Chem. 17, 94 (1969)<br></p>

<p>Applications Formamidine is an intermediate used to prepare Formiminoglycine which is used in biological studies for the metabolism by purinolytic clostridia. It was also used in the synthesis of 5-methyl-4,6-dihydroxypyrimidine.<br>References Duerre, P., et al.: J. Bacteriology, 154, 192 (1983); Novais, H., et al.: J. Phys. Chem., 91, 426 (1987)<br></p>

<p>Applications 3-(Methylthio)propylamine (cas# 4104-45-4) is a useful research chemical.<br></p>

<p>Applications An intermediate for the synthesis of many biologically active molecules including receptor ligands and enzyme inhibitors<br>References Miyashita, A., et al.: Chem. Pharm. Bull., 45, 1235 (1997), Collins, I., et al.: J. Med. Chem., 45, 1887 (2002), Miller, W.H., et al.: Bioorg. Med. Chem. Lett., 13, 1483 (2003),<br></p>

<p>Applications 2-Fluorocinnamic acid, 98% (cas# 451-69-4) is a useful research chemical.<br></p>

<p>Applications Myristoyl Chloride is a building block that has been used to form esters on rubber wood. Esterification reduces crystalinity of wood and reduces light0induced color changes (phot-yellowing ) at wood surfaces. Myristoyl Chloride has also been used in the modification of isophalate-PEG copolymers to make amphiphilic copolymers as nanocarriers for drug delivery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salla, J., et. al.: J. Wood Chem. Tech. , 32, 121 (2012); Gupta, B., et. al.: J. Macromol. Sci. Pure, 48, 1009 (2011)<br></p>

<p>Applications 2-HEPTYN-1-OL (cas# 1002-36-4) is a useful research chemical.<br></p>

<p>Applications A precursor to 3-Methyl-2-butenyl-1-thiol which is very unstable. We will provide a detailed procedure for the preparation of the thiol from the thiolacetate with spectral data upon request.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-​Amino-​6-​methylpyridine is a reagent used in the identification of selective inhibitor for phosphatidylinositol 3-kinase (PI3Kα).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, M. S., et al.: Bioorg. Med. Chem., 25, 1481-1486 (2017);<br></p>

<p>Stability Air Sensitive, Stench<br>Applications Allyl Mercaptan (&gt;75%) can be used to treat Alzheimer's, stroke, cardiovascular and other amyloid related diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Postrel, R., U.S. Pat. Appl. Publ. US 20200215009 A1, 10, (2020);<br></p>