Building Blocks

<p>Applications (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) (cas# 19249-03-7) is a useful research chemical.<br></p>

<p>Applications Methyl 4-nitrobenzoate (cas# 619-50-1) is a useful research chemical.<br></p>

<p>Applications N-Boc-p-phenylenediamine is the boc protected compound of 1,4-Phenylenediamine (P319845). 1,4-Phenylenediamine is a hair dye component, paraphenylenediamine, as a contact allergen for treatment of inflammatory diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, K., et al.: J. Med., 13, 131 (1982), Baud, F., et al.: J. Toxicol. Med., 4, 279 (1984), Ashraf, W., et al.: Human Exp. Toxicol., 13, 167 (1994),<br></p>

<p>Applications 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic Acid 1,1-Dimethylethyl Ester (cas# 123387-51-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Phenyl 2-Chloroethyl Ether (cas# 622-86-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Methoxyphenylacetic Acid (cas# 1798-09-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Intermediate in the preparation of Carvedilol derivatives.<br>References Mewshaw, R., et al.: J. Med. Chem., 47, 3823 (2004),<br></p>

<p>Applications (1R,2S)-rel-1,2-Cyclopentanedicarboxylic Acid is a Possible inhibitor of prolidase.<br>References Mock, W. et al.; J. Biol. Chem. 265, 19606 (1990)<br></p>

<p>Applications Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level.<br>References Yin, L., et al.: PLoS One., 7, 48048 (2012); Rodriguez, J.D.,e t al.: Chem. Biochem. Engin. Quart., 20, 173 (2006);<br></p>

<p>Applications Butyric Anhydride is a chemical reagent used in the synthesis of amidoamine dendron-based co-adsorbents used in the improvement of dye-sensitized solar cells. Also used in the synthesis of allopurinol derivatives for their activity against Trypanosoma cruzi.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, J. et al.: J. Mat. Chem. Mat. Energy Sust., 1, 14524 (2013); Raviolo, M. et al.: 69, 455 (2013);<br></p>

<p>Applications Ethyl 2-Oxo-2-(2-oxotetrahydrofuran-3-yl)acetate is an intermediate formed in the synthesis of 5-[[(Dimethylamino)iminomethyl]amino]-2-oxopentanoic Acid (D471015), a metabolite of asymmetric dimethylarginine.<br>References Martens-Lobenhoffer, J. et al.: Anal Biochem., 419, 234 (2011)<br></p>

<p>Applications 3-Mercaptophenol is a versatile reactant used in the study of mechanism and catalysis of the native chemical ligation reaction. It was also used as a reactant in the synthesis and biological evaluation of HSP90 inhibitors based on molecular dynamic calculated conformational analysis of radicicol and its analogs.<br>References Moulin, E., et al.: J. Am. Chem. Soc., 127, 6999 (2005); Johnson, E., Kent, S.: J. Am. Chem. Soc., 128, 6640 (2006);<br></p>

<p>Applications (E)-2-Pentenal, is a flavor volatile found in tomato, virgin olive oil and sardine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Methoxypropionitrile (cas# 110-67-8) is a useful research chemical.<br></p>

<p>Applications trans-Cinnamoyl chloride (cas# 102-92-1) is a useful research chemical.<br></p>

<p>Applications 4-Chloropyridine n-oxide (cas# 1121-76-2) is a useful research chemical.<br></p>

<p>Applications An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.L-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion.The intermediate, 2-mercaptohistine has been used for the<br>References Makinen, K.K., et al.: Eur. J. Biochem., 123, 171 (1982), Howard, R.J., et al.: Biochem. Pharmacol., 35, 1589 (1986),<br></p>

<p>Applications Diethyl Phenylmalonate is a reagent used in the synthesis of antituberculosis agents.<br>References Ng, P. S., et al.: J. Med. Chem., 106, 144-156 (2015)<br></p>