Building Blocks

<p>Applications 3-Iodobenzonitrile<br></p>

<p>Applications 8-Bromooctan-1-ol (cas# 50816-19-8) is a useful research chemical.<br></p>

<p>Applications 4-Bromocinnamic Acid (cas# 1200-07-3) is a compound useful in organic synthesis.<br>References Patel, C., et al.: Bioorg. Med. Chem. Lett., 16, 4752 (2006), Ghorai, P., et al.: J. Med. Chem., 51, 7193 (2008),<br></p>

<p>Applications Glyoxal Sodium Bisulfite (contains oligomers) (cas# 517-21-5) is a useful research chemical.<br></p>

<p>Applications GLUTARONITRILE (cas# 544-13-8) is a useful research chemical.<br></p>

<p>Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boettecher, B. &amp; Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)<br></p>

<p>Applications An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.L-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion.The intermediate, 2-mercaptohistine has been used for the<br>References Makinen, K.K., et al.: Eur. J. Biochem., 123, 171 (1982), Howard, R.J., et al.: Biochem. Pharmacol., 35, 1589 (1986),<br></p>

<p>Stability Moisture, Light Sensitive<br>Applications Used for derivatization, TLC and HPLC separation, and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2.<br>References Clin. Chim. Acta., 214, 195 (1993), Anal. Lett., 26, 429 (1993)<br></p>

<p>Applications (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) (cas# 19249-03-7) is a useful research chemical.<br></p>

<p>Applications 4,5-Dimethyl-3-isoxazolamine is an isoxazole derivative used in the preparation of a varitey of biologically active compounds such as selective ETA receptor antagonists.<br>References Murugesan, N. et al.: J. Med. Chem., 46, 125 (2003);<br></p>

<p>Applications 3-[(tert-Butyldimethylsilyl)oxy]-1-propanol (cas# 73842-99-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Triethyltin Bromide is used as an endocrine disrupting compound, inducing adipogenesis through RXR and PPARγ activation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Grun, F. et al.: Mol. Endocrinol., 20, 2141 (2006); Yano, K. et al.: J. Health Sci., 49, 195 (2003)<br></p>

<p>Applications An intermediate in the preparation of a potential inhibitor of GAR Tfase.<br>References Cheng, H. et al.: Bioorg. Med. Chem., 13, 3593 (2005)<br></p>

<p>Applications Intermediate in the preparation of Ertapenem (E635000).<br></p>

<p>Applications 1,2-Dimethylisothiourea-HI (cas# 41306-45-0) is a useful research chemical.<br></p>

<p>Applications 1-Piperonylpiperazine (cas# 32231-06-4) is a compound useful in organic synthesis.<br>References Min, J. Z. et at., Biom. Chrom. 24, 1287 (2010); Mitrea, N. et al., Bioanalysis 2, 1211 (2010)<br></p>

<p>Applications 3-(Methylthio)propylamine (cas# 4104-45-4) is a useful research chemical.<br></p>